Reproduction in Trypanosomatids: Past and Present
15 páginas, 2 figuras.
Saved in:
| Main Authors: | , , , , , , |
|---|---|
| Other Authors: | |
| Format: | artículo de revisión biblioteca |
| Published: |
Multidisciplinary Digital Publishing Institute
2021
|
| Subjects: | Trypanosomatids, Clonal and sexual reproduction, Genetic exchange, Ploidy, Virulence, Drug resistance, |
| Online Access: | http://hdl.handle.net/10261/245153 http://dx.doi.org/10.13039/501100000780 http://dx.doi.org/10.13039/501100014180 http://dx.doi.org/10.13039/501100003329 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| id |
dig-igm-es-10261-245153 |
|---|---|
| record_format |
koha |
| spelling |
dig-igm-es-10261-2451532022-06-24T09:21:50Z Reproduction in Trypanosomatids: Past and Present Gutiérrez-Corbo, C. Domínguez-Asenjo, Bárbara Martínez Valladares, María Pérez-Pertejo,Y. García-Estrada, Carlos Balaña-Fouce, Rafael Reguera, R. M. Ministerio de Economía y Competitividad (España) Junta de Castilla y León European Commission Martínez Valladares, María [0000-0002-3723-1895] Trypanosomatids Clonal and sexual reproduction Genetic exchange Ploidy Virulence Drug resistance 15 páginas, 2 figuras. Diseases caused by trypanosomatids (Sleeping sickness, Chagas disease, and leishmaniasis) are a serious public health concern in low-income endemic countries. These diseases are produced by single-celled parasites with a diploid genome (although aneuploidy is frequent) organized in pairs of non-condensable chromosomes. To explain the way they reproduce through the analysis of natural populations, the theory of strict clonal propagation of these microorganisms was taken as a rule at the beginning of the studies, since it partially justified their genomic stability. However, numerous experimental works provide evidence of sexual reproduction, thus explaining certain naturally occurring events that link the number of meiosis per mitosis and the frequency of mating. Recent techniques have demonstrated genetic exchange between individuals of the same species under laboratory conditions, as well as the expression of meiosis specific genes. The current debate focuses on the frequency of genomic recombination events and its impact on the natural parasite population structure. This paper reviews the results and techniques used to demonstrate the existence of sex in trypanosomatids, the inheritance of kinetoplast DNA (maxi- and minicircles), the impact of genetic exchange in these parasites, and how it can contribute to the phenotypic diversity of natural populations. This research was partially funded by MINECO; SAF2017-83575-R. The first author CGC (LE255-16) as well as BDA (LE208-17) are recipients of Junta de Castilla y Leon (JCyL) and European Social Found (ESF)’s Fellowships Scheme for Doctoral Training Programs. MMV is funded by the Spanish “Ramon y Cajal” Programme (RYC-2015-18368). 2021-07-02T10:00:12Z 2021-07-02T10:00:12Z 2021 2021-07-02T10:00:13Z artículo de revisión http://purl.org/coar/resource_type/c_dcae04bc doi: 10.3390/biology10060471 issn: 2079-7737 Biology, 10: 471 (2021) http://hdl.handle.net/10261/245153 10.3390/biology10060471 http://dx.doi.org/10.13039/501100000780 http://dx.doi.org/10.13039/501100014180 http://dx.doi.org/10.13039/501100003329 #PLACEHOLDER_PARENT_METADATA_VALUE# #PLACEHOLDER_PARENT_METADATA_VALUE# info:eu-repo/grantAgreement/AEI/Plan Estatal de Investigación Científica y Técnica y de Innovación 2017-2020/SAF2017-83575-R info:eu-repo/grantAgreement/MINECO/Plan Estatal de Investigación Científica y Técnica y de Innovación 2013-2016/RYC-2015-18368 http://dx.doi.org/10.3390/biology10060471 Sí open Multidisciplinary Digital Publishing Institute |
| institution |
IGM ES |
| collection |
DSpace |
| country |
España |
| countrycode |
ES |
| component |
Bibliográfico |
| access |
En linea |
| databasecode |
dig-igm-es |
| tag |
biblioteca |
| region |
Europa del Sur |
| libraryname |
Biblioteca del IGM España |
| topic |
Trypanosomatids Clonal and sexual reproduction Genetic exchange Ploidy Virulence Drug resistance Trypanosomatids Clonal and sexual reproduction Genetic exchange Ploidy Virulence Drug resistance |
| spellingShingle |
Trypanosomatids Clonal and sexual reproduction Genetic exchange Ploidy Virulence Drug resistance Trypanosomatids Clonal and sexual reproduction Genetic exchange Ploidy Virulence Drug resistance Gutiérrez-Corbo, C. Domínguez-Asenjo, Bárbara Martínez Valladares, María Pérez-Pertejo,Y. García-Estrada, Carlos Balaña-Fouce, Rafael Reguera, R. M. Reproduction in Trypanosomatids: Past and Present |
| description |
15 páginas, 2 figuras. |
| author2 |
Ministerio de Economía y Competitividad (España) |
| author_facet |
Ministerio de Economía y Competitividad (España) Gutiérrez-Corbo, C. Domínguez-Asenjo, Bárbara Martínez Valladares, María Pérez-Pertejo,Y. García-Estrada, Carlos Balaña-Fouce, Rafael Reguera, R. M. |
| format |
artículo de revisión |
| topic_facet |
Trypanosomatids Clonal and sexual reproduction Genetic exchange Ploidy Virulence Drug resistance |
| author |
Gutiérrez-Corbo, C. Domínguez-Asenjo, Bárbara Martínez Valladares, María Pérez-Pertejo,Y. García-Estrada, Carlos Balaña-Fouce, Rafael Reguera, R. M. |
| author_sort |
Gutiérrez-Corbo, C. |
| title |
Reproduction in Trypanosomatids: Past and Present |
| title_short |
Reproduction in Trypanosomatids: Past and Present |
| title_full |
Reproduction in Trypanosomatids: Past and Present |
| title_fullStr |
Reproduction in Trypanosomatids: Past and Present |
| title_full_unstemmed |
Reproduction in Trypanosomatids: Past and Present |
| title_sort |
reproduction in trypanosomatids: past and present |
| publisher |
Multidisciplinary Digital Publishing Institute |
| publishDate |
2021 |
| url |
http://hdl.handle.net/10261/245153 http://dx.doi.org/10.13039/501100000780 http://dx.doi.org/10.13039/501100014180 http://dx.doi.org/10.13039/501100003329 |
| work_keys_str_mv |
AT gutierrezcorboc reproductionintrypanosomatidspastandpresent AT dominguezasenjobarbara reproductionintrypanosomatidspastandpresent AT martinezvalladaresmaria reproductionintrypanosomatidspastandpresent AT perezpertejoy reproductionintrypanosomatidspastandpresent AT garciaestradacarlos reproductionintrypanosomatidspastandpresent AT balanafoucerafael reproductionintrypanosomatidspastandpresent AT reguerarm reproductionintrypanosomatidspastandpresent |
| _version_ |
1777664091270152192 |