Triphenyltin alters lipid homeostasis in females of the ramshorn snail Marisa cornuarietis

Triphenyltin alters lipid homeostasis in females of the ramshorn snail Marisa cornuarietis

29 p., 3 tablas, 2 figuras y bibliografía

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Main Authors: Lyssimachou, Angeliki, Navarro, Juan Carlos, Bachmann, Jean, Porte Visa, Cinta
Format: artículo biblioteca
Language:English
Published: Elsevier 2009-05
Subjects:Fatty acids, Lipids, Molluscs, RXR, Triphenyltin,
Online Access:http://hdl.handle.net/10261/46519
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spelling dig-idaea-es-10261-465192020-07-03T12:32:25Z Triphenyltin alters lipid homeostasis in females of the ramshorn snail Marisa cornuarietis Lyssimachou, Angeliki Navarro, Juan Carlos Bachmann, Jean Porte Visa, Cinta Fatty acids Lipids Molluscs RXR Triphenyltin 29 p., 3 tablas, 2 figuras y bibliografía Molluscs are sensitive species to the toxic effects of organotin compounds, particularly to masculinization, and both, tributyltin (TBT) and triphenyltin (TPT) have been recently shown to bind to molluscs RXR. Being RXR is involved in lipid homeostasis, exposure to TPT would have an immediate effect on lipid homeostasis. To test this hypothesis, the ramshorn snail Marisa cornuarietis was exposed to environmentally relevant concentrations of TPT (30, 125, 500 ng/L as Sn) in a semi-static water regime for 7-days. Percentage of lipids and total fatty acid content decreased significantly in TPT-exposed females while the activity of peroxisomal acyl-CoA oxidase, involved in fatty acid catabolism, increased. In addition, fatty acid profiles (carbon chain length and unsaturation degree) were significantly altered in exposed females but not in males. This work highlights the ability of TPT to disrupt lipid metabolism in M. cornuarietis at environmentally realistic concentrations and the higher susceptibility of females in comparison to males. This study was supported by the European Union (COMPRENDO-Project, EVK1-CT-2002-00129) and the Spanish National Plan for Research (Project Ref CGL2005-02846). 2012-03-02T11:17:27Z 2012-03-02T11:17:27Z 2009-05 artículo http://purl.org/coar/resource_type/c_6501 Environmental pollution 157(5):1714-1720 (2009) 0269-7491 http://hdl.handle.net/10261/46519 10.1016/j.envpol.2008.12.013 1873-6424 en http://dx.doi.org/10.1016/j.envpol.2008.12.013 open Elsevier
institution IDAEA ES
collection DSpace
country España
countrycode ES
component Bibliográfico
access En linea
databasecode dig-idaea-es
tag biblioteca
region Europa del Sur
libraryname Biblioteca del IDAEA España
language English
topic Fatty acids
Lipids
Molluscs
RXR
Triphenyltin
Fatty acids
Lipids
Molluscs
RXR
Triphenyltin
spellingShingle Fatty acids
Lipids
Molluscs
RXR
Triphenyltin
Fatty acids
Lipids
Molluscs
RXR
Triphenyltin
Lyssimachou, Angeliki
Navarro, Juan Carlos
Bachmann, Jean
Porte Visa, Cinta
Triphenyltin alters lipid homeostasis in females of the ramshorn snail Marisa cornuarietis
description 29 p., 3 tablas, 2 figuras y bibliografía
format artículo
topic_facet Fatty acids
Lipids
Molluscs
RXR
Triphenyltin
author Lyssimachou, Angeliki
Navarro, Juan Carlos
Bachmann, Jean
Porte Visa, Cinta
author_facet Lyssimachou, Angeliki
Navarro, Juan Carlos
Bachmann, Jean
Porte Visa, Cinta
author_sort Lyssimachou, Angeliki
title Triphenyltin alters lipid homeostasis in females of the ramshorn snail Marisa cornuarietis
title_short Triphenyltin alters lipid homeostasis in females of the ramshorn snail Marisa cornuarietis
title_full Triphenyltin alters lipid homeostasis in females of the ramshorn snail Marisa cornuarietis
title_fullStr Triphenyltin alters lipid homeostasis in females of the ramshorn snail Marisa cornuarietis
title_full_unstemmed Triphenyltin alters lipid homeostasis in females of the ramshorn snail Marisa cornuarietis
title_sort triphenyltin alters lipid homeostasis in females of the ramshorn snail marisa cornuarietis
publisher Elsevier
publishDate 2009-05
url http://hdl.handle.net/10261/46519
work_keys_str_mv AT lyssimachouangeliki triphenyltinalterslipidhomeostasisinfemalesoftheramshornsnailmarisacornuarietis
AT navarrojuancarlos triphenyltinalterslipidhomeostasisinfemalesoftheramshornsnailmarisacornuarietis
AT bachmannjean triphenyltinalterslipidhomeostasisinfemalesoftheramshornsnailmarisacornuarietis
AT portevisacinta triphenyltinalterslipidhomeostasisinfemalesoftheramshornsnailmarisacornuarietis
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