Hydroxychloroquine for Early Treatment of Adults With Mild Coronavirus Disease 2019: A Randomized, Controlled Trial
No effective treatments for coronavirus disease 2019 (COVID-19) exist. We aimed to determine whether early treatment with hydroxychloroquine (HCQ) would be efficacious for outpatients with COVID-19.
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| Main Authors: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
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| Format: | artículo biblioteca |
| Language: | English |
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Oxford University Press
2021-12-01
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| Subjects: | COVID-19, SARS-CoV-2, Hydroxychloroquine, Randomized controlled trial, Therapy, |
| Online Access: | http://hdl.handle.net/10261/259501 https://api.elsevier.com/content/abstract/scopus_id/85122546667 |
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dig-idaea-es-10261-2595012024-05-15T20:38:52Z Hydroxychloroquine for Early Treatment of Adults With Mild Coronavirus Disease 2019: A Randomized, Controlled Trial Mitjà, Oriol Corbacho-Monné, Marc Ubals, Maria Tebé, Cristian Peñafiel, Judith Tobías, Aurelio Ballana, Ester Alemany, Andrea Riera-Martí, Núria Pérez, Carla A Suñer, Clara Laporte, Pep Admella, Pol Mitjà, Jordi Clua, Mireia Bertran, Laia Sarquella, Maria Gavilán, Sergi Ara, Jordi Argimon, Josep M Casabona, Jordi Cuatrecasas, Gabriel Cañadas, Paz Elizalde-Torrent, Aleix Fabregat, Robert Farré, Magí Forcada, Anna Flores-Mateo, Gemma Muntada, Esteve Nadal, Núria Narejos, Silvia Nieto, Aroa Prat, Nuria Puig, Jordi Quiñones, Carles Reyes-Ureña, Juliana Ramírez-Viaplana, Ferran Ruiz, Lidia Riveira-Muñoz, Eva Sierra, Alba Velasco, César Vivanco-Hidalgo, Rosa M. Sentís, Alexis G-Beiras, Camila Clotet, Bonaventura Vall-Mayans, Martí 0000-0002-8132-5645 COVID-19 SARS-CoV-2 Hydroxychloroquine Randomized controlled trial Therapy No effective treatments for coronavirus disease 2019 (COVID-19) exist. We aimed to determine whether early treatment with hydroxychloroquine (HCQ) would be efficacious for outpatients with COVID-19. The authors thank Gerard Carot-Sans, PhD, for providing medical writing support during the revisions of the subsequent drafts of the manuscript; the personnel from the Fights Aids and Infectious Diseases Foundation for their support in administration, human resources and supply chain management; Eric Ubals (Pierce AB) and Òscar Palao (Opentic) for website and database management; Óscar Camps and OpenArms nongovernmental organization for nursing home operations; and Anna Valentí and the Hospital Germans Trias i Pujol Human Resources Department for telephone monitoring. We thank Consorci Sanitari del Maresme, Centre Sociosanitari El Carme, l'Hospital General de Granollers and occupational hazards department of Hospital Germans Trias i Pujol for their contribution with patient enrollment. We are very grateful to Marc Clotet and Natalia Sánchez who coordinated the JoEmCorono crowd-funding campaign. We thank the Hospital Germans Trias Pujol Institutional Review Board and the Spanish Agency of Medicines and Medical Devices for their prompt action for consideration and approvals to the protocol. Financial support. This work was mainly supported by the crowd-funding campaign JoEmCorono (https://www.yomecorono.com/) with contributions from more than 72 000 citizens and corporations. The study also received financial support from Laboratorios Rubió, Laboratorios Gebro Pharma, Zurich Seguros, SYNLAB Barcelona, and Generalitat de Catalunya. Laboratorios Rubió also contributed to the study with the required doses of hydroxychloroquine (Dolquine®). Foundation Dorneur partly funded lab equipment at Irsi-Caixa. Peer reviewed 2022-02-02T09:09:52Z 2022-02-02T09:09:52Z 2021-12-01 artículo http://purl.org/coar/resource_type/c_6501 Clinical Infectious Diseases 73 (11): e4073–e4081 (2021) http://hdl.handle.net/10261/259501 10.1093/cid/ciaa1009 32674126 2-s2.0-85122546667 https://api.elsevier.com/content/abstract/scopus_id/85122546667 en Clinical infectious diseases : an official publication of the Infectious Diseases Society of America Publisher's version https://doi.org/10.1093/cid/ciaa1009 Sí open Oxford University Press |
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| libraryname |
Biblioteca del IDAEA España |
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| topic |
COVID-19 SARS-CoV-2 Hydroxychloroquine Randomized controlled trial Therapy COVID-19 SARS-CoV-2 Hydroxychloroquine Randomized controlled trial Therapy |
| spellingShingle |
COVID-19 SARS-CoV-2 Hydroxychloroquine Randomized controlled trial Therapy COVID-19 SARS-CoV-2 Hydroxychloroquine Randomized controlled trial Therapy Mitjà, Oriol Corbacho-Monné, Marc Ubals, Maria Tebé, Cristian Peñafiel, Judith Tobías, Aurelio Ballana, Ester Alemany, Andrea Riera-Martí, Núria Pérez, Carla A Suñer, Clara Laporte, Pep Admella, Pol Mitjà, Jordi Clua, Mireia Bertran, Laia Sarquella, Maria Gavilán, Sergi Ara, Jordi Argimon, Josep M Casabona, Jordi Cuatrecasas, Gabriel Cañadas, Paz Elizalde-Torrent, Aleix Fabregat, Robert Farré, Magí Forcada, Anna Flores-Mateo, Gemma Muntada, Esteve Nadal, Núria Narejos, Silvia Nieto, Aroa Prat, Nuria Puig, Jordi Quiñones, Carles Reyes-Ureña, Juliana Ramírez-Viaplana, Ferran Ruiz, Lidia Riveira-Muñoz, Eva Sierra, Alba Velasco, César Vivanco-Hidalgo, Rosa M. Sentís, Alexis G-Beiras, Camila Clotet, Bonaventura Vall-Mayans, Martí Hydroxychloroquine for Early Treatment of Adults With Mild Coronavirus Disease 2019: A Randomized, Controlled Trial |
| description |
No effective treatments for coronavirus disease 2019 (COVID-19) exist. We aimed to determine whether early treatment with hydroxychloroquine (HCQ) would be efficacious for outpatients with COVID-19. |
| author2 |
0000-0002-8132-5645 |
| author_facet |
0000-0002-8132-5645 Mitjà, Oriol Corbacho-Monné, Marc Ubals, Maria Tebé, Cristian Peñafiel, Judith Tobías, Aurelio Ballana, Ester Alemany, Andrea Riera-Martí, Núria Pérez, Carla A Suñer, Clara Laporte, Pep Admella, Pol Mitjà, Jordi Clua, Mireia Bertran, Laia Sarquella, Maria Gavilán, Sergi Ara, Jordi Argimon, Josep M Casabona, Jordi Cuatrecasas, Gabriel Cañadas, Paz Elizalde-Torrent, Aleix Fabregat, Robert Farré, Magí Forcada, Anna Flores-Mateo, Gemma Muntada, Esteve Nadal, Núria Narejos, Silvia Nieto, Aroa Prat, Nuria Puig, Jordi Quiñones, Carles Reyes-Ureña, Juliana Ramírez-Viaplana, Ferran Ruiz, Lidia Riveira-Muñoz, Eva Sierra, Alba Velasco, César Vivanco-Hidalgo, Rosa M. Sentís, Alexis G-Beiras, Camila Clotet, Bonaventura Vall-Mayans, Martí |
| format |
artículo |
| topic_facet |
COVID-19 SARS-CoV-2 Hydroxychloroquine Randomized controlled trial Therapy |
| author |
Mitjà, Oriol Corbacho-Monné, Marc Ubals, Maria Tebé, Cristian Peñafiel, Judith Tobías, Aurelio Ballana, Ester Alemany, Andrea Riera-Martí, Núria Pérez, Carla A Suñer, Clara Laporte, Pep Admella, Pol Mitjà, Jordi Clua, Mireia Bertran, Laia Sarquella, Maria Gavilán, Sergi Ara, Jordi Argimon, Josep M Casabona, Jordi Cuatrecasas, Gabriel Cañadas, Paz Elizalde-Torrent, Aleix Fabregat, Robert Farré, Magí Forcada, Anna Flores-Mateo, Gemma Muntada, Esteve Nadal, Núria Narejos, Silvia Nieto, Aroa Prat, Nuria Puig, Jordi Quiñones, Carles Reyes-Ureña, Juliana Ramírez-Viaplana, Ferran Ruiz, Lidia Riveira-Muñoz, Eva Sierra, Alba Velasco, César Vivanco-Hidalgo, Rosa M. Sentís, Alexis G-Beiras, Camila Clotet, Bonaventura Vall-Mayans, Martí |
| author_sort |
Mitjà, Oriol |
| title |
Hydroxychloroquine for Early Treatment of Adults With Mild Coronavirus Disease 2019: A Randomized, Controlled Trial |
| title_short |
Hydroxychloroquine for Early Treatment of Adults With Mild Coronavirus Disease 2019: A Randomized, Controlled Trial |
| title_full |
Hydroxychloroquine for Early Treatment of Adults With Mild Coronavirus Disease 2019: A Randomized, Controlled Trial |
| title_fullStr |
Hydroxychloroquine for Early Treatment of Adults With Mild Coronavirus Disease 2019: A Randomized, Controlled Trial |
| title_full_unstemmed |
Hydroxychloroquine for Early Treatment of Adults With Mild Coronavirus Disease 2019: A Randomized, Controlled Trial |
| title_sort |
hydroxychloroquine for early treatment of adults with mild coronavirus disease 2019: a randomized, controlled trial |
| publisher |
Oxford University Press |
| publishDate |
2021-12-01 |
| url |
http://hdl.handle.net/10261/259501 https://api.elsevier.com/content/abstract/scopus_id/85122546667 |
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