Evidence of endocrine alteration in the red mullet, Mullus barbatus from the NW Mediterranean
9 pages, 4 figures, 4 tables.
Saved in:
| Main Authors: | , , , , |
|---|---|
| Format: | artículo biblioteca |
| Language: | English |
| Published: |
Elsevier
2006-05-01
|
| Subjects: | Mullus barbatus, Alkylphenols, Uridine diphosphate-glucuronosyltransferase, Ovarian P-450 aromatase, 17beta-hydroxysteroid dehydrogenase, Intersex, |
| Online Access: | http://hdl.handle.net/10261/11838 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| id |
dig-idaea-es-10261-11838 |
|---|---|
| record_format |
koha |
| spelling |
dig-idaea-es-10261-118382020-07-03T12:32:22Z Evidence of endocrine alteration in the red mullet, Mullus barbatus from the NW Mediterranean Martin-Skilton, Rebeca Lavado Parra, Ramón Thibaut, Rémi Minier, Christophe Porte Visa, Cinta Mullus barbatus Alkylphenols Uridine diphosphate-glucuronosyltransferase Ovarian P-450 aromatase 17beta-hydroxysteroid dehydrogenase Intersex 9 pages, 4 figures, 4 tables. Red mullet (Mullus barbatus) were collected from different sampling sites (NW Mediterranean) in spring and autumn, with the aim of assessing potential alterations of the endocrine system. Alkylphenols were measured in fish bile as an indicator of estrogenic exposure. Key enzymatic activities involved in both synthesis (ovarian 17β-hydroxysteroid dehydrogenases and P450 aromatase) and metabolism of steroids were assessed together with histological alterations of the gonads. During the spring sampling, delayed gamete maturation, intersexuality, fibrosis, and depressed ovarian P450 aromatase activity were observed in organisms from the most polluted sites. During the autumn sampling, those effects were less evident, indicating that fish might be more susceptible to endocrine disrupting chemicals during the reproductive period. Nonetheless, enhanced glucuronidation of testosterone and estradiol was observed. Overall, this work provides first evidences of significant alterations in the endocrine system of red mullet from highly impacted areas in the NW Mediterranean. This work was partially supported by the EC Project ENVK3-CT-2000-00025. R.M.-S. acknowledges a predoctoral fellowship from the Spanish Government. Dr. Rémi Thibaut acknowledges a I3P contract from the Spanish Government. Peer reviewed 2009-03-25T12:12:54Z 2009-03-25T12:12:54Z 2006-05-01 artículo http://purl.org/coar/resource_type/c_6501 Envirnmental Pollution 141(1):60-68(2006) 0269-7491 http://hdl.handle.net/10261/11838 10.1016/j.envpol.2005.08.016 en http://dx.doi.org/10.1016/j.envpol.2005.08.016 none 19968 bytes application/msword Elsevier |
| institution |
IDAEA ES |
| collection |
DSpace |
| country |
España |
| countrycode |
ES |
| component |
Bibliográfico |
| access |
En linea |
| databasecode |
dig-idaea-es |
| tag |
biblioteca |
| region |
Europa del Sur |
| libraryname |
Biblioteca del IDAEA España |
| language |
English |
| topic |
Mullus barbatus Alkylphenols Uridine diphosphate-glucuronosyltransferase Ovarian P-450 aromatase 17beta-hydroxysteroid dehydrogenase Intersex Mullus barbatus Alkylphenols Uridine diphosphate-glucuronosyltransferase Ovarian P-450 aromatase 17beta-hydroxysteroid dehydrogenase Intersex |
| spellingShingle |
Mullus barbatus Alkylphenols Uridine diphosphate-glucuronosyltransferase Ovarian P-450 aromatase 17beta-hydroxysteroid dehydrogenase Intersex Mullus barbatus Alkylphenols Uridine diphosphate-glucuronosyltransferase Ovarian P-450 aromatase 17beta-hydroxysteroid dehydrogenase Intersex Martin-Skilton, Rebeca Lavado Parra, Ramón Thibaut, Rémi Minier, Christophe Porte Visa, Cinta Evidence of endocrine alteration in the red mullet, Mullus barbatus from the NW Mediterranean |
| description |
9 pages, 4 figures, 4 tables. |
| format |
artículo |
| topic_facet |
Mullus barbatus Alkylphenols Uridine diphosphate-glucuronosyltransferase Ovarian P-450 aromatase 17beta-hydroxysteroid dehydrogenase Intersex |
| author |
Martin-Skilton, Rebeca Lavado Parra, Ramón Thibaut, Rémi Minier, Christophe Porte Visa, Cinta |
| author_facet |
Martin-Skilton, Rebeca Lavado Parra, Ramón Thibaut, Rémi Minier, Christophe Porte Visa, Cinta |
| author_sort |
Martin-Skilton, Rebeca |
| title |
Evidence of endocrine alteration in the red mullet, Mullus barbatus from the NW Mediterranean |
| title_short |
Evidence of endocrine alteration in the red mullet, Mullus barbatus from the NW Mediterranean |
| title_full |
Evidence of endocrine alteration in the red mullet, Mullus barbatus from the NW Mediterranean |
| title_fullStr |
Evidence of endocrine alteration in the red mullet, Mullus barbatus from the NW Mediterranean |
| title_full_unstemmed |
Evidence of endocrine alteration in the red mullet, Mullus barbatus from the NW Mediterranean |
| title_sort |
evidence of endocrine alteration in the red mullet, mullus barbatus from the nw mediterranean |
| publisher |
Elsevier |
| publishDate |
2006-05-01 |
| url |
http://hdl.handle.net/10261/11838 |
| work_keys_str_mv |
AT martinskiltonrebeca evidenceofendocrinealterationintheredmulletmullusbarbatusfromthenwmediterranean AT lavadoparraramon evidenceofendocrinealterationintheredmulletmullusbarbatusfromthenwmediterranean AT thibautremi evidenceofendocrinealterationintheredmulletmullusbarbatusfromthenwmediterranean AT minierchristophe evidenceofendocrinealterationintheredmulletmullusbarbatusfromthenwmediterranean AT portevisacinta evidenceofendocrinealterationintheredmulletmullusbarbatusfromthenwmediterranean |
| _version_ |
1777669145516572672 |