Multi-residue analytical methods using LC-tandem MS for the determination of pharmaceuticals in environmental and wastewater samples: a review
12 pages, 3 figures, 2 tables.
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Format: | artículo biblioteca |
Language: | English |
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Springer
2006-10-01
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Subjects: | Multi-residue methods, Pharmaceuticals, Environmental analysis, Tandem mass spectrometry, |
Online Access: | http://hdl.handle.net/10261/11822 |
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dig-idaea-es-10261-118222009-03-25T23:00:00Z Multi-residue analytical methods using LC-tandem MS for the determination of pharmaceuticals in environmental and wastewater samples: a review Gros, Meritxell Petrovic, Mira Barceló, Damià Multi-residue methods Pharmaceuticals Environmental analysis Tandem mass spectrometry 12 pages, 3 figures, 2 tables. Multi-residue analytical methodologies are becoming the preferred and required tools against single group analysis, as they provide wider knowledge about the occurrence of pharmaceuticals in the environment necessary for further study of their removal, partition and ultimate fate. However, simultaneous analysis of compounds from different groups with quite different physico-chemical characteristics requires a compromise in the selection of experimental conditions, which in some cases are not the best conditions for all the analytes studied. In this article, an overview of analytical methodologies focusing on the simultaneous determination of acidic, neutral and basic compounds belonging to different therapeutical classes is presented. The state-of-the-art of LC-MS/MS for multi-class analysis is reviewed, highlighting the specific requirements for such analysis This work was financially supported by the European Union EMCO project (INCO-CT-2004-509188) and by the Spanish Ministerio de Ciencia y Tecnología (EVITA project- CTM2004-06265-C03-01). M. Gros acknowledges the grant from the Spanish MCyT (CTM2004-06265-C03-01). Peer reviewed 2009-03-25T09:02:26Z 2009-03-25T09:02:26Z 2006-10-01 artículo http://purl.org/coar/resource_type/c_6501 Analytical and Bioanalytical Chemistry 386(4):941-952 (2006) 1618-2650 (Online) 1618-2642 (Print) http://hdl.handle.net/10261/11822 10.1007/s00216-006-0586-z en http://dx.doi.org/10.1007/s00216-006-0586-z none 19968 bytes application/msword Springer |
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Multi-residue methods Pharmaceuticals Environmental analysis Tandem mass spectrometry Multi-residue methods Pharmaceuticals Environmental analysis Tandem mass spectrometry |
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Multi-residue methods Pharmaceuticals Environmental analysis Tandem mass spectrometry Multi-residue methods Pharmaceuticals Environmental analysis Tandem mass spectrometry Gros, Meritxell Petrovic, Mira Barceló, Damià Multi-residue analytical methods using LC-tandem MS for the determination of pharmaceuticals in environmental and wastewater samples: a review |
description |
12 pages, 3 figures, 2 tables. |
format |
artículo |
topic_facet |
Multi-residue methods Pharmaceuticals Environmental analysis Tandem mass spectrometry |
author |
Gros, Meritxell Petrovic, Mira Barceló, Damià |
author_facet |
Gros, Meritxell Petrovic, Mira Barceló, Damià |
author_sort |
Gros, Meritxell |
title |
Multi-residue analytical methods using LC-tandem MS for the determination of pharmaceuticals in environmental and wastewater samples: a review |
title_short |
Multi-residue analytical methods using LC-tandem MS for the determination of pharmaceuticals in environmental and wastewater samples: a review |
title_full |
Multi-residue analytical methods using LC-tandem MS for the determination of pharmaceuticals in environmental and wastewater samples: a review |
title_fullStr |
Multi-residue analytical methods using LC-tandem MS for the determination of pharmaceuticals in environmental and wastewater samples: a review |
title_full_unstemmed |
Multi-residue analytical methods using LC-tandem MS for the determination of pharmaceuticals in environmental and wastewater samples: a review |
title_sort |
multi-residue analytical methods using lc-tandem ms for the determination of pharmaceuticals in environmental and wastewater samples: a review |
publisher |
Springer |
publishDate |
2006-10-01 |
url |
http://hdl.handle.net/10261/11822 |
work_keys_str_mv |
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1777669145239748608 |