Are obesity and physical fitness associated with cardiovascular disease risk in adolescents with Down syndrome? The longitudinal UP&DOWN study

Are obesity and physical fitness associated with cardiovascular disease risk in adolescents with Down syndrome? The longitudinal UP&DOWN study

[Introduction] The aims of this study were to examine cross-sectional, and longitudinal association of different measures of obesity and physical fitness with cardiovascular disease (CVD) risk factors in adolescents with Down syndrome.

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Main Authors: Izquierdo-Gómez, Rocío, Esteban-Cornejo, Irene, Cabanas-Sánchez, Verónica, Marcos, Ascensión, Gómez Martínez, Sonia, Castro-Piñero, José, Veiga, Óscar, UP&DOWN Study Group
Other Authors: Ministerio de Ciencia, Innovación y Universidades (España)
Format: artículo biblioteca
Language:English
Published: Taylor & Francis 2023
Online Access:http://hdl.handle.net/10261/341132
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spelling dig-ictan-es-10261-3411322023-12-21T10:14:17Z Are obesity and physical fitness associated with cardiovascular disease risk in adolescents with Down syndrome? The longitudinal UP&DOWN study Izquierdo-Gómez, Rocío Esteban-Cornejo, Irene Cabanas-Sánchez, Verónica Marcos, Ascensión Gómez Martínez, Sonia Castro-Piñero, José Veiga, Óscar UP&DOWN Study Group Ministerio de Ciencia, Innovación y Universidades (España) Agencia Estatal de Investigación (España) Ministerio de Ciencia e Innovación (España) [Introduction] The aims of this study were to examine cross-sectional, and longitudinal association of different measures of obesity and physical fitness with cardiovascular disease (CVD) risk factors in adolescents with Down syndrome. [Methods] Longitudinal analysis included 90 adolescents with Down syndrome. Obesity and physical fitness were measured following the ALPHA battery. Blood pressure and blood samplings (glucose, total cholesterol, high-density lipoprotein cholesterol, and serum lipid triglycerides levels (mg/dl) were determinated. [Results] In cross-sectional analyses, obesity was positively associated with single CVD risk factors and CVD risk factor index (all p < .05). In the prospective analyses, obesity was not associated with single CVD risk factors, but components of physical fitness at baseline impact in some single CVD risk factors (all p < .05). [Conclusion] Obesity might be more strongly related to current cardiovascular-health, while components of physical fitness might be more related to future cardiovascular-health in adolescents with Down syndrome. This study was supported by the DEP 2010-21662-C04-00 grant from the National Plan for Research, Development and Innovation (R+D+i) MICINN. VCS is supported by the Spanish Ministry of Science, Innovation and Universities (IJC2018-038008-I). IEC is supported by the Spanish Ministry of Science and Innovation (RYC2019-027287-I). Peer reviewed 2023-12-21T10:14:17Z 2023-12-21T10:14:17Z 2023 artículo Journal of Intellectual and Developmental Disability 48(3): 247-259 (2023) http://hdl.handle.net/10261/341132 10.3109/13668250.2023.2188876 1469-9532 en #PLACEHOLDER_PARENT_METADATA_VALUE# #PLACEHOLDER_PARENT_METADATA_VALUE# info:eu-repo/grantAgreement/AEI//IJC2018-038008-I info:eu-repo/grantAgreement/AEI//RYC2019-027287-I https://doi.org/10.3109/13668250.2023.2188876 Sí none Taylor & Francis
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libraryname Biblioteca del ICTAN España
language English
description [Introduction] The aims of this study were to examine cross-sectional, and longitudinal association of different measures of obesity and physical fitness with cardiovascular disease (CVD) risk factors in adolescents with Down syndrome.
author2 Ministerio de Ciencia, Innovación y Universidades (España)
author_facet Ministerio de Ciencia, Innovación y Universidades (España)
Izquierdo-Gómez, Rocío
Esteban-Cornejo, Irene
Cabanas-Sánchez, Verónica
Marcos, Ascensión
Gómez Martínez, Sonia
Castro-Piñero, José
Veiga, Óscar
UP&DOWN Study Group
format artículo
author Izquierdo-Gómez, Rocío
Esteban-Cornejo, Irene
Cabanas-Sánchez, Verónica
Marcos, Ascensión
Gómez Martínez, Sonia
Castro-Piñero, José
Veiga, Óscar
UP&DOWN Study Group
spellingShingle Izquierdo-Gómez, Rocío
Esteban-Cornejo, Irene
Cabanas-Sánchez, Verónica
Marcos, Ascensión
Gómez Martínez, Sonia
Castro-Piñero, José
Veiga, Óscar
UP&DOWN Study Group
Are obesity and physical fitness associated with cardiovascular disease risk in adolescents with Down syndrome? The longitudinal UP&DOWN study
author_sort Izquierdo-Gómez, Rocío
title Are obesity and physical fitness associated with cardiovascular disease risk in adolescents with Down syndrome? The longitudinal UP&DOWN study
title_short Are obesity and physical fitness associated with cardiovascular disease risk in adolescents with Down syndrome? The longitudinal UP&DOWN study
title_full Are obesity and physical fitness associated with cardiovascular disease risk in adolescents with Down syndrome? The longitudinal UP&DOWN study
title_fullStr Are obesity and physical fitness associated with cardiovascular disease risk in adolescents with Down syndrome? The longitudinal UP&DOWN study
title_full_unstemmed Are obesity and physical fitness associated with cardiovascular disease risk in adolescents with Down syndrome? The longitudinal UP&DOWN study
title_sort are obesity and physical fitness associated with cardiovascular disease risk in adolescents with down syndrome? the longitudinal up&down study
publisher Taylor & Francis
publishDate 2023
url http://hdl.handle.net/10261/341132
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