Cardiorespiratory fitness cutoff points for early detection of present and future cardiovascular risk in children: A 2-year follow-up study
On behalf of the UP&DOWN Study Group.
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Elsevier
2017
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Online Access: | http://hdl.handle.net/10261/171275 http://dx.doi.org/10.13039/501100004837 |
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dig-ictan-es-10261-1712752021-06-22T12:50:42Z Cardiorespiratory fitness cutoff points for early detection of present and future cardiovascular risk in children: A 2-year follow-up study Castro-Piñero, José Perez-Bey, Alejandro Segura-Jiménez, Víctor Aparicio, Virginia A. Gómez Martínez, Sonia Izquierdo-Gómez, Rocío Marcos, Ascensión Ruiz, Jonatan R. Veiga, Óscar Bandres, Fernando Martínez Gómez, D. Carbonell-Baeza, Ana Santiago, Catalina Nova, Esther Díaz, L. E. Zapatera, Belén Veses, Ana M. Hernández, Aurora Gheorghe, Alina Mora-Vicente, Jesus Gonzalez-Montesinos, Jose L. Conde-Caveda, Julio Ortega, F. B. Padilla-Moledo, Carmen Chillón, P. Rosario Fernández-Santos, Jorge del Gonzalez Galo, Ana Bellvis Guerra, Gonzalo Delgado Alfonso, Alvaro Parrilla, Fernando Gomez, Roque Gavala, Juan Villagra, H. Ariel Campo, Juan del Cordente, Carlos Díaz, Mario Tejero-González, Carlos M. Acha, Aitor Moya, J. M. Sanz, Alberto Martínez Gómez, D. Cabanas-Sánchez, Verónica Rodriguez-Romo, Gabriel Garcia-Cervantes, Laura Esteban-Cornejo, Irene Lucia, Alejandro Gómez-Gallego, Félix Ministerio de Ciencia e Innovación (España) Ministerio de Educación (España) On behalf of the UP&DOWN Study Group. [Objective]: To examine the association between cardiorespiratory fitness (CRF) at baseline and cardiovascular disease (CVD) risk in 6- to 10-year-olds (cross-sectional) and 2 years later (8- to 12-year-olds [longitudinal]) and whether changes with age in CRF are associated with CVD risk in children aged 8 to 12 years. [Patients and Methods]: Spanish primary schoolchildren (n=236) aged 6 to 10 years participated at baseline. Of the 23 participating primary schools, 22% (n=5) were private schools and 78% (n=18) were public schools. The dropout rate at 2-year follow-up was 9.7% (n=23). The 20-m shuttle run test was used to estimate CRF. The CVD risk score was computed as the mean of 5 CVD risk factor standardized scores: sum of 2 skinfolds, systolic blood pressure, insulin/glucose, triglycerides, and total cholesterol/high-density lipoprotein cholesterol. [Results]: At baseline, CRF was inversely associated with single CVD risk factors (all P<.05) and CVD risk score at baseline and follow-up (P<.001). Cardiorespiratory fitness cutoff points of 39.0 mL/kg per minute or greater in boys and 37.5 mL/kg per minute or greater in girls are discriminative to identify CVD risk in childhood (area under the curve, >0.85; P<.001) and to predict CVD risk 2 years later (P=.004). Persistent low CRF or the decline of CRF from 6-10 to 8-12 years of age is associated with increased CVD risk at age 8 to 12 years (P<.001). [Conclusion]: During childhood, CRF is a strong predictor of CVD risk and should be monitored to identify children with potential CVD risk. This work was supported by grant DEP 2010-21662-C04-00 (DEP 2010-21662-C04-01: DEP 2010-21662-C04-02: DEP 2010-21662-C04-03: DEP 2010-21662-C04-04) from the National Plan for Research: Development and Innovation (R+D+i) MICINN and by grant FPU15/05337 from the Spanish Ministry of Education. Peer Reviewed 2018-10-19T10:46:18Z 2018-10-19T10:46:18Z 2017 2018-10-19T10:46:19Z artículo http://purl.org/coar/resource_type/c_6501 doi: 10.1016/j.mayocp.2017.09.003 e-issn: 1942-5546 issn: 0025-6196 Mayo Clinic Proceedings 92(12): 1753-1762 (2017) http://hdl.handle.net/10261/171275 10.1016/j.mayocp.2017.09.003 http://dx.doi.org/10.13039/501100004837 29157533 Sí none Elsevier |
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On behalf of the UP&DOWN Study Group. |
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Ministerio de Ciencia e Innovación (España) |
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Ministerio de Ciencia e Innovación (España) Castro-Piñero, José Perez-Bey, Alejandro Segura-Jiménez, Víctor Aparicio, Virginia A. Gómez Martínez, Sonia Izquierdo-Gómez, Rocío Marcos, Ascensión Ruiz, Jonatan R. Veiga, Óscar Bandres, Fernando Martínez Gómez, D. Carbonell-Baeza, Ana Santiago, Catalina Nova, Esther Díaz, L. E. Zapatera, Belén Veses, Ana M. Hernández, Aurora Gheorghe, Alina Mora-Vicente, Jesus Gonzalez-Montesinos, Jose L. Conde-Caveda, Julio Ortega, F. B. Padilla-Moledo, Carmen Chillón, P. Rosario Fernández-Santos, Jorge del Gonzalez Galo, Ana Bellvis Guerra, Gonzalo Delgado Alfonso, Alvaro Parrilla, Fernando Gomez, Roque Gavala, Juan Villagra, H. Ariel Campo, Juan del Cordente, Carlos Díaz, Mario Tejero-González, Carlos M. Acha, Aitor Moya, J. M. Sanz, Alberto Martínez Gómez, D. Cabanas-Sánchez, Verónica Rodriguez-Romo, Gabriel Garcia-Cervantes, Laura Esteban-Cornejo, Irene Lucia, Alejandro Gómez-Gallego, Félix |
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Castro-Piñero, José Perez-Bey, Alejandro Segura-Jiménez, Víctor Aparicio, Virginia A. Gómez Martínez, Sonia Izquierdo-Gómez, Rocío Marcos, Ascensión Ruiz, Jonatan R. Veiga, Óscar Bandres, Fernando Martínez Gómez, D. Carbonell-Baeza, Ana Santiago, Catalina Nova, Esther Díaz, L. E. Zapatera, Belén Veses, Ana M. Hernández, Aurora Gheorghe, Alina Mora-Vicente, Jesus Gonzalez-Montesinos, Jose L. Conde-Caveda, Julio Ortega, F. B. Padilla-Moledo, Carmen Chillón, P. Rosario Fernández-Santos, Jorge del Gonzalez Galo, Ana Bellvis Guerra, Gonzalo Delgado Alfonso, Alvaro Parrilla, Fernando Gomez, Roque Gavala, Juan Villagra, H. Ariel Campo, Juan del Cordente, Carlos Díaz, Mario Tejero-González, Carlos M. Acha, Aitor Moya, J. M. Sanz, Alberto Martínez Gómez, D. Cabanas-Sánchez, Verónica Rodriguez-Romo, Gabriel Garcia-Cervantes, Laura Esteban-Cornejo, Irene Lucia, Alejandro Gómez-Gallego, Félix |
spellingShingle |
Castro-Piñero, José Perez-Bey, Alejandro Segura-Jiménez, Víctor Aparicio, Virginia A. Gómez Martínez, Sonia Izquierdo-Gómez, Rocío Marcos, Ascensión Ruiz, Jonatan R. Veiga, Óscar Bandres, Fernando Martínez Gómez, D. Carbonell-Baeza, Ana Santiago, Catalina Nova, Esther Díaz, L. E. Zapatera, Belén Veses, Ana M. Hernández, Aurora Gheorghe, Alina Mora-Vicente, Jesus Gonzalez-Montesinos, Jose L. Conde-Caveda, Julio Ortega, F. B. Padilla-Moledo, Carmen Chillón, P. Rosario Fernández-Santos, Jorge del Gonzalez Galo, Ana Bellvis Guerra, Gonzalo Delgado Alfonso, Alvaro Parrilla, Fernando Gomez, Roque Gavala, Juan Villagra, H. Ariel Campo, Juan del Cordente, Carlos Díaz, Mario Tejero-González, Carlos M. Acha, Aitor Moya, J. M. Sanz, Alberto Martínez Gómez, D. Cabanas-Sánchez, Verónica Rodriguez-Romo, Gabriel Garcia-Cervantes, Laura Esteban-Cornejo, Irene Lucia, Alejandro Gómez-Gallego, Félix Cardiorespiratory fitness cutoff points for early detection of present and future cardiovascular risk in children: A 2-year follow-up study |
author_sort |
Castro-Piñero, José |
title |
Cardiorespiratory fitness cutoff points for early detection of present and future cardiovascular risk in children: A 2-year follow-up study |
title_short |
Cardiorespiratory fitness cutoff points for early detection of present and future cardiovascular risk in children: A 2-year follow-up study |
title_full |
Cardiorespiratory fitness cutoff points for early detection of present and future cardiovascular risk in children: A 2-year follow-up study |
title_fullStr |
Cardiorespiratory fitness cutoff points for early detection of present and future cardiovascular risk in children: A 2-year follow-up study |
title_full_unstemmed |
Cardiorespiratory fitness cutoff points for early detection of present and future cardiovascular risk in children: A 2-year follow-up study |
title_sort |
cardiorespiratory fitness cutoff points for early detection of present and future cardiovascular risk in children: a 2-year follow-up study |
publisher |
Elsevier |
publishDate |
2017 |
url |
http://hdl.handle.net/10261/171275 http://dx.doi.org/10.13039/501100004837 |
work_keys_str_mv |
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