PAH Metabolites in Fish and Invertebrates: Analysis and Endocrine Disruptive Potential
24 pages, 2 figures, 1 table
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Bentham Science Publishers
2017
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Subjects: | Oxidized PAHs, Metabolism, Endocrine alteration, Analysis, |
Online Access: | http://hdl.handle.net/10261/159680 |
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dig-icm-es-10261-1596802020-12-21T08:27:37Z PAH Metabolites in Fish and Invertebrates: Analysis and Endocrine Disruptive Potential Fernandes, Denise Marqueño, Anna Porte Visa, Cinta Solé, Montserrat Oxidized PAHs Metabolism Endocrine alteration Analysis 24 pages, 2 figures, 1 table This chapter describes the metabolism of PAHs to oxidized and conjugated metabolites by both fish and invertebrates. So far, a wide range of metabolites have been described and a number of studies have alerted for the potential of phenol and quinone derivatives, as well as other reactive intermediates, to exert toxicity in early life stages of fish and reproductive disorders in adults. The endocrine disruptive properties have been mainly related to action at the receptor level, due to structural similarities of PAH and their metabolites with natural hormones, and also to interaction with key steroidogenic enzymes, which are present in vertebrate and invertebrate groups. The fast development of new analytical techniques, based on the use of high resolution mass spectrometry, will lead in the near future to the detection of a wider range of oxidized PAHs in abiotic matrices (i.e. water, sediment) and hopefully in biota, and bringing along new research challenges Anna Marqueño acknowledges a pre-doctoral fellowship BES-2015-074842. This work has been carried out under project CGL2014-52144-P Peer Reviewed 2018-01-26T07:42:14Z 2018-01-26T07:42:14Z 2017 2018-01-26T07:42:14Z capítulo de libro http://purl.org/coar/resource_type/c_3248 isbn: 978-1-68108-428-2 isbn: 978-1-68108-427-5 Petrogenic Polycyclic Aromatic Hydrocarbons in the Aquatic Environment : Analysis, Synthesis, Toxicity and Environmental Impact 5: 111-134 (2017) http://hdl.handle.net/10261/159680 https://doi.org/10.2174/97816810842751170101 Sí none Bentham Science Publishers |
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Oxidized PAHs Metabolism Endocrine alteration Analysis Oxidized PAHs Metabolism Endocrine alteration Analysis |
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Oxidized PAHs Metabolism Endocrine alteration Analysis Oxidized PAHs Metabolism Endocrine alteration Analysis Fernandes, Denise Marqueño, Anna Porte Visa, Cinta Solé, Montserrat PAH Metabolites in Fish and Invertebrates: Analysis and Endocrine Disruptive Potential |
description |
24 pages, 2 figures, 1 table |
format |
capítulo de libro |
topic_facet |
Oxidized PAHs Metabolism Endocrine alteration Analysis |
author |
Fernandes, Denise Marqueño, Anna Porte Visa, Cinta Solé, Montserrat |
author_facet |
Fernandes, Denise Marqueño, Anna Porte Visa, Cinta Solé, Montserrat |
author_sort |
Fernandes, Denise |
title |
PAH Metabolites in Fish and Invertebrates: Analysis and Endocrine Disruptive Potential |
title_short |
PAH Metabolites in Fish and Invertebrates: Analysis and Endocrine Disruptive Potential |
title_full |
PAH Metabolites in Fish and Invertebrates: Analysis and Endocrine Disruptive Potential |
title_fullStr |
PAH Metabolites in Fish and Invertebrates: Analysis and Endocrine Disruptive Potential |
title_full_unstemmed |
PAH Metabolites in Fish and Invertebrates: Analysis and Endocrine Disruptive Potential |
title_sort |
pah metabolites in fish and invertebrates: analysis and endocrine disruptive potential |
publisher |
Bentham Science Publishers |
publishDate |
2017 |
url |
http://hdl.handle.net/10261/159680 |
work_keys_str_mv |
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1777666664433713152 |