Multicolor FISH  using tándem probes to detect Chromosome alterations in humans cells and populations exposed to genotoxic agents

Eastmond, David A.; Rupa, Doppalapudi S.; Schuler, Maik J.; Murg, Michelle N.; Peña de Torres, Eduardo de la

Multicolor FISH using tándem probes to detect Chromosome alterations in humans cells and populations exposed to genotoxic agents

12 páginas, 2 figuras y 2 tablas estadísticas

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Bibliographic Details
Main Authors:	Eastmond, David A., Rupa, Doppalapudi S., Schuler, Maik J., Murg, Michelle N., Peña de Torres, Eduardo de la
Format:	capítulo de libro biblioteca
Language:	English
Published:	Sociedad Española de Mutagénesis Ambiental 1999
Subjects:	Fluorescence in situ hybridization (FISH), Chromosome alterations, Genotoxic agents,
Online Access:	http://hdl.handle.net/10261/99650
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id	dig-ica-es-10261-99650
record_format	koha
spelling	dig-ica-es-10261-996502016-02-17T20:49:24Z Multicolor FISH using tándem probes to detect Chromosome alterations in humans cells and populations exposed to genotoxic agents Eastmond, David A. Rupa, Doppalapudi S. Schuler, Maik J. Murg, Michelle N. Peña de Torres, Eduardo de la Fluorescence in situ hybridization (FISH) Chromosome alterations Genotoxic agents 12 páginas, 2 figuras y 2 tablas estadísticas Fluorescence in situ hybridization (FISH) with chromosome- or region-specific DNA probes is being increasingly used in cytogenetic studies to detect aneuploidy in interphase human cells. This technique utilizes chemically modified DNA sequences (probes) which hybridize to distinct regions, often blocks of repetitive DNA, located on specific chromosomes. Hybridization with these probes in situ results in the staining of a compact chromosomal región which can be easily detected on metaphase chromosomes or within interphase nuclei. The number of chromosomes within a given cell is then determined by counting the number of hybridized regions. Where conventional cytogenetics is limited to actively proliferating cells or those which could be stimulated to divide in vitro such as peripheral blood lymphocytes, FISH studies with centromeric probes can be conducted on interphase cells, significantly increasing the types of cells and tissues available for analysis. Peer reviewed 2014-07-09T09:54:30Z 2014-07-09T09:54:30Z 1999 capítulo de libro http://purl.org/coar/resource_type/c_3248 Evaluación Mutagénica y Genotóxica: 249-260 (1999) http://hdl.handle.net/10261/99650 en Sí open Sociedad Española de Mutagénesis Ambiental
institution	ICA ES
collection	DSpace
country	España
countrycode	ES
component	Bibliográfico
access	En linea
databasecode	dig-ica-es
tag	biblioteca
region	Europa del Sur
libraryname	Biblioteca del ICA España
language	English
topic	Fluorescence in situ hybridization (FISH) Chromosome alterations Genotoxic agents Fluorescence in situ hybridization (FISH) Chromosome alterations Genotoxic agents
spellingShingle	Fluorescence in situ hybridization (FISH) Chromosome alterations Genotoxic agents Fluorescence in situ hybridization (FISH) Chromosome alterations Genotoxic agents Eastmond, David A. Rupa, Doppalapudi S. Schuler, Maik J. Murg, Michelle N. Peña de Torres, Eduardo de la Multicolor FISH using tándem probes to detect Chromosome alterations in humans cells and populations exposed to genotoxic agents
description	12 páginas, 2 figuras y 2 tablas estadísticas
format	capítulo de libro
topic_facet	Fluorescence in situ hybridization (FISH) Chromosome alterations Genotoxic agents
author	Eastmond, David A. Rupa, Doppalapudi S. Schuler, Maik J. Murg, Michelle N. Peña de Torres, Eduardo de la
author_facet	Eastmond, David A. Rupa, Doppalapudi S. Schuler, Maik J. Murg, Michelle N. Peña de Torres, Eduardo de la
author_sort	Eastmond, David A.
title	Multicolor FISH using tándem probes to detect Chromosome alterations in humans cells and populations exposed to genotoxic agents
title_short	Multicolor FISH using tándem probes to detect Chromosome alterations in humans cells and populations exposed to genotoxic agents
title_full	Multicolor FISH using tándem probes to detect Chromosome alterations in humans cells and populations exposed to genotoxic agents
title_fullStr	Multicolor FISH using tándem probes to detect Chromosome alterations in humans cells and populations exposed to genotoxic agents
title_full_unstemmed	Multicolor FISH using tándem probes to detect Chromosome alterations in humans cells and populations exposed to genotoxic agents
title_sort	multicolor fish using tándem probes to detect chromosome alterations in humans cells and populations exposed to genotoxic agents
publisher	Sociedad Española de Mutagénesis Ambiental
publishDate	1999
url	http://hdl.handle.net/10261/99650
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Multicolor FISH using tándem probes to detect Chromosome alterations in humans cells and populations exposed to genotoxic agents

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