Great ape genetic diversity and population history
Trabajo presentado en la 4th Meeting of the Spanish Society of the Evolutionary Biology (SESBE 2013) celebrada en Barcelona del 27 al 29 de noviembre de 2013.
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2013-11
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dig-ibe-es-10261-1534072018-10-03T07:36:47Z Great ape genetic diversity and population history Prado-Martinez, Javier Great Ape Genome Diversity Marqués-Bonet, Tomàs Trabajo presentado en la 4th Meeting of the Spanish Society of the Evolutionary Biology (SESBE 2013) celebrada en Barcelona del 27 al 29 de noviembre de 2013. Despite African great apes and orangutans are human’s closest evolutionary relatives, the assessment of their genetic diversity has been systematically delayed in comparison to similar studies in our species. To overcome this limitation, we sequenced to high coverage a total of 79 great ape individuals representing all species and seven subspe- cies across the African continent and South East Asia. We discover ~86.5 million single nucleotide polymorphisms and report a three-fold range in nucleotide diversity among different ape populations. We find extensive inbreeding in almost all wild populations with Eastern gorillas being the most extreme population. Our analysis provides support for genetically distinct populations within each species, signals of gene flow, and the split of common chimpanzees into two distinct groups: Nigeria-Cameroon/Western and Central/Eastern populations. Using these data, we develop a framework to understand the recent evolutionary history of hominidae. This resource provides the first catalog of great-ape genome diversity to assist in better understanding our species and more effectively managing wild and captive great ape populations. No 2017-07-24T07:26:54Z 2017-07-24T07:26:54Z 2013-11 comunicación de congreso http://purl.org/coar/resource_type/c_5794 4th Meeting of the Spanish Society for Evolutionary Biology (2013) http://hdl.handle.net/10261/153407 en Sí none |
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Trabajo presentado en la 4th Meeting of the Spanish Society of the Evolutionary Biology (SESBE 2013) celebrada en Barcelona del 27 al 29 de noviembre de 2013. |
format |
comunicación de congreso |
author |
Prado-Martinez, Javier Great Ape Genome Diversity Marqués-Bonet, Tomàs |
spellingShingle |
Prado-Martinez, Javier Great Ape Genome Diversity Marqués-Bonet, Tomàs Great ape genetic diversity and population history |
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Prado-Martinez, Javier Great Ape Genome Diversity Marqués-Bonet, Tomàs |
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Prado-Martinez, Javier |
title |
Great ape genetic diversity and population history |
title_short |
Great ape genetic diversity and population history |
title_full |
Great ape genetic diversity and population history |
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Great ape genetic diversity and population history |
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Great ape genetic diversity and population history |
title_sort |
great ape genetic diversity and population history |
publishDate |
2013-11 |
url |
http://hdl.handle.net/10261/153407 |
work_keys_str_mv |
AT pradomartinezjavier greatapegeneticdiversityandpopulationhistory AT greatapegenomediversity greatapegeneticdiversityandpopulationhistory AT marquesbonettomas greatapegeneticdiversityandpopulationhistory |
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1777668688948756480 |