Effects of Marine Bioactive Compounds on Gut Ecology Based on In Vitro Digestion and Colonic Fermentation Models

Digestion and the absorption of food compounds are necessary steps before nutrients can exert a role in human health. The absorption and utilization of nutrients in the diet is an extremely complex dynamic process. Accurately grasping the digestion and absorption mechanisms of different nutrients or bioactive compounds can provide a better understanding regarding the relationship between health and nutrition. Several in vitro models for simulating human gastrointestinal digestion and colonic fermentation have been established to obtain more accurate data for further understanding of the metabolism of dietary components. Marine media is rich in a wide variety of nutrients that are essential for humans and is gaining increased attention as a research topic. This review summarizes some of the most explored in vitro digestion and colonic fermentation models. It also summarizes the research progress on the digestion and absorption of nutrients and bioactive compounds from marine substrates when subjected to these in vitro models. Additionally, an overview of the changes imparted by the digestion process on these bioactive compounds is provided, in order to support those marine resources that can be utilized for developing new healthy foods.

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Bibliographic Details
Main Authors: Wang, Min, Zhou, Jianjun, Calvo Lerma, Joaquim, Liu, Yixuan, Collado, María Carmen, Barba, Francisco J.
Other Authors: European Commission
Format: artículo biblioteca
Language:English
Published: Multidisciplinary Digital Publishing Institute 2022-08-12
Subjects:In vitro digestion, Colonic fermentation, Marine bioactive compounds, Digestion model,
Online Access:http://hdl.handle.net/10261/278404
http://dx.doi.org/10.13039/501100000780
http://dx.doi.org/10.13039/501100004543
http://dx.doi.org/10.13039/501100011033
http://dx.doi.org/10.13039/501100000811
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spelling dig-iata-es-10261-2784042023-01-26T15:43:37Z Effects of Marine Bioactive Compounds on Gut Ecology Based on In Vitro Digestion and Colonic Fermentation Models Wang, Min Zhou, Jianjun Calvo Lerma, Joaquim Liu, Yixuan Collado, María Carmen Barba, Francisco J. European Commission European Institute of Innovation and Technology China Scholarship Council Ministerio de Ciencia, Innovación y Universidades (España) Agencia Estatal de Investigación (España) In vitro digestion Colonic fermentation Marine bioactive compounds Digestion model Digestion and the absorption of food compounds are necessary steps before nutrients can exert a role in human health. The absorption and utilization of nutrients in the diet is an extremely complex dynamic process. Accurately grasping the digestion and absorption mechanisms of different nutrients or bioactive compounds can provide a better understanding regarding the relationship between health and nutrition. Several in vitro models for simulating human gastrointestinal digestion and colonic fermentation have been established to obtain more accurate data for further understanding of the metabolism of dietary components. Marine media is rich in a wide variety of nutrients that are essential for humans and is gaining increased attention as a research topic. This review summarizes some of the most explored in vitro digestion and colonic fermentation models. It also summarizes the research progress on the digestion and absorption of nutrients and bioactive compounds from marine substrates when subjected to these in vitro models. Additionally, an overview of the changes imparted by the digestion process on these bioactive compounds is provided, in order to support those marine resources that can be utilized for developing new healthy foods. F.J.B. would like to acknowledge the EU Commission for the funds provided by the BBIJU through the H2020 Project AQUABIOPRO-FIT “Aquaculture and agriculture biomass side stream proteins and bioactives for feed, fitness and health promoting nutritional supplements” (Grant Agreement no. 790956). M.C.C. and J.C.-L. would like to acknowledge the support from EIT FOOD (MAMMAL, ref. 212.56). Min Wang and Jianjun Zhou were supported by a PhD fellowship from the China Scholarship Council (CSC) (No. 201908420245 and No. 201908420246, respectively). We acknowledge the Juan de la Cierva Formación post-doctoral contract awarded to Joaquim Calvo-Lerma by the Spanish Ministry of Science and Innovation (FJC2019-041730-I). Peer reviewed 2022-09-04T10:36:10Z 2022-09-04T10:36:10Z 2022-08-12 2022-09-04T10:36:10Z artículo Nutrients 14(16): 3307 (2022) http://hdl.handle.net/10261/278404 10.3390/nu14163307 2072-6643 http://dx.doi.org/10.13039/501100000780 http://dx.doi.org/10.13039/501100004543 http://dx.doi.org/10.13039/501100011033 http://dx.doi.org/10.13039/501100000811 en #PLACEHOLDER_PARENT_METADATA_VALUE# #PLACEHOLDER_PARENT_METADATA_VALUE# info:eu-repo/grantAgreement/EC/H2020/790956 info:eu-repo/grantAgreement/AEI//FJC2019-041730-I Publisher's version https://doi.org/10.3390/nu14163307 Sí open application/pdf Multidisciplinary Digital Publishing Institute
institution IATA ES
collection DSpace
country España
countrycode ES
component Bibliográfico
access En linea
databasecode dig-iata-es
tag biblioteca
region Europa del Sur
libraryname Biblioteca del IATA España
language English
topic In vitro digestion
Colonic fermentation
Marine bioactive compounds
Digestion model
In vitro digestion
Colonic fermentation
Marine bioactive compounds
Digestion model
spellingShingle In vitro digestion
Colonic fermentation
Marine bioactive compounds
Digestion model
In vitro digestion
Colonic fermentation
Marine bioactive compounds
Digestion model
Wang, Min
Zhou, Jianjun
Calvo Lerma, Joaquim
Liu, Yixuan
Collado, María Carmen
Barba, Francisco J.
Effects of Marine Bioactive Compounds on Gut Ecology Based on In Vitro Digestion and Colonic Fermentation Models
description Digestion and the absorption of food compounds are necessary steps before nutrients can exert a role in human health. The absorption and utilization of nutrients in the diet is an extremely complex dynamic process. Accurately grasping the digestion and absorption mechanisms of different nutrients or bioactive compounds can provide a better understanding regarding the relationship between health and nutrition. Several in vitro models for simulating human gastrointestinal digestion and colonic fermentation have been established to obtain more accurate data for further understanding of the metabolism of dietary components. Marine media is rich in a wide variety of nutrients that are essential for humans and is gaining increased attention as a research topic. This review summarizes some of the most explored in vitro digestion and colonic fermentation models. It also summarizes the research progress on the digestion and absorption of nutrients and bioactive compounds from marine substrates when subjected to these in vitro models. Additionally, an overview of the changes imparted by the digestion process on these bioactive compounds is provided, in order to support those marine resources that can be utilized for developing new healthy foods.
author2 European Commission
author_facet European Commission
Wang, Min
Zhou, Jianjun
Calvo Lerma, Joaquim
Liu, Yixuan
Collado, María Carmen
Barba, Francisco J.
format artículo
topic_facet In vitro digestion
Colonic fermentation
Marine bioactive compounds
Digestion model
author Wang, Min
Zhou, Jianjun
Calvo Lerma, Joaquim
Liu, Yixuan
Collado, María Carmen
Barba, Francisco J.
author_sort Wang, Min
title Effects of Marine Bioactive Compounds on Gut Ecology Based on In Vitro Digestion and Colonic Fermentation Models
title_short Effects of Marine Bioactive Compounds on Gut Ecology Based on In Vitro Digestion and Colonic Fermentation Models
title_full Effects of Marine Bioactive Compounds on Gut Ecology Based on In Vitro Digestion and Colonic Fermentation Models
title_fullStr Effects of Marine Bioactive Compounds on Gut Ecology Based on In Vitro Digestion and Colonic Fermentation Models
title_full_unstemmed Effects of Marine Bioactive Compounds on Gut Ecology Based on In Vitro Digestion and Colonic Fermentation Models
title_sort effects of marine bioactive compounds on gut ecology based on in vitro digestion and colonic fermentation models
publisher Multidisciplinary Digital Publishing Institute
publishDate 2022-08-12
url http://hdl.handle.net/10261/278404
http://dx.doi.org/10.13039/501100000780
http://dx.doi.org/10.13039/501100004543
http://dx.doi.org/10.13039/501100011033
http://dx.doi.org/10.13039/501100000811
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