Generation of bioactive peptides during food processing
Large amounts of peptides are naturally generated in foods through the proteolysis phenomena taking place during processing. Such proteolysis is carried out either by endogenous enzymes in ripened foods or by the combined action of endogenous and microbial enzymes when fermented. Food proteins can also be isolated and hydrolysed by peptidases to produce hydrolysates. endo-peptidases act first followed by the successive action of exo-peptidases (mainly, tri- and di-peptidylpeptidases, aminopeptidases and carboxypeptidases). The generated peptides may be further hydrolysed through the gastrointestinal digestion resulting in a pool of peptides with different sequences and lengths, some of them with relevant bioactivity. However, these peptides should be absorbed intact through the intestinal barrier and reach the blood stream to exert their physiological action. This manuscript is reporting the enzymatic routes and strategies followed for the generation of bioactive peptides.
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Format: | artículo biblioteca |
Language: | English |
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Elsevier
2017-06-21
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Subjects: | Bioactive peptides, Proteomics, Proteolysis, Peptides, Enzymes, Peptidases, Exo-peptidases, |
Online Access: | http://hdl.handle.net/10261/166570 http://dx.doi.org/10.13039/501100003329 http://dx.doi.org/10.13039/501100000780 |
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dig-iata-es-10261-1665702019-02-06T07:49:53Z Generation of bioactive peptides during food processing Toldrá Vilardell, Fidel Reig, Milagro Aristoy, María Concepción Mora, Leticia Ministerio de Economía y Competitividad (España) European Commission Bioactive peptides Proteomics Proteolysis Peptides Enzymes Peptidases Exo-peptidases Large amounts of peptides are naturally generated in foods through the proteolysis phenomena taking place during processing. Such proteolysis is carried out either by endogenous enzymes in ripened foods or by the combined action of endogenous and microbial enzymes when fermented. Food proteins can also be isolated and hydrolysed by peptidases to produce hydrolysates. endo-peptidases act first followed by the successive action of exo-peptidases (mainly, tri- and di-peptidylpeptidases, aminopeptidases and carboxypeptidases). The generated peptides may be further hydrolysed through the gastrointestinal digestion resulting in a pool of peptides with different sequences and lengths, some of them with relevant bioactivity. However, these peptides should be absorbed intact through the intestinal barrier and reach the blood stream to exert their physiological action. This manuscript is reporting the enzymatic routes and strategies followed for the generation of bioactive peptides. The research leading to these results received funding from Grant AGL2014-57367-R from the Spanish Ministry of Economy, Industry and Competitivity and FEDER funds and from the European Union 7th Framework Programme (FP7/2007-2013) under Grant Agreement 312090 (BACCHUS). Peer reviewed 2018-06-19T07:19:14Z 2018-06-19T07:19:14Z 2017-06-21 artículo http://purl.org/coar/resource_type/c_6501 Food Chemistry 267: 395-404 (2018) 0308-8146 http://hdl.handle.net/10261/166570 10.1016/j.foodchem.2017.06.119 http://dx.doi.org/10.13039/501100003329 http://dx.doi.org/10.13039/501100000780 en #PLACEHOLDER_PARENT_METADATA_VALUE# #PLACEHOLDER_PARENT_METADATA_VALUE# info:eu-repo/grantAgreement/MINECO/Plan Estatal de Investigación Científica y Técnica y de Innovación 2013-2016/AGL2014-57367-R info:eu-repo/grantAgreement/EC/FP7/312090 Postprint https://doi.org/10.1016/j.foodchem.2017.06.119 Sí open Elsevier |
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Bioactive peptides Proteomics Proteolysis Peptides Enzymes Peptidases Exo-peptidases Bioactive peptides Proteomics Proteolysis Peptides Enzymes Peptidases Exo-peptidases |
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Bioactive peptides Proteomics Proteolysis Peptides Enzymes Peptidases Exo-peptidases Bioactive peptides Proteomics Proteolysis Peptides Enzymes Peptidases Exo-peptidases Toldrá Vilardell, Fidel Reig, Milagro Aristoy, María Concepción Mora, Leticia Generation of bioactive peptides during food processing |
description |
Large amounts of peptides are naturally generated in foods through the proteolysis phenomena taking place during processing. Such proteolysis is carried out either by endogenous enzymes in ripened foods or by the combined action of endogenous and microbial enzymes when fermented. Food proteins can also be isolated and hydrolysed by peptidases to produce hydrolysates. endo-peptidases act first followed by the successive action of exo-peptidases (mainly, tri- and di-peptidylpeptidases, aminopeptidases and carboxypeptidases). The generated peptides may be further hydrolysed through the gastrointestinal digestion resulting in a pool of peptides with different sequences and lengths, some of them with relevant bioactivity. However, these peptides should be absorbed intact through the intestinal barrier and reach the blood stream to exert their physiological action. This manuscript is reporting the enzymatic routes and strategies followed for the generation of bioactive peptides. |
author2 |
Ministerio de Economía y Competitividad (España) |
author_facet |
Ministerio de Economía y Competitividad (España) Toldrá Vilardell, Fidel Reig, Milagro Aristoy, María Concepción Mora, Leticia |
format |
artículo |
topic_facet |
Bioactive peptides Proteomics Proteolysis Peptides Enzymes Peptidases Exo-peptidases |
author |
Toldrá Vilardell, Fidel Reig, Milagro Aristoy, María Concepción Mora, Leticia |
author_sort |
Toldrá Vilardell, Fidel |
title |
Generation of bioactive peptides during food processing |
title_short |
Generation of bioactive peptides during food processing |
title_full |
Generation of bioactive peptides during food processing |
title_fullStr |
Generation of bioactive peptides during food processing |
title_full_unstemmed |
Generation of bioactive peptides during food processing |
title_sort |
generation of bioactive peptides during food processing |
publisher |
Elsevier |
publishDate |
2017-06-21 |
url |
http://hdl.handle.net/10261/166570 http://dx.doi.org/10.13039/501100003329 http://dx.doi.org/10.13039/501100000780 |
work_keys_str_mv |
AT toldravilardellfidel generationofbioactivepeptidesduringfoodprocessing AT reigmilagro generationofbioactivepeptidesduringfoodprocessing AT aristoymariaconcepcion generationofbioactivepeptidesduringfoodprocessing AT moraleticia generationofbioactivepeptidesduringfoodprocessing |
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1777670060744114176 |