Toxicological in vivo and in vitro evaluation of three diet abundant phenols: Tyrosol, ferulic and vanillic acids
Trabajo presentado en el 52nd Congress of the European Societies of Toxicology (EUROTOX 2016), celebrado en Sevilla del 4 al 7 de septiembre de 2016.
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2016-09
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dig-ias-es-10261-1558822018-08-01T10:17:12Z Toxicological in vivo and in vitro evaluation of three diet abundant phenols: Tyrosol, ferulic and vanillic acids Merinas-Amo, T. Merinas-Amo, R. Valenzuela-Gómez, F. Haro Bailón, Antonio de Lozano, María Dolores Mateo-Fernández, M. Fernández-Bedmar, Zahira Alonso Moraga, Ángeles Trabajo presentado en el 52nd Congress of the European Societies of Toxicology (EUROTOX 2016), celebrado en Sevilla del 4 al 7 de septiembre de 2016. Tyrosol, ferulic and vanillic acids are phenolic present in diet (vegetables, fruits, virgin olive oil and derived from degrada- tion of lignin). They have been shown to have healthy activities due to their high variety of physiological functions such as antioxidant activity. The aim of this study was to know their bio- logicalactivitiesindegenerative-relatedprocessesattheindividual and molecular levels. For this purpose, in vivo toxi/antitoxicity, geno/antigenotoxicity and longevity assays were carried out in the Drosophila melanogaster model. Moreover, in vitro assays were performed in HL-60 human leukaemia cell line testing their cyto- toxicity and proapoptotic DNA internucleosomal fragmentation potency. The results showed that phenols were non-toxic for flies. No 2017-09-29T11:26:18Z 2017-09-29T11:26:18Z 2016-09 póster de congreso http://purl.org/coar/resource_type/c_6670 52nd Congress of the European Societies of Toxicology (2016) http://hdl.handle.net/10261/155882 en Sí none |
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English |
| description |
Trabajo presentado en el 52nd Congress of the European Societies of Toxicology (EUROTOX 2016), celebrado en Sevilla del 4 al 7 de septiembre de 2016. |
| format |
póster de congreso |
| author |
Merinas-Amo, T. Merinas-Amo, R. Valenzuela-Gómez, F. Haro Bailón, Antonio de Lozano, María Dolores Mateo-Fernández, M. Fernández-Bedmar, Zahira Alonso Moraga, Ángeles |
| spellingShingle |
Merinas-Amo, T. Merinas-Amo, R. Valenzuela-Gómez, F. Haro Bailón, Antonio de Lozano, María Dolores Mateo-Fernández, M. Fernández-Bedmar, Zahira Alonso Moraga, Ángeles Toxicological in vivo and in vitro evaluation of three diet abundant phenols: Tyrosol, ferulic and vanillic acids |
| author_facet |
Merinas-Amo, T. Merinas-Amo, R. Valenzuela-Gómez, F. Haro Bailón, Antonio de Lozano, María Dolores Mateo-Fernández, M. Fernández-Bedmar, Zahira Alonso Moraga, Ángeles |
| author_sort |
Merinas-Amo, T. |
| title |
Toxicological in vivo and in vitro evaluation of three diet abundant phenols: Tyrosol, ferulic and vanillic acids |
| title_short |
Toxicological in vivo and in vitro evaluation of three diet abundant phenols: Tyrosol, ferulic and vanillic acids |
| title_full |
Toxicological in vivo and in vitro evaluation of three diet abundant phenols: Tyrosol, ferulic and vanillic acids |
| title_fullStr |
Toxicological in vivo and in vitro evaluation of three diet abundant phenols: Tyrosol, ferulic and vanillic acids |
| title_full_unstemmed |
Toxicological in vivo and in vitro evaluation of three diet abundant phenols: Tyrosol, ferulic and vanillic acids |
| title_sort |
toxicological in vivo and in vitro evaluation of three diet abundant phenols: tyrosol, ferulic and vanillic acids |
| publishDate |
2016-09 |
| url |
http://hdl.handle.net/10261/155882 |
| work_keys_str_mv |
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| _version_ |
1777663108666359808 |