Horizontal gene transfer plays a major role in the pathological convergence of Xanthomonas lineages on common bean
Background: Host specialization is a hallmark of numerous plant pathogens including bacteria, fungi, oomycetes and viruses. Yet, the molecular and evolutionary bases of host specificity are poorly understood. In some cases, pathological convergence is observed for individuals belonging to distant phylogenetic clades. This is the case for Xanthomonas strains responsible for common bacterial blight of bean, spread across four genetic lineages. All the strains from these four lineages converged for pathogenicity on common bean, implying possible gene convergences and/or sharing of a common arsenal of genes conferring the ability to infect common bean. Results: To search for genes involved in common bean specificity, we used a combination of whole-genome analyses without a priori, including a genome scan based on k-mer search. Analysis of 72 genomes from a collection of Xanthomonas pathovars unveiled 115 genes bearing DNA sequences specific to strains responsible for common bacterial blight, including 20 genes located on a plasmid. Of these 115 genes, 88 were involved in successive events of horizontal gene transfers among the four genetic lineages, and 44 contained nonsynonymous polymorphisms unique to the causal agents of common bacterial blight. Conclusions: Our study revealed that host specificity of common bacterial blight agents is associated with a combination of horizontal transfers of genes, and highlights the role of plasmids in these horizontal transfers.
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dig-cirad-fr-608001 |
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Francia |
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FR |
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Bibliográfico |
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dig-cirad-fr |
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Europa del Oeste |
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Biblioteca del CIRAD Francia |
language |
eng |
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phylogénie Xanthomonas transfert de gène pathologie végétale Xanthomonas campestris citri séquence nucléotidique génome virus des végétaux haricot commun lignée champignon pathogène génie génétique gène http://aims.fao.org/aos/agrovoc/c_13325 http://aims.fao.org/aos/agrovoc/c_8455 http://aims.fao.org/aos/agrovoc/c_24846 http://aims.fao.org/aos/agrovoc/c_5974 http://aims.fao.org/aos/agrovoc/c_36120 http://aims.fao.org/aos/agrovoc/c_27583 http://aims.fao.org/aos/agrovoc/c_3224 http://aims.fao.org/aos/agrovoc/c_5985 http://aims.fao.org/aos/agrovoc/c_4098 http://aims.fao.org/aos/agrovoc/c_29225 http://aims.fao.org/aos/agrovoc/c_29233 http://aims.fao.org/aos/agrovoc/c_15974 http://aims.fao.org/aos/agrovoc/c_3214 http://aims.fao.org/aos/agrovoc/c_3081 http://aims.fao.org/aos/agrovoc/c_6543 phylogénie Xanthomonas transfert de gène pathologie végétale Xanthomonas campestris citri séquence nucléotidique génome virus des végétaux haricot commun lignée champignon pathogène génie génétique gène http://aims.fao.org/aos/agrovoc/c_13325 http://aims.fao.org/aos/agrovoc/c_8455 http://aims.fao.org/aos/agrovoc/c_24846 http://aims.fao.org/aos/agrovoc/c_5974 http://aims.fao.org/aos/agrovoc/c_36120 http://aims.fao.org/aos/agrovoc/c_27583 http://aims.fao.org/aos/agrovoc/c_3224 http://aims.fao.org/aos/agrovoc/c_5985 http://aims.fao.org/aos/agrovoc/c_4098 http://aims.fao.org/aos/agrovoc/c_29225 http://aims.fao.org/aos/agrovoc/c_29233 http://aims.fao.org/aos/agrovoc/c_15974 http://aims.fao.org/aos/agrovoc/c_3214 http://aims.fao.org/aos/agrovoc/c_3081 http://aims.fao.org/aos/agrovoc/c_6543 |
spellingShingle |
phylogénie Xanthomonas transfert de gène pathologie végétale Xanthomonas campestris citri séquence nucléotidique génome virus des végétaux haricot commun lignée champignon pathogène génie génétique gène http://aims.fao.org/aos/agrovoc/c_13325 http://aims.fao.org/aos/agrovoc/c_8455 http://aims.fao.org/aos/agrovoc/c_24846 http://aims.fao.org/aos/agrovoc/c_5974 http://aims.fao.org/aos/agrovoc/c_36120 http://aims.fao.org/aos/agrovoc/c_27583 http://aims.fao.org/aos/agrovoc/c_3224 http://aims.fao.org/aos/agrovoc/c_5985 http://aims.fao.org/aos/agrovoc/c_4098 http://aims.fao.org/aos/agrovoc/c_29225 http://aims.fao.org/aos/agrovoc/c_29233 http://aims.fao.org/aos/agrovoc/c_15974 http://aims.fao.org/aos/agrovoc/c_3214 http://aims.fao.org/aos/agrovoc/c_3081 http://aims.fao.org/aos/agrovoc/c_6543 phylogénie Xanthomonas transfert de gène pathologie végétale Xanthomonas campestris citri séquence nucléotidique génome virus des végétaux haricot commun lignée champignon pathogène génie génétique gène http://aims.fao.org/aos/agrovoc/c_13325 http://aims.fao.org/aos/agrovoc/c_8455 http://aims.fao.org/aos/agrovoc/c_24846 http://aims.fao.org/aos/agrovoc/c_5974 http://aims.fao.org/aos/agrovoc/c_36120 http://aims.fao.org/aos/agrovoc/c_27583 http://aims.fao.org/aos/agrovoc/c_3224 http://aims.fao.org/aos/agrovoc/c_5985 http://aims.fao.org/aos/agrovoc/c_4098 http://aims.fao.org/aos/agrovoc/c_29225 http://aims.fao.org/aos/agrovoc/c_29233 http://aims.fao.org/aos/agrovoc/c_15974 http://aims.fao.org/aos/agrovoc/c_3214 http://aims.fao.org/aos/agrovoc/c_3081 http://aims.fao.org/aos/agrovoc/c_6543 Chen, Nicolas W.G. Serres-Giardi, Laurana Ruh, Mylène Briand, Martial Bonneau, Sophie Darrasse, Armelle Barbe, Valérie Gagnevin, Lionel Koebnik, Ralf Jacques, Marie Agnès Horizontal gene transfer plays a major role in the pathological convergence of Xanthomonas lineages on common bean |
description |
Background: Host specialization is a hallmark of numerous plant pathogens including bacteria, fungi, oomycetes and viruses. Yet, the molecular and evolutionary bases of host specificity are poorly understood. In some cases, pathological convergence is observed for individuals belonging to distant phylogenetic clades. This is the case for Xanthomonas strains responsible for common bacterial blight of bean, spread across four genetic lineages. All the strains from these four lineages converged for pathogenicity on common bean, implying possible gene convergences and/or sharing of a common arsenal of genes conferring the ability to infect common bean. Results: To search for genes involved in common bean specificity, we used a combination of whole-genome analyses without a priori, including a genome scan based on k-mer search. Analysis of 72 genomes from a collection of Xanthomonas pathovars unveiled 115 genes bearing DNA sequences specific to strains responsible for common bacterial blight, including 20 genes located on a plasmid. Of these 115 genes, 88 were involved in successive events of horizontal gene transfers among the four genetic lineages, and 44 contained nonsynonymous polymorphisms unique to the causal agents of common bacterial blight. Conclusions: Our study revealed that host specificity of common bacterial blight agents is associated with a combination of horizontal transfers of genes, and highlights the role of plasmids in these horizontal transfers. |
format |
article |
topic_facet |
phylogénie Xanthomonas transfert de gène pathologie végétale Xanthomonas campestris citri séquence nucléotidique génome virus des végétaux haricot commun lignée champignon pathogène génie génétique gène http://aims.fao.org/aos/agrovoc/c_13325 http://aims.fao.org/aos/agrovoc/c_8455 http://aims.fao.org/aos/agrovoc/c_24846 http://aims.fao.org/aos/agrovoc/c_5974 http://aims.fao.org/aos/agrovoc/c_36120 http://aims.fao.org/aos/agrovoc/c_27583 http://aims.fao.org/aos/agrovoc/c_3224 http://aims.fao.org/aos/agrovoc/c_5985 http://aims.fao.org/aos/agrovoc/c_4098 http://aims.fao.org/aos/agrovoc/c_29225 http://aims.fao.org/aos/agrovoc/c_29233 http://aims.fao.org/aos/agrovoc/c_15974 http://aims.fao.org/aos/agrovoc/c_3214 http://aims.fao.org/aos/agrovoc/c_3081 http://aims.fao.org/aos/agrovoc/c_6543 |
author |
Chen, Nicolas W.G. Serres-Giardi, Laurana Ruh, Mylène Briand, Martial Bonneau, Sophie Darrasse, Armelle Barbe, Valérie Gagnevin, Lionel Koebnik, Ralf Jacques, Marie Agnès |
author_facet |
Chen, Nicolas W.G. Serres-Giardi, Laurana Ruh, Mylène Briand, Martial Bonneau, Sophie Darrasse, Armelle Barbe, Valérie Gagnevin, Lionel Koebnik, Ralf Jacques, Marie Agnès |
author_sort |
Chen, Nicolas W.G. |
title |
Horizontal gene transfer plays a major role in the pathological convergence of Xanthomonas lineages on common bean |
title_short |
Horizontal gene transfer plays a major role in the pathological convergence of Xanthomonas lineages on common bean |
title_full |
Horizontal gene transfer plays a major role in the pathological convergence of Xanthomonas lineages on common bean |
title_fullStr |
Horizontal gene transfer plays a major role in the pathological convergence of Xanthomonas lineages on common bean |
title_full_unstemmed |
Horizontal gene transfer plays a major role in the pathological convergence of Xanthomonas lineages on common bean |
title_sort |
horizontal gene transfer plays a major role in the pathological convergence of xanthomonas lineages on common bean |
url |
http://agritrop.cirad.fr/608001/ http://agritrop.cirad.fr/608001/1/s12864-018-4975-4.pdf |
work_keys_str_mv |
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1792500732642983936 |
spelling |
dig-cirad-fr-6080012024-01-29T06:23:36Z http://agritrop.cirad.fr/608001/ http://agritrop.cirad.fr/608001/ Horizontal gene transfer plays a major role in the pathological convergence of Xanthomonas lineages on common bean. Chen Nicolas W.G., Serres-Giardi Laurana, Ruh Mylène, Briand Martial, Bonneau Sophie, Darrasse Armelle, Barbe Valérie, Gagnevin Lionel, Koebnik Ralf, Jacques Marie Agnès. 2018. BMC Genomics, 19:606, 20 p.https://doi.org/10.1186/s12864-018-4975-4 <https://doi.org/10.1186/s12864-018-4975-4> Horizontal gene transfer plays a major role in the pathological convergence of Xanthomonas lineages on common bean Chen, Nicolas W.G. Serres-Giardi, Laurana Ruh, Mylène Briand, Martial Bonneau, Sophie Darrasse, Armelle Barbe, Valérie Gagnevin, Lionel Koebnik, Ralf Jacques, Marie Agnès eng 2018 BMC Genomics phylogénie Xanthomonas transfert de gène pathologie végétale Xanthomonas campestris citri séquence nucléotidique génome virus des végétaux haricot commun lignée champignon pathogène génie génétique gène http://aims.fao.org/aos/agrovoc/c_13325 http://aims.fao.org/aos/agrovoc/c_8455 http://aims.fao.org/aos/agrovoc/c_24846 http://aims.fao.org/aos/agrovoc/c_5974 http://aims.fao.org/aos/agrovoc/c_36120 http://aims.fao.org/aos/agrovoc/c_27583 http://aims.fao.org/aos/agrovoc/c_3224 http://aims.fao.org/aos/agrovoc/c_5985 http://aims.fao.org/aos/agrovoc/c_4098 http://aims.fao.org/aos/agrovoc/c_29225 http://aims.fao.org/aos/agrovoc/c_29233 http://aims.fao.org/aos/agrovoc/c_15974 http://aims.fao.org/aos/agrovoc/c_3214 France La Réunion http://aims.fao.org/aos/agrovoc/c_3081 http://aims.fao.org/aos/agrovoc/c_6543 Background: Host specialization is a hallmark of numerous plant pathogens including bacteria, fungi, oomycetes and viruses. Yet, the molecular and evolutionary bases of host specificity are poorly understood. In some cases, pathological convergence is observed for individuals belonging to distant phylogenetic clades. This is the case for Xanthomonas strains responsible for common bacterial blight of bean, spread across four genetic lineages. All the strains from these four lineages converged for pathogenicity on common bean, implying possible gene convergences and/or sharing of a common arsenal of genes conferring the ability to infect common bean. Results: To search for genes involved in common bean specificity, we used a combination of whole-genome analyses without a priori, including a genome scan based on k-mer search. Analysis of 72 genomes from a collection of Xanthomonas pathovars unveiled 115 genes bearing DNA sequences specific to strains responsible for common bacterial blight, including 20 genes located on a plasmid. Of these 115 genes, 88 were involved in successive events of horizontal gene transfers among the four genetic lineages, and 44 contained nonsynonymous polymorphisms unique to the causal agents of common bacterial blight. Conclusions: Our study revealed that host specificity of common bacterial blight agents is associated with a combination of horizontal transfers of genes, and highlights the role of plasmids in these horizontal transfers. article info:eu-repo/semantics/article Journal Article info:eu-repo/semantics/publishedVersion http://agritrop.cirad.fr/608001/1/s12864-018-4975-4.pdf text cc_by info:eu-repo/semantics/openAccess https://creativecommons.org/licenses/by/4.0/ https://doi.org/10.1186/s12864-018-4975-4 10.1186/s12864-018-4975-4 info:eu-repo/semantics/altIdentifier/doi/10.1186/s12864-018-4975-4 info:eu-repo/semantics/altIdentifier/purl/https://doi.org/10.1186/s12864-018-4975-4 info:eu-repo/semantics/dataset/purl/https://figshare.com/articles/journal_contribution/Additional_file_1_of_Horizontal_gene_transfer_plays_a_major_role_in_the_pathological_convergence_of_Xanthomonas_lineages_on_common_bean/6963314 info:eu-repo/grantAgreement///ANR-10-GENM-0013//(FRA) Etude comparative des génomes et des transcriptomes de Xanthomonas phytopathogènes/XANTHOMIX info:eu-repo/grantAgreement///ANR-10-INBS-0009//(FRA) Organisation et montée en puissance d'une Infrastructure Nationale de Génomique/France-Génomique |