Clinical findings associated with Nterminal pro-B-type natriuretic peptide measurement in dogs and cats attending first opinion veterinary practices

Background: Clinical findings associated with N-terminal pro-B-type natriuretic peptide (NT-proBNP) measurement in dogs and cats in primary practice, and their relevance to published measurement indications, have not been described. Methods: Using electronic health record data collected by the Small Animal Veterinary Surveillance Network, appointments in which NT-proBNP was measured were identified using keyword-based text filtering. For these appointments, clinical findings were manually identified from each patient's clinical narrative (CN) and their frequencies described. Results: CNs of 3510 appointments (357 dogs and 257 cats) from 99practices were evaluated. The most frequently recorded clinical findings in dogs were: heart murmur (n = 147, 41.2% (95% confidence interval (CI) = 36.1%–46.3%), coughing (n = 83, 23.2% (95% CI = 18.8%–27.6%)) and panting (n = 58, 16.2% (95% CI = 12.4%–20.0%)) and in cats: heart murmur (n = 143, 55.6% (95% CI = 49.5%–61.7%)), suspected thromboembolism (n = 88, 34.2% (95% CI = 28.4%–40.0%)) and weight loss (n = 53, 20.6% (95% CI = 15.7%–25.5%)). Dyspnoea and tachypnoea were infrequently reported in dogs (n = 29, 8.1% (95% CI = 5.3%–10.9%) and n = 21, 5.9% (95% CI = 3.5%–8.3%), respectively) and cats (n = 26, 10.1% (95% CI = 6.4%–13.8%) and n = 36, 14.0% (95% CI = 9.8%–18.2%), respectively). Conclusion: Clinical findings referable to cardiac disease were recorded contemporaneously with NT-proBNP measurement and suggested both published and other indications (coughing (in dogs and cats), and serial measurements and thromboembolism (in cats)) for testing.

Bibliographic Details

Main Authors:	O'Shaughnessy, Sarah, Crawford, India, Arsevska, Elena, Singleton, David, Hughes, David, Noble, Peter-John, Hezzell, Mélanie
Format:	article biblioteca
Language:	eng
Subjects:	chien, chat, surveillance épidémiologique, race de chat, santé animale, mesure (activité), diagnostic, cardiomyopathie, dyspnée, cardiopathie, http://aims.fao.org/aos/agrovoc/c_2352, http://aims.fao.org/aos/agrovoc/c_1390, http://aims.fao.org/aos/agrovoc/c_16411, http://aims.fao.org/aos/agrovoc/c_6eab3ebd, http://aims.fao.org/aos/agrovoc/c_431, http://aims.fao.org/aos/agrovoc/c_4668, http://aims.fao.org/aos/agrovoc/c_2238, http://aims.fao.org/aos/agrovoc/c_33961, http://aims.fao.org/aos/agrovoc/c_10501, http://aims.fao.org/aos/agrovoc/c_3517,
Online Access:	http://agritrop.cirad.fr/606391/ http://agritrop.cirad.fr/606391/1/ID606391.pdf
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