Experimental demonstration of the impact of hard and soft selection regimes on polymorphism maintenance in spatially heterogeneous environments
Predicting and managing contemporary adaption requires a proper understanding of the determinants of genetic variation. Spatial heterogeneity of the environment may stably maintain polymorphism when habitat contribution to the next generation can be considered independent of the degree of adaptation of local populations within habitats (i.e., under soft selection). In contrast, when habitats contribute proportionally to the mean fitness of the populations they host (hard selection), polymorphism is not expected to be maintained by selection. Although mathematically established decades ago, this prediction had never been demonstrated experimentally. Here, we provide an experimental test in which polymorphic populations of Escherichia coli growing in heterogeneous habitats were exposed to hard and soft selection regimes. As predicted by theory, polymorphism was preserved longer under soft selection. Complementary tests established that soft selection slowed fixation processes and could even protect polymorphism in the long term by providing a systematic advantage to rare genotypes.
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Subjects: | U30 - Méthodes de recherche, 000 - Autres thèmes, Bacteria, Escherichia coli, évolution, variation génétique, polymorphisme génétique, génétique des populations, http://aims.fao.org/aos/agrovoc/c_765, http://aims.fao.org/aos/agrovoc/c_33700, http://aims.fao.org/aos/agrovoc/c_2745, http://aims.fao.org/aos/agrovoc/c_15975, http://aims.fao.org/aos/agrovoc/c_24031, http://aims.fao.org/aos/agrovoc/c_34326, |
Online Access: | http://agritrop.cirad.fr/592227/ http://agritrop.cirad.fr/592227/7/Gallet_et_al-2018-Evolution.pdf |
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dig-cirad-fr-5922272024-01-29T01:54:02Z http://agritrop.cirad.fr/592227/ http://agritrop.cirad.fr/592227/ Experimental demonstration of the impact of hard and soft selection regimes on polymorphism maintenance in spatially heterogeneous environments. Gallet Romain, Froissart Rémi, Ravigné Virginie. 2018. Evolution, 72 (8) : 1677-1688.https://doi.org/10.1111/evo.13513 <https://doi.org/10.1111/evo.13513> Experimental demonstration of the impact of hard and soft selection regimes on polymorphism maintenance in spatially heterogeneous environments Gallet, Romain Froissart, Rémi Ravigné, Virginie eng 2018 Evolution U30 - Méthodes de recherche 000 - Autres thèmes Bacteria Escherichia coli évolution variation génétique polymorphisme génétique génétique des populations http://aims.fao.org/aos/agrovoc/c_765 http://aims.fao.org/aos/agrovoc/c_33700 http://aims.fao.org/aos/agrovoc/c_2745 http://aims.fao.org/aos/agrovoc/c_15975 http://aims.fao.org/aos/agrovoc/c_24031 http://aims.fao.org/aos/agrovoc/c_34326 Predicting and managing contemporary adaption requires a proper understanding of the determinants of genetic variation. Spatial heterogeneity of the environment may stably maintain polymorphism when habitat contribution to the next generation can be considered independent of the degree of adaptation of local populations within habitats (i.e., under soft selection). In contrast, when habitats contribute proportionally to the mean fitness of the populations they host (hard selection), polymorphism is not expected to be maintained by selection. Although mathematically established decades ago, this prediction had never been demonstrated experimentally. Here, we provide an experimental test in which polymorphic populations of Escherichia coli growing in heterogeneous habitats were exposed to hard and soft selection regimes. As predicted by theory, polymorphism was preserved longer under soft selection. Complementary tests established that soft selection slowed fixation processes and could even protect polymorphism in the long term by providing a systematic advantage to rare genotypes. article info:eu-repo/semantics/article Journal Article info:eu-repo/semantics/publishedVersion http://agritrop.cirad.fr/592227/7/Gallet_et_al-2018-Evolution.pdf text Cirad license info:eu-repo/semantics/restrictedAccess https://agritrop.cirad.fr/mention_legale.html https://doi.org/10.1111/evo.13513 10.1111/evo.13513 info:eu-repo/semantics/altIdentifier/doi/10.1111/evo.13513 info:eu-repo/semantics/altIdentifier/purl/https://doi.org/10.1111/evo.13513 info:eu-repo/semantics/dataset/purl/https://doi.org/10.5061/dryad.261553q info:eu-repo/grantAgreement/EC///// |
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U30 - Méthodes de recherche 000 - Autres thèmes Bacteria Escherichia coli évolution variation génétique polymorphisme génétique génétique des populations http://aims.fao.org/aos/agrovoc/c_765 http://aims.fao.org/aos/agrovoc/c_33700 http://aims.fao.org/aos/agrovoc/c_2745 http://aims.fao.org/aos/agrovoc/c_15975 http://aims.fao.org/aos/agrovoc/c_24031 http://aims.fao.org/aos/agrovoc/c_34326 U30 - Méthodes de recherche 000 - Autres thèmes Bacteria Escherichia coli évolution variation génétique polymorphisme génétique génétique des populations http://aims.fao.org/aos/agrovoc/c_765 http://aims.fao.org/aos/agrovoc/c_33700 http://aims.fao.org/aos/agrovoc/c_2745 http://aims.fao.org/aos/agrovoc/c_15975 http://aims.fao.org/aos/agrovoc/c_24031 http://aims.fao.org/aos/agrovoc/c_34326 |
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U30 - Méthodes de recherche 000 - Autres thèmes Bacteria Escherichia coli évolution variation génétique polymorphisme génétique génétique des populations http://aims.fao.org/aos/agrovoc/c_765 http://aims.fao.org/aos/agrovoc/c_33700 http://aims.fao.org/aos/agrovoc/c_2745 http://aims.fao.org/aos/agrovoc/c_15975 http://aims.fao.org/aos/agrovoc/c_24031 http://aims.fao.org/aos/agrovoc/c_34326 U30 - Méthodes de recherche 000 - Autres thèmes Bacteria Escherichia coli évolution variation génétique polymorphisme génétique génétique des populations http://aims.fao.org/aos/agrovoc/c_765 http://aims.fao.org/aos/agrovoc/c_33700 http://aims.fao.org/aos/agrovoc/c_2745 http://aims.fao.org/aos/agrovoc/c_15975 http://aims.fao.org/aos/agrovoc/c_24031 http://aims.fao.org/aos/agrovoc/c_34326 Gallet, Romain Froissart, Rémi Ravigné, Virginie Experimental demonstration of the impact of hard and soft selection regimes on polymorphism maintenance in spatially heterogeneous environments |
description |
Predicting and managing contemporary adaption requires a proper understanding of the determinants of genetic variation. Spatial heterogeneity of the environment may stably maintain polymorphism when habitat contribution to the next generation can be considered independent of the degree of adaptation of local populations within habitats (i.e., under soft selection). In contrast, when habitats contribute proportionally to the mean fitness of the populations they host (hard selection), polymorphism is not expected to be maintained by selection. Although mathematically established decades ago, this prediction had never been demonstrated experimentally. Here, we provide an experimental test in which polymorphic populations of Escherichia coli growing in heterogeneous habitats were exposed to hard and soft selection regimes. As predicted by theory, polymorphism was preserved longer under soft selection. Complementary tests established that soft selection slowed fixation processes and could even protect polymorphism in the long term by providing a systematic advantage to rare genotypes. |
format |
article |
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U30 - Méthodes de recherche 000 - Autres thèmes Bacteria Escherichia coli évolution variation génétique polymorphisme génétique génétique des populations http://aims.fao.org/aos/agrovoc/c_765 http://aims.fao.org/aos/agrovoc/c_33700 http://aims.fao.org/aos/agrovoc/c_2745 http://aims.fao.org/aos/agrovoc/c_15975 http://aims.fao.org/aos/agrovoc/c_24031 http://aims.fao.org/aos/agrovoc/c_34326 |
author |
Gallet, Romain Froissart, Rémi Ravigné, Virginie |
author_facet |
Gallet, Romain Froissart, Rémi Ravigné, Virginie |
author_sort |
Gallet, Romain |
title |
Experimental demonstration of the impact of hard and soft selection regimes on polymorphism maintenance in spatially heterogeneous environments |
title_short |
Experimental demonstration of the impact of hard and soft selection regimes on polymorphism maintenance in spatially heterogeneous environments |
title_full |
Experimental demonstration of the impact of hard and soft selection regimes on polymorphism maintenance in spatially heterogeneous environments |
title_fullStr |
Experimental demonstration of the impact of hard and soft selection regimes on polymorphism maintenance in spatially heterogeneous environments |
title_full_unstemmed |
Experimental demonstration of the impact of hard and soft selection regimes on polymorphism maintenance in spatially heterogeneous environments |
title_sort |
experimental demonstration of the impact of hard and soft selection regimes on polymorphism maintenance in spatially heterogeneous environments |
url |
http://agritrop.cirad.fr/592227/ http://agritrop.cirad.fr/592227/7/Gallet_et_al-2018-Evolution.pdf |
work_keys_str_mv |
AT galletromain experimentaldemonstrationoftheimpactofhardandsoftselectionregimesonpolymorphismmaintenanceinspatiallyheterogeneousenvironments AT froissartremi experimentaldemonstrationoftheimpactofhardandsoftselectionregimesonpolymorphismmaintenanceinspatiallyheterogeneousenvironments AT ravignevirginie experimentaldemonstrationoftheimpactofhardandsoftselectionregimesonpolymorphismmaintenanceinspatiallyheterogeneousenvironments |
_version_ |
1792499718283067392 |