Unexpected field observations and transmission dynamics of contagious caprine pleuropneumonia in a sand gazelle herd
Contagious caprine pleuropneumonia (CCPP), caused by Mycoplasma capricolum subsp. capripneumoniae, has long been considered a goat-specific disease. Since 2007 there has been growing evidence that this disease can affect wild ungulates either kept in captivity or in the wild. In 2013, a large collection of sand gazelles (Gazella marica) held in the United Arab Emirates suffered heavy losses due to a CCPP epizootic confirmed by PCR and isolation. Animals displayed typical lesions, with unilateral pneumonia and profuse pleurisy. An initial antibiotic treatment consisting of tylosin administered in drinking water did not improve the animals' condition and vaccination failed to stop the spread to contiguous pens. A treatment with tetracycline mixed in feed pellets finally succeeded to stop the evolution of the disease. A subsequent vaccine trial, performed on naïve animals, showed that only a reference CCPP vaccine produced according to OIE standards induced a sero-conversion by CCPP competition ELISA, while the commercially available vaccines did not. A SEIRD compartment transmission model was developed to better understand the dynamics of the disease. The parameters were initially set as per expert opinion and then adjusted to fit the observed mortality data. The basic reproductive number R0 was estimated to be between 2.3–2.7, while the final mortality rate reached up to 70% in some pens. Transmission of infectious droplets from an external source, through a distance of at least the 50 m separating the pens from the perimeter fence, remains the most plausible explanation for the contamination of this stock of gazelles.
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dig-cirad-fr-5888092023-12-01T17:01:13Z http://agritrop.cirad.fr/588809/ http://agritrop.cirad.fr/588809/ Unexpected field observations and transmission dynamics of contagious caprine pleuropneumonia in a sand gazelle herd. Lignereux Louis, Chaber Anne-Lise, Saegerman Claude, Manso-Silvan Lucia, Peyraud Armelle, Apolloni Andrea, Thiaucourt François. 2018. Preventive Veterinary Medicine, 157 : 70-77.https://doi.org/10.1016/j.prevetmed.2018.06.002 <https://doi.org/10.1016/j.prevetmed.2018.06.002> Unexpected field observations and transmission dynamics of contagious caprine pleuropneumonia in a sand gazelle herd Lignereux, Louis Chaber, Anne-Lise Saegerman, Claude Manso-Silvan, Lucia Peyraud, Armelle Apolloni, Andrea Thiaucourt, François eng 2018 Preventive Veterinary Medicine L73 - Maladies des animaux P01 - Conservation de la nature et ressources foncières Émirats arabes unis http://aims.fao.org/aos/agrovoc/c_8067 Contagious caprine pleuropneumonia (CCPP), caused by Mycoplasma capricolum subsp. capripneumoniae, has long been considered a goat-specific disease. Since 2007 there has been growing evidence that this disease can affect wild ungulates either kept in captivity or in the wild. In 2013, a large collection of sand gazelles (Gazella marica) held in the United Arab Emirates suffered heavy losses due to a CCPP epizootic confirmed by PCR and isolation. Animals displayed typical lesions, with unilateral pneumonia and profuse pleurisy. An initial antibiotic treatment consisting of tylosin administered in drinking water did not improve the animals' condition and vaccination failed to stop the spread to contiguous pens. A treatment with tetracycline mixed in feed pellets finally succeeded to stop the evolution of the disease. A subsequent vaccine trial, performed on naïve animals, showed that only a reference CCPP vaccine produced according to OIE standards induced a sero-conversion by CCPP competition ELISA, while the commercially available vaccines did not. A SEIRD compartment transmission model was developed to better understand the dynamics of the disease. The parameters were initially set as per expert opinion and then adjusted to fit the observed mortality data. The basic reproductive number R0 was estimated to be between 2.3–2.7, while the final mortality rate reached up to 70% in some pens. Transmission of infectious droplets from an external source, through a distance of at least the 50 m separating the pens from the perimeter fence, remains the most plausible explanation for the contamination of this stock of gazelles. article info:eu-repo/semantics/article Journal Article info:eu-repo/semantics/publishedVersion http://agritrop.cirad.fr/588809/7/1-s2.0-S0167587718300837-main.pdf text Cirad license info:eu-repo/semantics/restrictedAccess https://agritrop.cirad.fr/mention_legale.html https://doi.org/10.1016/j.prevetmed.2018.06.002 10.1016/j.prevetmed.2018.06.002 info:eu-repo/semantics/altIdentifier/doi/10.1016/j.prevetmed.2018.06.002 info:eu-repo/semantics/altIdentifier/purl/https://doi.org/10.1016/j.prevetmed.2018.06.002 |
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L73 - Maladies des animaux P01 - Conservation de la nature et ressources foncières http://aims.fao.org/aos/agrovoc/c_8067 L73 - Maladies des animaux P01 - Conservation de la nature et ressources foncières http://aims.fao.org/aos/agrovoc/c_8067 |
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L73 - Maladies des animaux P01 - Conservation de la nature et ressources foncières http://aims.fao.org/aos/agrovoc/c_8067 L73 - Maladies des animaux P01 - Conservation de la nature et ressources foncières http://aims.fao.org/aos/agrovoc/c_8067 Lignereux, Louis Chaber, Anne-Lise Saegerman, Claude Manso-Silvan, Lucia Peyraud, Armelle Apolloni, Andrea Thiaucourt, François Unexpected field observations and transmission dynamics of contagious caprine pleuropneumonia in a sand gazelle herd |
description |
Contagious caprine pleuropneumonia (CCPP), caused by Mycoplasma capricolum subsp. capripneumoniae, has long been considered a goat-specific disease. Since 2007 there has been growing evidence that this disease can affect wild ungulates either kept in captivity or in the wild. In 2013, a large collection of sand gazelles (Gazella marica) held in the United Arab Emirates suffered heavy losses due to a CCPP epizootic confirmed by PCR and isolation. Animals displayed typical lesions, with unilateral pneumonia and profuse pleurisy. An initial antibiotic treatment consisting of tylosin administered in drinking water did not improve the animals' condition and vaccination failed to stop the spread to contiguous pens. A treatment with tetracycline mixed in feed pellets finally succeeded to stop the evolution of the disease. A subsequent vaccine trial, performed on naïve animals, showed that only a reference CCPP vaccine produced according to OIE standards induced a sero-conversion by CCPP competition ELISA, while the commercially available vaccines did not. A SEIRD compartment transmission model was developed to better understand the dynamics of the disease. The parameters were initially set as per expert opinion and then adjusted to fit the observed mortality data. The basic reproductive number R0 was estimated to be between 2.3–2.7, while the final mortality rate reached up to 70% in some pens. Transmission of infectious droplets from an external source, through a distance of at least the 50 m separating the pens from the perimeter fence, remains the most plausible explanation for the contamination of this stock of gazelles. |
format |
article |
topic_facet |
L73 - Maladies des animaux P01 - Conservation de la nature et ressources foncières http://aims.fao.org/aos/agrovoc/c_8067 |
author |
Lignereux, Louis Chaber, Anne-Lise Saegerman, Claude Manso-Silvan, Lucia Peyraud, Armelle Apolloni, Andrea Thiaucourt, François |
author_facet |
Lignereux, Louis Chaber, Anne-Lise Saegerman, Claude Manso-Silvan, Lucia Peyraud, Armelle Apolloni, Andrea Thiaucourt, François |
author_sort |
Lignereux, Louis |
title |
Unexpected field observations and transmission dynamics of contagious caprine pleuropneumonia in a sand gazelle herd |
title_short |
Unexpected field observations and transmission dynamics of contagious caprine pleuropneumonia in a sand gazelle herd |
title_full |
Unexpected field observations and transmission dynamics of contagious caprine pleuropneumonia in a sand gazelle herd |
title_fullStr |
Unexpected field observations and transmission dynamics of contagious caprine pleuropneumonia in a sand gazelle herd |
title_full_unstemmed |
Unexpected field observations and transmission dynamics of contagious caprine pleuropneumonia in a sand gazelle herd |
title_sort |
unexpected field observations and transmission dynamics of contagious caprine pleuropneumonia in a sand gazelle herd |
url |
http://agritrop.cirad.fr/588809/ http://agritrop.cirad.fr/588809/7/1-s2.0-S0167587718300837-main.pdf |
work_keys_str_mv |
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1787232471159406592 |