Rabies Postexposure Prophylaxis (PEP) concompletion after dog bites: Estimating the unseen to meet the needs of the underserved
Post exposure prophylaxis prevents human rabies and is accessible in Cambodia principally in Phnom Penh, the capital. Timely, affordable access to post-exposure prophylaxis is a challenge for the mainly rural population. We aimed to identify districts independently associated with post-exposure prophylaxis (PEP) noncompletion to position frontline vaccination centers. We analyzed the 2009–2013 database at the rabies prevention center of the Institut Pasteur du Cambodge, Phnom Penh. Logistic regressions identified non-geographic determinants of PEP noncompletion and districts after adjustment for these determinants. The influence of distance by road was estimated using a boosted regression trees model. A district noncompletion population attributable fraction (Rabies Index) was computed and mapped. A cartographic analysis based on the statistic developed by Getis and Ord identified clusters of high-Rabies Index districts. Factors independently associated with noncompletion were patients' district of residence, male gender, age 15–49, initial visit during rice harvest, the dog's status (culled or disappeared) as well as a prescribed PEP protocol requiring more than three PEP sessions (four and five). Four clusters of high-Rabies Index (RI) districts were identified using this analytical strategy applicable to many vaccination or other health services. Positioning frontline PEP centers in these districts will significantly widen access to timely and adequate PEP.
Main Authors: | , , , , , , , , , , , , , |
---|---|
Format: | article biblioteca |
Language: | eng |
Subjects: | S50 - Santé humaine, L73 - Maladies des animaux, U10 - Informatique, mathématiques et statistiques, rage, prophylaxie des maladies, vaccin, épidémiologie, cartographie, analyse du risque, http://aims.fao.org/aos/agrovoc/c_6416, http://aims.fao.org/aos/agrovoc/c_13610, http://aims.fao.org/aos/agrovoc/c_8130, http://aims.fao.org/aos/agrovoc/c_2615, http://aims.fao.org/aos/agrovoc/c_1344, http://aims.fao.org/aos/agrovoc/c_37936, http://aims.fao.org/aos/agrovoc/c_4073, |
Online Access: | http://agritrop.cirad.fr/585257/ http://agritrop.cirad.fr/585257/7/585257.pdf |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
id |
dig-cirad-fr-585257 |
---|---|
record_format |
koha |
spelling |
dig-cirad-fr-5852572024-01-29T00:29:06Z http://agritrop.cirad.fr/585257/ http://agritrop.cirad.fr/585257/ Rabies Postexposure Prophylaxis (PEP) concompletion after dog bites: Estimating the unseen to meet the needs of the underserved. Tarantola Arnaud, Blanchi Sophie, Cappelle Julien, Ly Sowath, Chan Malen, In Sotheary, Peng Yiksing, Hing Chanthy, Taing Chun Navy, Ly Sovann, Bourhy Hervé, Buchy Philippe, Dussart Philippe, Mary Jean-Yves. 2018. American Journal of Epidemiology, 187 (2) : 306-315.https://doi.org/10.1093/aje/kwx234 <https://doi.org/10.1093/aje/kwx234> Rabies Postexposure Prophylaxis (PEP) concompletion after dog bites: Estimating the unseen to meet the needs of the underserved Tarantola, Arnaud Blanchi, Sophie Cappelle, Julien Ly, Sowath Chan, Malen In, Sotheary Peng, Yiksing Hing, Chanthy Taing, Chun Navy Ly, Sovann Bourhy, Hervé Buchy, Philippe Dussart, Philippe Mary, Jean-Yves eng 2018 American Journal of Epidemiology S50 - Santé humaine L73 - Maladies des animaux U10 - Informatique, mathématiques et statistiques rage prophylaxie des maladies vaccin épidémiologie cartographie analyse du risque http://aims.fao.org/aos/agrovoc/c_6416 http://aims.fao.org/aos/agrovoc/c_13610 http://aims.fao.org/aos/agrovoc/c_8130 http://aims.fao.org/aos/agrovoc/c_2615 http://aims.fao.org/aos/agrovoc/c_1344 http://aims.fao.org/aos/agrovoc/c_37936 Cambodge http://aims.fao.org/aos/agrovoc/c_4073 Post exposure prophylaxis prevents human rabies and is accessible in Cambodia principally in Phnom Penh, the capital. Timely, affordable access to post-exposure prophylaxis is a challenge for the mainly rural population. We aimed to identify districts independently associated with post-exposure prophylaxis (PEP) noncompletion to position frontline vaccination centers. We analyzed the 2009–2013 database at the rabies prevention center of the Institut Pasteur du Cambodge, Phnom Penh. Logistic regressions identified non-geographic determinants of PEP noncompletion and districts after adjustment for these determinants. The influence of distance by road was estimated using a boosted regression trees model. A district noncompletion population attributable fraction (Rabies Index) was computed and mapped. A cartographic analysis based on the statistic developed by Getis and Ord identified clusters of high-Rabies Index districts. Factors independently associated with noncompletion were patients' district of residence, male gender, age 15–49, initial visit during rice harvest, the dog's status (culled or disappeared) as well as a prescribed PEP protocol requiring more than three PEP sessions (four and five). Four clusters of high-Rabies Index (RI) districts were identified using this analytical strategy applicable to many vaccination or other health services. Positioning frontline PEP centers in these districts will significantly widen access to timely and adequate PEP. article info:eu-repo/semantics/article Journal Article info:eu-repo/semantics/publishedVersion http://agritrop.cirad.fr/585257/7/585257.pdf text Cirad license info:eu-repo/semantics/restrictedAccess https://agritrop.cirad.fr/mention_legale.html https://doi.org/10.1093/aje/kwx234 10.1093/aje/kwx234 info:eu-repo/semantics/altIdentifier/doi/10.1093/aje/kwx234 info:eu-repo/semantics/altIdentifier/purl/https://doi.org/10.1093/aje/kwx234 |
institution |
CIRAD FR |
collection |
DSpace |
country |
Francia |
countrycode |
FR |
component |
Bibliográfico |
access |
En linea |
databasecode |
dig-cirad-fr |
tag |
biblioteca |
region |
Europa del Oeste |
libraryname |
Biblioteca del CIRAD Francia |
language |
eng |
topic |
S50 - Santé humaine L73 - Maladies des animaux U10 - Informatique, mathématiques et statistiques rage prophylaxie des maladies vaccin épidémiologie cartographie analyse du risque http://aims.fao.org/aos/agrovoc/c_6416 http://aims.fao.org/aos/agrovoc/c_13610 http://aims.fao.org/aos/agrovoc/c_8130 http://aims.fao.org/aos/agrovoc/c_2615 http://aims.fao.org/aos/agrovoc/c_1344 http://aims.fao.org/aos/agrovoc/c_37936 http://aims.fao.org/aos/agrovoc/c_4073 S50 - Santé humaine L73 - Maladies des animaux U10 - Informatique, mathématiques et statistiques rage prophylaxie des maladies vaccin épidémiologie cartographie analyse du risque http://aims.fao.org/aos/agrovoc/c_6416 http://aims.fao.org/aos/agrovoc/c_13610 http://aims.fao.org/aos/agrovoc/c_8130 http://aims.fao.org/aos/agrovoc/c_2615 http://aims.fao.org/aos/agrovoc/c_1344 http://aims.fao.org/aos/agrovoc/c_37936 http://aims.fao.org/aos/agrovoc/c_4073 |
spellingShingle |
S50 - Santé humaine L73 - Maladies des animaux U10 - Informatique, mathématiques et statistiques rage prophylaxie des maladies vaccin épidémiologie cartographie analyse du risque http://aims.fao.org/aos/agrovoc/c_6416 http://aims.fao.org/aos/agrovoc/c_13610 http://aims.fao.org/aos/agrovoc/c_8130 http://aims.fao.org/aos/agrovoc/c_2615 http://aims.fao.org/aos/agrovoc/c_1344 http://aims.fao.org/aos/agrovoc/c_37936 http://aims.fao.org/aos/agrovoc/c_4073 S50 - Santé humaine L73 - Maladies des animaux U10 - Informatique, mathématiques et statistiques rage prophylaxie des maladies vaccin épidémiologie cartographie analyse du risque http://aims.fao.org/aos/agrovoc/c_6416 http://aims.fao.org/aos/agrovoc/c_13610 http://aims.fao.org/aos/agrovoc/c_8130 http://aims.fao.org/aos/agrovoc/c_2615 http://aims.fao.org/aos/agrovoc/c_1344 http://aims.fao.org/aos/agrovoc/c_37936 http://aims.fao.org/aos/agrovoc/c_4073 Tarantola, Arnaud Blanchi, Sophie Cappelle, Julien Ly, Sowath Chan, Malen In, Sotheary Peng, Yiksing Hing, Chanthy Taing, Chun Navy Ly, Sovann Bourhy, Hervé Buchy, Philippe Dussart, Philippe Mary, Jean-Yves Rabies Postexposure Prophylaxis (PEP) concompletion after dog bites: Estimating the unseen to meet the needs of the underserved |
description |
Post exposure prophylaxis prevents human rabies and is accessible in Cambodia principally in Phnom Penh, the capital. Timely, affordable access to post-exposure prophylaxis is a challenge for the mainly rural population. We aimed to identify districts independently associated with post-exposure prophylaxis (PEP) noncompletion to position frontline vaccination centers. We analyzed the 2009–2013 database at the rabies prevention center of the Institut Pasteur du Cambodge, Phnom Penh. Logistic regressions identified non-geographic determinants of PEP noncompletion and districts after adjustment for these determinants. The influence of distance by road was estimated using a boosted regression trees model. A district noncompletion population attributable fraction (Rabies Index) was computed and mapped. A cartographic analysis based on the statistic developed by Getis and Ord identified clusters of high-Rabies Index districts. Factors independently associated with noncompletion were patients' district of residence, male gender, age 15–49, initial visit during rice harvest, the dog's status (culled or disappeared) as well as a prescribed PEP protocol requiring more than three PEP sessions (four and five). Four clusters of high-Rabies Index (RI) districts were identified using this analytical strategy applicable to many vaccination or other health services. Positioning frontline PEP centers in these districts will significantly widen access to timely and adequate PEP. |
format |
article |
topic_facet |
S50 - Santé humaine L73 - Maladies des animaux U10 - Informatique, mathématiques et statistiques rage prophylaxie des maladies vaccin épidémiologie cartographie analyse du risque http://aims.fao.org/aos/agrovoc/c_6416 http://aims.fao.org/aos/agrovoc/c_13610 http://aims.fao.org/aos/agrovoc/c_8130 http://aims.fao.org/aos/agrovoc/c_2615 http://aims.fao.org/aos/agrovoc/c_1344 http://aims.fao.org/aos/agrovoc/c_37936 http://aims.fao.org/aos/agrovoc/c_4073 |
author |
Tarantola, Arnaud Blanchi, Sophie Cappelle, Julien Ly, Sowath Chan, Malen In, Sotheary Peng, Yiksing Hing, Chanthy Taing, Chun Navy Ly, Sovann Bourhy, Hervé Buchy, Philippe Dussart, Philippe Mary, Jean-Yves |
author_facet |
Tarantola, Arnaud Blanchi, Sophie Cappelle, Julien Ly, Sowath Chan, Malen In, Sotheary Peng, Yiksing Hing, Chanthy Taing, Chun Navy Ly, Sovann Bourhy, Hervé Buchy, Philippe Dussart, Philippe Mary, Jean-Yves |
author_sort |
Tarantola, Arnaud |
title |
Rabies Postexposure Prophylaxis (PEP) concompletion after dog bites: Estimating the unseen to meet the needs of the underserved |
title_short |
Rabies Postexposure Prophylaxis (PEP) concompletion after dog bites: Estimating the unseen to meet the needs of the underserved |
title_full |
Rabies Postexposure Prophylaxis (PEP) concompletion after dog bites: Estimating the unseen to meet the needs of the underserved |
title_fullStr |
Rabies Postexposure Prophylaxis (PEP) concompletion after dog bites: Estimating the unseen to meet the needs of the underserved |
title_full_unstemmed |
Rabies Postexposure Prophylaxis (PEP) concompletion after dog bites: Estimating the unseen to meet the needs of the underserved |
title_sort |
rabies postexposure prophylaxis (pep) concompletion after dog bites: estimating the unseen to meet the needs of the underserved |
url |
http://agritrop.cirad.fr/585257/ http://agritrop.cirad.fr/585257/7/585257.pdf |
work_keys_str_mv |
AT tarantolaarnaud rabiespostexposureprophylaxispepconcompletionafterdogbitesestimatingtheunseentomeettheneedsoftheunderserved AT blanchisophie rabiespostexposureprophylaxispepconcompletionafterdogbitesestimatingtheunseentomeettheneedsoftheunderserved AT cappellejulien rabiespostexposureprophylaxispepconcompletionafterdogbitesestimatingtheunseentomeettheneedsoftheunderserved AT lysowath rabiespostexposureprophylaxispepconcompletionafterdogbitesestimatingtheunseentomeettheneedsoftheunderserved AT chanmalen rabiespostexposureprophylaxispepconcompletionafterdogbitesestimatingtheunseentomeettheneedsoftheunderserved AT insotheary rabiespostexposureprophylaxispepconcompletionafterdogbitesestimatingtheunseentomeettheneedsoftheunderserved AT pengyiksing rabiespostexposureprophylaxispepconcompletionafterdogbitesestimatingtheunseentomeettheneedsoftheunderserved AT hingchanthy rabiespostexposureprophylaxispepconcompletionafterdogbitesestimatingtheunseentomeettheneedsoftheunderserved AT taingchunnavy rabiespostexposureprophylaxispepconcompletionafterdogbitesestimatingtheunseentomeettheneedsoftheunderserved AT lysovann rabiespostexposureprophylaxispepconcompletionafterdogbitesestimatingtheunseentomeettheneedsoftheunderserved AT bourhyherve rabiespostexposureprophylaxispepconcompletionafterdogbitesestimatingtheunseentomeettheneedsoftheunderserved AT buchyphilippe rabiespostexposureprophylaxispepconcompletionafterdogbitesestimatingtheunseentomeettheneedsoftheunderserved AT dussartphilippe rabiespostexposureprophylaxispepconcompletionafterdogbitesestimatingtheunseentomeettheneedsoftheunderserved AT maryjeanyves rabiespostexposureprophylaxispepconcompletionafterdogbitesestimatingtheunseentomeettheneedsoftheunderserved |
_version_ |
1792499332229890048 |