Drivers of Rift Valley fever epidemics in Madagascar
Rift Valley fever (RVF) is a vector-borne viral disease widespread in Africa. The primary cycle involves mosquitoes and wild and domestic ruminant hosts. Humans are usually contaminated after contact with infected ruminants. As many environmental, agricultural, epidemiological, and anthropogenic factors are implicated in RVF spread, the multidisciplinary One Health approach was needed to identify the drivers of RVF epidemics in Madagascar. We examined the environmental patterns associated with these epidemics, comparing human and ruminant serological data with environmental and cattle-trade data. In contrast to East Africa, environmental drivers did not trigger the epidemics: They only modulated local Rift Valley fever virus (RVFV) transmission in ruminants. Instead, RVFV was introduced through ruminant trade and subsequent movement of cattle between trade hubs caused its long-distance spread within the country. Contact with cattle brought in from infected districts was associated with higher infection risk in slaughterhouse workers. The finding that anthropogenic rather than environmental factors are the main drivers of RVF infection in humans can be used to design better prevention and early detection in the case of RVF resurgence in the region.
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L73 - Maladies des animaux L72 - Organismes nuisibles des animaux 000 - Autres thèmes Virus de la fièvre de la vallée du Rift vecteur de maladie zoonose transmission des maladies analyse du risque épidémiologie genre humain bétail bovin ruminant facteur de risque facteur du milieu marketing Enquête pathologique sérum sanguin surveillance épidémiologique contrôle de maladies fièvre de la Vallée du Rift http://aims.fao.org/aos/agrovoc/c_16463 http://aims.fao.org/aos/agrovoc/c_8164 http://aims.fao.org/aos/agrovoc/c_8530 http://aims.fao.org/aos/agrovoc/c_2329 http://aims.fao.org/aos/agrovoc/c_37936 http://aims.fao.org/aos/agrovoc/c_2615 http://aims.fao.org/aos/agrovoc/c_4586 http://aims.fao.org/aos/agrovoc/c_4397 http://aims.fao.org/aos/agrovoc/c_1391 http://aims.fao.org/aos/agrovoc/c_6695 http://aims.fao.org/aos/agrovoc/c_32668 http://aims.fao.org/aos/agrovoc/c_2594 http://aims.fao.org/aos/agrovoc/c_4620 http://aims.fao.org/aos/agrovoc/c_28665 http://aims.fao.org/aos/agrovoc/c_9323 http://aims.fao.org/aos/agrovoc/c_16411 http://aims.fao.org/aos/agrovoc/c_2327 http://aims.fao.org/aos/agrovoc/c_b08d44fd http://aims.fao.org/aos/agrovoc/c_4510 L73 - Maladies des animaux L72 - Organismes nuisibles des animaux 000 - Autres thèmes Virus de la fièvre de la vallée du Rift vecteur de maladie zoonose transmission des maladies analyse du risque épidémiologie genre humain bétail bovin ruminant facteur de risque facteur du milieu marketing Enquête pathologique sérum sanguin surveillance épidémiologique contrôle de maladies fièvre de la Vallée du Rift http://aims.fao.org/aos/agrovoc/c_16463 http://aims.fao.org/aos/agrovoc/c_8164 http://aims.fao.org/aos/agrovoc/c_8530 http://aims.fao.org/aos/agrovoc/c_2329 http://aims.fao.org/aos/agrovoc/c_37936 http://aims.fao.org/aos/agrovoc/c_2615 http://aims.fao.org/aos/agrovoc/c_4586 http://aims.fao.org/aos/agrovoc/c_4397 http://aims.fao.org/aos/agrovoc/c_1391 http://aims.fao.org/aos/agrovoc/c_6695 http://aims.fao.org/aos/agrovoc/c_32668 http://aims.fao.org/aos/agrovoc/c_2594 http://aims.fao.org/aos/agrovoc/c_4620 http://aims.fao.org/aos/agrovoc/c_28665 http://aims.fao.org/aos/agrovoc/c_9323 http://aims.fao.org/aos/agrovoc/c_16411 http://aims.fao.org/aos/agrovoc/c_2327 http://aims.fao.org/aos/agrovoc/c_b08d44fd http://aims.fao.org/aos/agrovoc/c_4510 |
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L73 - Maladies des animaux L72 - Organismes nuisibles des animaux 000 - Autres thèmes Virus de la fièvre de la vallée du Rift vecteur de maladie zoonose transmission des maladies analyse du risque épidémiologie genre humain bétail bovin ruminant facteur de risque facteur du milieu marketing Enquête pathologique sérum sanguin surveillance épidémiologique contrôle de maladies fièvre de la Vallée du Rift http://aims.fao.org/aos/agrovoc/c_16463 http://aims.fao.org/aos/agrovoc/c_8164 http://aims.fao.org/aos/agrovoc/c_8530 http://aims.fao.org/aos/agrovoc/c_2329 http://aims.fao.org/aos/agrovoc/c_37936 http://aims.fao.org/aos/agrovoc/c_2615 http://aims.fao.org/aos/agrovoc/c_4586 http://aims.fao.org/aos/agrovoc/c_4397 http://aims.fao.org/aos/agrovoc/c_1391 http://aims.fao.org/aos/agrovoc/c_6695 http://aims.fao.org/aos/agrovoc/c_32668 http://aims.fao.org/aos/agrovoc/c_2594 http://aims.fao.org/aos/agrovoc/c_4620 http://aims.fao.org/aos/agrovoc/c_28665 http://aims.fao.org/aos/agrovoc/c_9323 http://aims.fao.org/aos/agrovoc/c_16411 http://aims.fao.org/aos/agrovoc/c_2327 http://aims.fao.org/aos/agrovoc/c_b08d44fd http://aims.fao.org/aos/agrovoc/c_4510 L73 - Maladies des animaux L72 - Organismes nuisibles des animaux 000 - Autres thèmes Virus de la fièvre de la vallée du Rift vecteur de maladie zoonose transmission des maladies analyse du risque épidémiologie genre humain bétail bovin ruminant facteur de risque facteur du milieu marketing Enquête pathologique sérum sanguin surveillance épidémiologique contrôle de maladies fièvre de la Vallée du Rift http://aims.fao.org/aos/agrovoc/c_16463 http://aims.fao.org/aos/agrovoc/c_8164 http://aims.fao.org/aos/agrovoc/c_8530 http://aims.fao.org/aos/agrovoc/c_2329 http://aims.fao.org/aos/agrovoc/c_37936 http://aims.fao.org/aos/agrovoc/c_2615 http://aims.fao.org/aos/agrovoc/c_4586 http://aims.fao.org/aos/agrovoc/c_4397 http://aims.fao.org/aos/agrovoc/c_1391 http://aims.fao.org/aos/agrovoc/c_6695 http://aims.fao.org/aos/agrovoc/c_32668 http://aims.fao.org/aos/agrovoc/c_2594 http://aims.fao.org/aos/agrovoc/c_4620 http://aims.fao.org/aos/agrovoc/c_28665 http://aims.fao.org/aos/agrovoc/c_9323 http://aims.fao.org/aos/agrovoc/c_16411 http://aims.fao.org/aos/agrovoc/c_2327 http://aims.fao.org/aos/agrovoc/c_b08d44fd http://aims.fao.org/aos/agrovoc/c_4510 Lancelot, Renaud Beral, Marina Rakotoharinome, Vincent Michel Andriamandimby, Soa Fy Héraud, Jean Michel Coste, Caroline Apolloni, Andrea Squarzoni, Cécile De La Rocque, Stéphane Formenty, Pierre Bouyer, Jérémy Wint, Willy Cardinale, Eric Drivers of Rift Valley fever epidemics in Madagascar |
description |
Rift Valley fever (RVF) is a vector-borne viral disease widespread in Africa. The primary cycle involves mosquitoes and wild and domestic ruminant hosts. Humans are usually contaminated after contact with infected ruminants. As many environmental, agricultural, epidemiological, and anthropogenic factors are implicated in RVF spread, the multidisciplinary One Health approach was needed to identify the drivers of RVF epidemics in Madagascar. We examined the environmental patterns associated with these epidemics, comparing human and ruminant serological data with environmental and cattle-trade data. In contrast to East Africa, environmental drivers did not trigger the epidemics: They only modulated local Rift Valley fever virus (RVFV) transmission in ruminants. Instead, RVFV was introduced through ruminant trade and subsequent movement of cattle between trade hubs caused its long-distance spread within the country. Contact with cattle brought in from infected districts was associated with higher infection risk in slaughterhouse workers. The finding that anthropogenic rather than environmental factors are the main drivers of RVF infection in humans can be used to design better prevention and early detection in the case of RVF resurgence in the region. |
format |
article |
topic_facet |
L73 - Maladies des animaux L72 - Organismes nuisibles des animaux 000 - Autres thèmes Virus de la fièvre de la vallée du Rift vecteur de maladie zoonose transmission des maladies analyse du risque épidémiologie genre humain bétail bovin ruminant facteur de risque facteur du milieu marketing Enquête pathologique sérum sanguin surveillance épidémiologique contrôle de maladies fièvre de la Vallée du Rift http://aims.fao.org/aos/agrovoc/c_16463 http://aims.fao.org/aos/agrovoc/c_8164 http://aims.fao.org/aos/agrovoc/c_8530 http://aims.fao.org/aos/agrovoc/c_2329 http://aims.fao.org/aos/agrovoc/c_37936 http://aims.fao.org/aos/agrovoc/c_2615 http://aims.fao.org/aos/agrovoc/c_4586 http://aims.fao.org/aos/agrovoc/c_4397 http://aims.fao.org/aos/agrovoc/c_1391 http://aims.fao.org/aos/agrovoc/c_6695 http://aims.fao.org/aos/agrovoc/c_32668 http://aims.fao.org/aos/agrovoc/c_2594 http://aims.fao.org/aos/agrovoc/c_4620 http://aims.fao.org/aos/agrovoc/c_28665 http://aims.fao.org/aos/agrovoc/c_9323 http://aims.fao.org/aos/agrovoc/c_16411 http://aims.fao.org/aos/agrovoc/c_2327 http://aims.fao.org/aos/agrovoc/c_b08d44fd http://aims.fao.org/aos/agrovoc/c_4510 |
author |
Lancelot, Renaud Beral, Marina Rakotoharinome, Vincent Michel Andriamandimby, Soa Fy Héraud, Jean Michel Coste, Caroline Apolloni, Andrea Squarzoni, Cécile De La Rocque, Stéphane Formenty, Pierre Bouyer, Jérémy Wint, Willy Cardinale, Eric |
author_facet |
Lancelot, Renaud Beral, Marina Rakotoharinome, Vincent Michel Andriamandimby, Soa Fy Héraud, Jean Michel Coste, Caroline Apolloni, Andrea Squarzoni, Cécile De La Rocque, Stéphane Formenty, Pierre Bouyer, Jérémy Wint, Willy Cardinale, Eric |
author_sort |
Lancelot, Renaud |
title |
Drivers of Rift Valley fever epidemics in Madagascar |
title_short |
Drivers of Rift Valley fever epidemics in Madagascar |
title_full |
Drivers of Rift Valley fever epidemics in Madagascar |
title_fullStr |
Drivers of Rift Valley fever epidemics in Madagascar |
title_full_unstemmed |
Drivers of Rift Valley fever epidemics in Madagascar |
title_sort |
drivers of rift valley fever epidemics in madagascar |
url |
http://agritrop.cirad.fr/583139/ http://agritrop.cirad.fr/583139/7/PNAS-2017-Lancelot-938-43.pdf |
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dig-cirad-fr-5831392024-01-28T23:58:50Z http://agritrop.cirad.fr/583139/ http://agritrop.cirad.fr/583139/ Drivers of Rift Valley fever epidemics in Madagascar. Lancelot Renaud, Beral Marina, Rakotoharinome Vincent Michel, Andriamandimby Soa Fy, Héraud Jean Michel, Coste Caroline, Apolloni Andrea, Squarzoni Cécile, De La Rocque Stéphane, Formenty Pierre, Bouyer Jérémy, Wint Willy, Cardinale Eric. 2017. Proceedings of the National Academy of Sciences of the United States of America, 114 (5) : 938-943.https://doi.org/10.1073/pnas.1607948114 <https://doi.org/10.1073/pnas.1607948114> Drivers of Rift Valley fever epidemics in Madagascar Lancelot, Renaud Beral, Marina Rakotoharinome, Vincent Michel Andriamandimby, Soa Fy Héraud, Jean Michel Coste, Caroline Apolloni, Andrea Squarzoni, Cécile De La Rocque, Stéphane Formenty, Pierre Bouyer, Jérémy Wint, Willy Cardinale, Eric eng 2017 Proceedings of the National Academy of Sciences of the United States of America L73 - Maladies des animaux L72 - Organismes nuisibles des animaux 000 - Autres thèmes Virus de la fièvre de la vallée du Rift vecteur de maladie zoonose transmission des maladies analyse du risque épidémiologie genre humain bétail bovin ruminant facteur de risque facteur du milieu marketing Enquête pathologique sérum sanguin surveillance épidémiologique contrôle de maladies fièvre de la Vallée du Rift http://aims.fao.org/aos/agrovoc/c_16463 http://aims.fao.org/aos/agrovoc/c_8164 http://aims.fao.org/aos/agrovoc/c_8530 http://aims.fao.org/aos/agrovoc/c_2329 http://aims.fao.org/aos/agrovoc/c_37936 http://aims.fao.org/aos/agrovoc/c_2615 http://aims.fao.org/aos/agrovoc/c_4586 http://aims.fao.org/aos/agrovoc/c_4397 http://aims.fao.org/aos/agrovoc/c_1391 http://aims.fao.org/aos/agrovoc/c_6695 http://aims.fao.org/aos/agrovoc/c_32668 http://aims.fao.org/aos/agrovoc/c_2594 http://aims.fao.org/aos/agrovoc/c_4620 http://aims.fao.org/aos/agrovoc/c_28665 http://aims.fao.org/aos/agrovoc/c_9323 http://aims.fao.org/aos/agrovoc/c_16411 http://aims.fao.org/aos/agrovoc/c_2327 http://aims.fao.org/aos/agrovoc/c_b08d44fd Madagascar http://aims.fao.org/aos/agrovoc/c_4510 Rift Valley fever (RVF) is a vector-borne viral disease widespread in Africa. The primary cycle involves mosquitoes and wild and domestic ruminant hosts. Humans are usually contaminated after contact with infected ruminants. As many environmental, agricultural, epidemiological, and anthropogenic factors are implicated in RVF spread, the multidisciplinary One Health approach was needed to identify the drivers of RVF epidemics in Madagascar. We examined the environmental patterns associated with these epidemics, comparing human and ruminant serological data with environmental and cattle-trade data. In contrast to East Africa, environmental drivers did not trigger the epidemics: They only modulated local Rift Valley fever virus (RVFV) transmission in ruminants. Instead, RVFV was introduced through ruminant trade and subsequent movement of cattle between trade hubs caused its long-distance spread within the country. Contact with cattle brought in from infected districts was associated with higher infection risk in slaughterhouse workers. The finding that anthropogenic rather than environmental factors are the main drivers of RVF infection in humans can be used to design better prevention and early detection in the case of RVF resurgence in the region. article info:eu-repo/semantics/article Journal Article info:eu-repo/semantics/publishedVersion http://agritrop.cirad.fr/583139/7/PNAS-2017-Lancelot-938-43.pdf text Cirad license info:eu-repo/semantics/openAccess https://agritrop.cirad.fr/mention_legale.html https://doi.org/10.1073/pnas.1607948114 10.1073/pnas.1607948114 info:eu-repo/semantics/altIdentifier/doi/10.1073/pnas.1607948114 info:eu-repo/semantics/altIdentifier/purl/https://doi.org/10.1073/pnas.1607948114 info:eu-repo/semantics/dataset/purl/https://figshare.com/s/73ffd8ff3d3011c8e741 info:eu-repo/semantics/dataset/purl/https://figshare.com/s/7a1c14c8f0a5ccb7e7b8 info:eu-repo/semantics/dataset/purl/https://figshare.com/s/f09650b3309a1a944f15 info:eu-repo/semantics/dataset/purl/https://figshare.com/s/84924c2fbc37f03f4ab1 info:eu-repo/semantics/dataset/purl/https://figshare.com/s/a0a8ec4be4d78dbd53ac info:eu-repo/grantAgreement/EC/FP7/613996//(EU) Emerging viral vector borne diseases/VMERGE |