Proteinuria during dengue fever in children
Objectives: This study aimed to investigate proteinuria occurring during dengue disease in children and assess if measurement of this parameter can help physicians in the clinical management of patients. Methods: Proteinuria was assessed by dipstick and quantified by urine protein:creatinine ratio (UPCR) in samples from patients hospitalized with a confirmed dengue infection and in healthy controls. Results: The dipstick tested positive in 42.9% of the patients presenting at hospital with dengue versus 20.0% in healthy controls. UPCR increased during the critical phase of the disease; peaking one week after fever onset then decreasing as the patients recovered. Patients with warnings signs or severe dengue were more likely to present with proteinuria detected by UPCR at the time of hospital admission compared to patients without warning signs. The sensitivity of this marker, however, was limited as only 16.1% of the patients with warning signs had proteinuria. Conclusions: Urine dipstick and UPCR do not seem to be very valuable for the triage of the patients at the time of the initial consultation but the observation of a decrease of the UPCR during the course of the illness appears to indicate an evolution towards recovery.
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Subjects: | 000 - Autres thèmes, L73 - Maladies des animaux, U30 - Méthodes de recherche, flavivirus, enfant, protéinurie, créatinine, urine, électrophorèse, diagnostic, infection, http://aims.fao.org/aos/agrovoc/c_2963, http://aims.fao.org/aos/agrovoc/c_1547, http://aims.fao.org/aos/agrovoc/c_13628, http://aims.fao.org/aos/agrovoc/c_1953, http://aims.fao.org/aos/agrovoc/c_8103, http://aims.fao.org/aos/agrovoc/c_2523, http://aims.fao.org/aos/agrovoc/c_2238, http://aims.fao.org/aos/agrovoc/c_3852, http://aims.fao.org/aos/agrovoc/c_36735, http://aims.fao.org/aos/agrovoc/c_4073, |
Online Access: | http://agritrop.cirad.fr/583100/ http://agritrop.cirad.fr/583100/1/1-s2.0-S1201971216316678-main.pdf |
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dig-cirad-fr-5831002024-01-28T23:58:33Z http://agritrop.cirad.fr/583100/ http://agritrop.cirad.fr/583100/ Proteinuria during dengue fever in children. Andries Anne-Claire, Duong Veasna, Cappelle Julien, Ong Sivuth, Kerleguer Alexandra, Ly Sowath, Tarantola Arnaud, Horwood Paul, Sakuntabhai Anavaj, Dussart Philippe, Buchy Philippe. 2017. International Journal of Infectious Diseases, 55 : 38-44.https://doi.org/10.1016/j.ijid.2016.12.022 <https://doi.org/10.1016/j.ijid.2016.12.022> Proteinuria during dengue fever in children Andries, Anne-Claire Duong, Veasna Cappelle, Julien Ong, Sivuth Kerleguer, Alexandra Ly, Sowath Tarantola, Arnaud Horwood, Paul Sakuntabhai, Anavaj Dussart, Philippe Buchy, Philippe eng 2017 International Journal of Infectious Diseases 000 - Autres thèmes L73 - Maladies des animaux U30 - Méthodes de recherche flavivirus enfant protéinurie créatinine urine électrophorèse diagnostic infection http://aims.fao.org/aos/agrovoc/c_2963 http://aims.fao.org/aos/agrovoc/c_1547 http://aims.fao.org/aos/agrovoc/c_13628 http://aims.fao.org/aos/agrovoc/c_1953 http://aims.fao.org/aos/agrovoc/c_8103 http://aims.fao.org/aos/agrovoc/c_2523 http://aims.fao.org/aos/agrovoc/c_2238 http://aims.fao.org/aos/agrovoc/c_3852 Pays de l'Union européenne Cambodge http://aims.fao.org/aos/agrovoc/c_36735 http://aims.fao.org/aos/agrovoc/c_4073 Objectives: This study aimed to investigate proteinuria occurring during dengue disease in children and assess if measurement of this parameter can help physicians in the clinical management of patients. Methods: Proteinuria was assessed by dipstick and quantified by urine protein:creatinine ratio (UPCR) in samples from patients hospitalized with a confirmed dengue infection and in healthy controls. Results: The dipstick tested positive in 42.9% of the patients presenting at hospital with dengue versus 20.0% in healthy controls. UPCR increased during the critical phase of the disease; peaking one week after fever onset then decreasing as the patients recovered. Patients with warnings signs or severe dengue were more likely to present with proteinuria detected by UPCR at the time of hospital admission compared to patients without warning signs. The sensitivity of this marker, however, was limited as only 16.1% of the patients with warning signs had proteinuria. Conclusions: Urine dipstick and UPCR do not seem to be very valuable for the triage of the patients at the time of the initial consultation but the observation of a decrease of the UPCR during the course of the illness appears to indicate an evolution towards recovery. article info:eu-repo/semantics/article Journal Article info:eu-repo/semantics/publishedVersion http://agritrop.cirad.fr/583100/1/1-s2.0-S1201971216316678-main.pdf text Cirad license info:eu-repo/semantics/openAccess https://agritrop.cirad.fr/mention_legale.html https://doi.org/10.1016/j.ijid.2016.12.022 10.1016/j.ijid.2016.12.022 info:eu-repo/semantics/altIdentifier/doi/10.1016/j.ijid.2016.12.022 info:eu-repo/semantics/altIdentifier/purl/https://doi.org/10.1016/j.ijid.2016.12.022 info:eu-repo/grantAgreement/EC/FP7/282378//(EU) Dengue research Framework for Resisting Epidemics in Europe/DENFREE |
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000 - Autres thèmes L73 - Maladies des animaux U30 - Méthodes de recherche flavivirus enfant protéinurie créatinine urine électrophorèse diagnostic infection http://aims.fao.org/aos/agrovoc/c_2963 http://aims.fao.org/aos/agrovoc/c_1547 http://aims.fao.org/aos/agrovoc/c_13628 http://aims.fao.org/aos/agrovoc/c_1953 http://aims.fao.org/aos/agrovoc/c_8103 http://aims.fao.org/aos/agrovoc/c_2523 http://aims.fao.org/aos/agrovoc/c_2238 http://aims.fao.org/aos/agrovoc/c_3852 http://aims.fao.org/aos/agrovoc/c_36735 http://aims.fao.org/aos/agrovoc/c_4073 000 - Autres thèmes L73 - Maladies des animaux U30 - Méthodes de recherche flavivirus enfant protéinurie créatinine urine électrophorèse diagnostic infection http://aims.fao.org/aos/agrovoc/c_2963 http://aims.fao.org/aos/agrovoc/c_1547 http://aims.fao.org/aos/agrovoc/c_13628 http://aims.fao.org/aos/agrovoc/c_1953 http://aims.fao.org/aos/agrovoc/c_8103 http://aims.fao.org/aos/agrovoc/c_2523 http://aims.fao.org/aos/agrovoc/c_2238 http://aims.fao.org/aos/agrovoc/c_3852 http://aims.fao.org/aos/agrovoc/c_36735 http://aims.fao.org/aos/agrovoc/c_4073 |
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000 - Autres thèmes L73 - Maladies des animaux U30 - Méthodes de recherche flavivirus enfant protéinurie créatinine urine électrophorèse diagnostic infection http://aims.fao.org/aos/agrovoc/c_2963 http://aims.fao.org/aos/agrovoc/c_1547 http://aims.fao.org/aos/agrovoc/c_13628 http://aims.fao.org/aos/agrovoc/c_1953 http://aims.fao.org/aos/agrovoc/c_8103 http://aims.fao.org/aos/agrovoc/c_2523 http://aims.fao.org/aos/agrovoc/c_2238 http://aims.fao.org/aos/agrovoc/c_3852 http://aims.fao.org/aos/agrovoc/c_36735 http://aims.fao.org/aos/agrovoc/c_4073 000 - Autres thèmes L73 - Maladies des animaux U30 - Méthodes de recherche flavivirus enfant protéinurie créatinine urine électrophorèse diagnostic infection http://aims.fao.org/aos/agrovoc/c_2963 http://aims.fao.org/aos/agrovoc/c_1547 http://aims.fao.org/aos/agrovoc/c_13628 http://aims.fao.org/aos/agrovoc/c_1953 http://aims.fao.org/aos/agrovoc/c_8103 http://aims.fao.org/aos/agrovoc/c_2523 http://aims.fao.org/aos/agrovoc/c_2238 http://aims.fao.org/aos/agrovoc/c_3852 http://aims.fao.org/aos/agrovoc/c_36735 http://aims.fao.org/aos/agrovoc/c_4073 Andries, Anne-Claire Duong, Veasna Cappelle, Julien Ong, Sivuth Kerleguer, Alexandra Ly, Sowath Tarantola, Arnaud Horwood, Paul Sakuntabhai, Anavaj Dussart, Philippe Buchy, Philippe Proteinuria during dengue fever in children |
description |
Objectives: This study aimed to investigate proteinuria occurring during dengue disease in children and assess if measurement of this parameter can help physicians in the clinical management of patients. Methods: Proteinuria was assessed by dipstick and quantified by urine protein:creatinine ratio (UPCR) in samples from patients hospitalized with a confirmed dengue infection and in healthy controls. Results: The dipstick tested positive in 42.9% of the patients presenting at hospital with dengue versus 20.0% in healthy controls. UPCR increased during the critical phase of the disease; peaking one week after fever onset then decreasing as the patients recovered. Patients with warnings signs or severe dengue were more likely to present with proteinuria detected by UPCR at the time of hospital admission compared to patients without warning signs. The sensitivity of this marker, however, was limited as only 16.1% of the patients with warning signs had proteinuria. Conclusions: Urine dipstick and UPCR do not seem to be very valuable for the triage of the patients at the time of the initial consultation but the observation of a decrease of the UPCR during the course of the illness appears to indicate an evolution towards recovery. |
format |
article |
topic_facet |
000 - Autres thèmes L73 - Maladies des animaux U30 - Méthodes de recherche flavivirus enfant protéinurie créatinine urine électrophorèse diagnostic infection http://aims.fao.org/aos/agrovoc/c_2963 http://aims.fao.org/aos/agrovoc/c_1547 http://aims.fao.org/aos/agrovoc/c_13628 http://aims.fao.org/aos/agrovoc/c_1953 http://aims.fao.org/aos/agrovoc/c_8103 http://aims.fao.org/aos/agrovoc/c_2523 http://aims.fao.org/aos/agrovoc/c_2238 http://aims.fao.org/aos/agrovoc/c_3852 http://aims.fao.org/aos/agrovoc/c_36735 http://aims.fao.org/aos/agrovoc/c_4073 |
author |
Andries, Anne-Claire Duong, Veasna Cappelle, Julien Ong, Sivuth Kerleguer, Alexandra Ly, Sowath Tarantola, Arnaud Horwood, Paul Sakuntabhai, Anavaj Dussart, Philippe Buchy, Philippe |
author_facet |
Andries, Anne-Claire Duong, Veasna Cappelle, Julien Ong, Sivuth Kerleguer, Alexandra Ly, Sowath Tarantola, Arnaud Horwood, Paul Sakuntabhai, Anavaj Dussart, Philippe Buchy, Philippe |
author_sort |
Andries, Anne-Claire |
title |
Proteinuria during dengue fever in children |
title_short |
Proteinuria during dengue fever in children |
title_full |
Proteinuria during dengue fever in children |
title_fullStr |
Proteinuria during dengue fever in children |
title_full_unstemmed |
Proteinuria during dengue fever in children |
title_sort |
proteinuria during dengue fever in children |
url |
http://agritrop.cirad.fr/583100/ http://agritrop.cirad.fr/583100/1/1-s2.0-S1201971216316678-main.pdf |
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