Rodents and risk in the Mekong Delta of Vietnam: Seroprevalence of selected zoonotic viruses in rodents and humans
In the Mekong Delta in southern Vietnam, rats are commonly traded in wet markets and sold live for food consumption. We investigated seroprevalence to selected groups of rodent-borne viruses among human populations with high levels of animal exposure and among co-located rodent populations. The indirect fluorescence antibody test (IFAT) was used to determine seropositivity to representative reference strains of hantaviruses (Dobrava virus [DOBV], Seoul virus [SEOV]), cowpox virus, arenaviruses (lymphocytic choriomeningitis virus [LCMV]), flaviviruses (tick-borne encephalitis virus [TBEV]), and rodent parechoviruses (Ljungan virus), using sera from 245 humans living in Dong Thap Province and 275 rodents representing the five common rodent species sold in wet markets and present in peridomestic and farm settings. Combined seropositivity to DOBV and SEOV among the rodents and humans was 6.9% (19/275) and 3.7% (9/245), respectively; 1.1% (3/275) and 4.5% (11/245) to cowpox virus; 5.4% (15/275) and 47.3% (116/245) for TBEV; and exposure to Ljungan virus was 18.8% (46/245) in humans, but 0% in rodents. Very little seroreactivity was observed to LCMV in either rodents (1/275, 0.4%) or humans (2/245, 0.8%). Molecular screening of rodent liver tissues using consensus primers for flaviviruses did not yield any amplicons, whereas molecular screening of rodent lung tissues for hantavirus yielded one hantavirus sequence (SEOV). In summary, these results indicate low to moderate levels of endemic hantavirus circulation, possible circulation of a flavivirus in rodent reservoirs, and the first available data on human exposures to parechoviruses in Vietnam. Although the current evidence suggests only limited exposure of humans to known rodent-borne diseases, further research is warranted to assess public health implications of the rodent trade.
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L72 - Organismes nuisibles des animaux L73 - Maladies des animaux S50 - Santé humaine rongeur Rattus Bandicota genre humain zoonose flavivirus Arenaviridae Picornaviridae hantavirus Orthopoxvirus sérologie virologie épidémiologie transmission des maladies maladie transmise par vecteur santé publique santé animale Enquête pathologique Rattus norvegicus http://aims.fao.org/aos/agrovoc/c_13948 http://aims.fao.org/aos/agrovoc/c_15663 http://aims.fao.org/aos/agrovoc/c_33301 http://aims.fao.org/aos/agrovoc/c_4586 http://aims.fao.org/aos/agrovoc/c_8530 http://aims.fao.org/aos/agrovoc/c_2963 http://aims.fao.org/aos/agrovoc/c_598 http://aims.fao.org/aos/agrovoc/c_5866 http://aims.fao.org/aos/agrovoc/c_35746 http://aims.fao.org/aos/agrovoc/c_5431 http://aims.fao.org/aos/agrovoc/c_27081 http://aims.fao.org/aos/agrovoc/c_8259 http://aims.fao.org/aos/agrovoc/c_2615 http://aims.fao.org/aos/agrovoc/c_2329 http://aims.fao.org/aos/agrovoc/c_34142 http://aims.fao.org/aos/agrovoc/c_6349 http://aims.fao.org/aos/agrovoc/c_431 http://aims.fao.org/aos/agrovoc/c_28665 http://aims.fao.org/aos/agrovoc/c_f9823b8f http://aims.fao.org/aos/agrovoc/c_8227 http://aims.fao.org/aos/agrovoc/c_29734 L72 - Organismes nuisibles des animaux L73 - Maladies des animaux S50 - Santé humaine rongeur Rattus Bandicota genre humain zoonose flavivirus Arenaviridae Picornaviridae hantavirus Orthopoxvirus sérologie virologie épidémiologie transmission des maladies maladie transmise par vecteur santé publique santé animale Enquête pathologique Rattus norvegicus http://aims.fao.org/aos/agrovoc/c_13948 http://aims.fao.org/aos/agrovoc/c_15663 http://aims.fao.org/aos/agrovoc/c_33301 http://aims.fao.org/aos/agrovoc/c_4586 http://aims.fao.org/aos/agrovoc/c_8530 http://aims.fao.org/aos/agrovoc/c_2963 http://aims.fao.org/aos/agrovoc/c_598 http://aims.fao.org/aos/agrovoc/c_5866 http://aims.fao.org/aos/agrovoc/c_35746 http://aims.fao.org/aos/agrovoc/c_5431 http://aims.fao.org/aos/agrovoc/c_27081 http://aims.fao.org/aos/agrovoc/c_8259 http://aims.fao.org/aos/agrovoc/c_2615 http://aims.fao.org/aos/agrovoc/c_2329 http://aims.fao.org/aos/agrovoc/c_34142 http://aims.fao.org/aos/agrovoc/c_6349 http://aims.fao.org/aos/agrovoc/c_431 http://aims.fao.org/aos/agrovoc/c_28665 http://aims.fao.org/aos/agrovoc/c_f9823b8f http://aims.fao.org/aos/agrovoc/c_8227 http://aims.fao.org/aos/agrovoc/c_29734 |
spellingShingle |
L72 - Organismes nuisibles des animaux L73 - Maladies des animaux S50 - Santé humaine rongeur Rattus Bandicota genre humain zoonose flavivirus Arenaviridae Picornaviridae hantavirus Orthopoxvirus sérologie virologie épidémiologie transmission des maladies maladie transmise par vecteur santé publique santé animale Enquête pathologique Rattus norvegicus http://aims.fao.org/aos/agrovoc/c_13948 http://aims.fao.org/aos/agrovoc/c_15663 http://aims.fao.org/aos/agrovoc/c_33301 http://aims.fao.org/aos/agrovoc/c_4586 http://aims.fao.org/aos/agrovoc/c_8530 http://aims.fao.org/aos/agrovoc/c_2963 http://aims.fao.org/aos/agrovoc/c_598 http://aims.fao.org/aos/agrovoc/c_5866 http://aims.fao.org/aos/agrovoc/c_35746 http://aims.fao.org/aos/agrovoc/c_5431 http://aims.fao.org/aos/agrovoc/c_27081 http://aims.fao.org/aos/agrovoc/c_8259 http://aims.fao.org/aos/agrovoc/c_2615 http://aims.fao.org/aos/agrovoc/c_2329 http://aims.fao.org/aos/agrovoc/c_34142 http://aims.fao.org/aos/agrovoc/c_6349 http://aims.fao.org/aos/agrovoc/c_431 http://aims.fao.org/aos/agrovoc/c_28665 http://aims.fao.org/aos/agrovoc/c_f9823b8f http://aims.fao.org/aos/agrovoc/c_8227 http://aims.fao.org/aos/agrovoc/c_29734 L72 - Organismes nuisibles des animaux L73 - Maladies des animaux S50 - Santé humaine rongeur Rattus Bandicota genre humain zoonose flavivirus Arenaviridae Picornaviridae hantavirus Orthopoxvirus sérologie virologie épidémiologie transmission des maladies maladie transmise par vecteur santé publique santé animale Enquête pathologique Rattus norvegicus http://aims.fao.org/aos/agrovoc/c_13948 http://aims.fao.org/aos/agrovoc/c_15663 http://aims.fao.org/aos/agrovoc/c_33301 http://aims.fao.org/aos/agrovoc/c_4586 http://aims.fao.org/aos/agrovoc/c_8530 http://aims.fao.org/aos/agrovoc/c_2963 http://aims.fao.org/aos/agrovoc/c_598 http://aims.fao.org/aos/agrovoc/c_5866 http://aims.fao.org/aos/agrovoc/c_35746 http://aims.fao.org/aos/agrovoc/c_5431 http://aims.fao.org/aos/agrovoc/c_27081 http://aims.fao.org/aos/agrovoc/c_8259 http://aims.fao.org/aos/agrovoc/c_2615 http://aims.fao.org/aos/agrovoc/c_2329 http://aims.fao.org/aos/agrovoc/c_34142 http://aims.fao.org/aos/agrovoc/c_6349 http://aims.fao.org/aos/agrovoc/c_431 http://aims.fao.org/aos/agrovoc/c_28665 http://aims.fao.org/aos/agrovoc/c_f9823b8f http://aims.fao.org/aos/agrovoc/c_8227 http://aims.fao.org/aos/agrovoc/c_29734 Van Cuong, Nguyen Carrique-Mas, Juan Be Hien, Vo Ngoc An, Nguyen Tri Tue, Ngo Lam Anh, Nguyet Hong Anh, Pham The Phuc, Nguyen Baker, Stephen Voutilainen, Liina Jääskejäinen, Anne Huhtamo, Eili Utriainen, Mira Sironen, Tarja Vaheri, Antti Henttonen, Heikki Vapalahti, Olli Chaval, Yannick Morand, Serge Bryant, Juliet Rodents and risk in the Mekong Delta of Vietnam: Seroprevalence of selected zoonotic viruses in rodents and humans |
description |
In the Mekong Delta in southern Vietnam, rats are commonly traded in wet markets and sold live for food consumption. We investigated seroprevalence to selected groups of rodent-borne viruses among human populations with high levels of animal exposure and among co-located rodent populations. The indirect fluorescence antibody test (IFAT) was used to determine seropositivity to representative reference strains of hantaviruses (Dobrava virus [DOBV], Seoul virus [SEOV]), cowpox virus, arenaviruses (lymphocytic choriomeningitis virus [LCMV]), flaviviruses (tick-borne encephalitis virus [TBEV]), and rodent parechoviruses (Ljungan virus), using sera from 245 humans living in Dong Thap Province and 275 rodents representing the five common rodent species sold in wet markets and present in peridomestic and farm settings. Combined seropositivity to DOBV and SEOV among the rodents and humans was 6.9% (19/275) and 3.7% (9/245), respectively; 1.1% (3/275) and 4.5% (11/245) to cowpox virus; 5.4% (15/275) and 47.3% (116/245) for TBEV; and exposure to Ljungan virus was 18.8% (46/245) in humans, but 0% in rodents. Very little seroreactivity was observed to LCMV in either rodents (1/275, 0.4%) or humans (2/245, 0.8%). Molecular screening of rodent liver tissues using consensus primers for flaviviruses did not yield any amplicons, whereas molecular screening of rodent lung tissues for hantavirus yielded one hantavirus sequence (SEOV). In summary, these results indicate low to moderate levels of endemic hantavirus circulation, possible circulation of a flavivirus in rodent reservoirs, and the first available data on human exposures to parechoviruses in Vietnam. Although the current evidence suggests only limited exposure of humans to known rodent-borne diseases, further research is warranted to assess public health implications of the rodent trade. |
format |
article |
topic_facet |
L72 - Organismes nuisibles des animaux L73 - Maladies des animaux S50 - Santé humaine rongeur Rattus Bandicota genre humain zoonose flavivirus Arenaviridae Picornaviridae hantavirus Orthopoxvirus sérologie virologie épidémiologie transmission des maladies maladie transmise par vecteur santé publique santé animale Enquête pathologique Rattus norvegicus http://aims.fao.org/aos/agrovoc/c_13948 http://aims.fao.org/aos/agrovoc/c_15663 http://aims.fao.org/aos/agrovoc/c_33301 http://aims.fao.org/aos/agrovoc/c_4586 http://aims.fao.org/aos/agrovoc/c_8530 http://aims.fao.org/aos/agrovoc/c_2963 http://aims.fao.org/aos/agrovoc/c_598 http://aims.fao.org/aos/agrovoc/c_5866 http://aims.fao.org/aos/agrovoc/c_35746 http://aims.fao.org/aos/agrovoc/c_5431 http://aims.fao.org/aos/agrovoc/c_27081 http://aims.fao.org/aos/agrovoc/c_8259 http://aims.fao.org/aos/agrovoc/c_2615 http://aims.fao.org/aos/agrovoc/c_2329 http://aims.fao.org/aos/agrovoc/c_34142 http://aims.fao.org/aos/agrovoc/c_6349 http://aims.fao.org/aos/agrovoc/c_431 http://aims.fao.org/aos/agrovoc/c_28665 http://aims.fao.org/aos/agrovoc/c_f9823b8f http://aims.fao.org/aos/agrovoc/c_8227 http://aims.fao.org/aos/agrovoc/c_29734 |
author |
Van Cuong, Nguyen Carrique-Mas, Juan Be Hien, Vo Ngoc An, Nguyen Tri Tue, Ngo Lam Anh, Nguyet Hong Anh, Pham The Phuc, Nguyen Baker, Stephen Voutilainen, Liina Jääskejäinen, Anne Huhtamo, Eili Utriainen, Mira Sironen, Tarja Vaheri, Antti Henttonen, Heikki Vapalahti, Olli Chaval, Yannick Morand, Serge Bryant, Juliet |
author_facet |
Van Cuong, Nguyen Carrique-Mas, Juan Be Hien, Vo Ngoc An, Nguyen Tri Tue, Ngo Lam Anh, Nguyet Hong Anh, Pham The Phuc, Nguyen Baker, Stephen Voutilainen, Liina Jääskejäinen, Anne Huhtamo, Eili Utriainen, Mira Sironen, Tarja Vaheri, Antti Henttonen, Heikki Vapalahti, Olli Chaval, Yannick Morand, Serge Bryant, Juliet |
author_sort |
Van Cuong, Nguyen |
title |
Rodents and risk in the Mekong Delta of Vietnam: Seroprevalence of selected zoonotic viruses in rodents and humans |
title_short |
Rodents and risk in the Mekong Delta of Vietnam: Seroprevalence of selected zoonotic viruses in rodents and humans |
title_full |
Rodents and risk in the Mekong Delta of Vietnam: Seroprevalence of selected zoonotic viruses in rodents and humans |
title_fullStr |
Rodents and risk in the Mekong Delta of Vietnam: Seroprevalence of selected zoonotic viruses in rodents and humans |
title_full_unstemmed |
Rodents and risk in the Mekong Delta of Vietnam: Seroprevalence of selected zoonotic viruses in rodents and humans |
title_sort |
rodents and risk in the mekong delta of vietnam: seroprevalence of selected zoonotic viruses in rodents and humans |
url |
http://agritrop.cirad.fr/575482/ http://agritrop.cirad.fr/575482/1/document_575482.pdf |
work_keys_str_mv |
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dig-cirad-fr-5754822024-01-28T22:33:23Z http://agritrop.cirad.fr/575482/ http://agritrop.cirad.fr/575482/ Rodents and risk in the Mekong Delta of Vietnam: Seroprevalence of selected zoonotic viruses in rodents and humans. Van Cuong Nguyen, Carrique-Mas Juan, Be Hien Vo, Ngoc An Nguyen, Tri Tue Ngo, Lam Anh Nguyet, Hong Anh Pham, The Phuc Nguyen, Baker Stephen, Voutilainen Liina, Jääskejäinen Anne, Huhtamo Eili, Utriainen Mira, Sironen Tarja, Vaheri Antti, Henttonen Heikki, Vapalahti Olli, Chaval Yannick, Morand Serge, Bryant Juliet. 2015. Vector Borne and Zoonotic Diseases, 15 (1) : 65-72.https://doi.org/10.1089/vbz.2014.1603 <https://doi.org/10.1089/vbz.2014.1603> Rodents and risk in the Mekong Delta of Vietnam: Seroprevalence of selected zoonotic viruses in rodents and humans Van Cuong, Nguyen Carrique-Mas, Juan Be Hien, Vo Ngoc An, Nguyen Tri Tue, Ngo Lam Anh, Nguyet Hong Anh, Pham The Phuc, Nguyen Baker, Stephen Voutilainen, Liina Jääskejäinen, Anne Huhtamo, Eili Utriainen, Mira Sironen, Tarja Vaheri, Antti Henttonen, Heikki Vapalahti, Olli Chaval, Yannick Morand, Serge Bryant, Juliet eng 2015 Vector Borne and Zoonotic Diseases L72 - Organismes nuisibles des animaux L73 - Maladies des animaux S50 - Santé humaine rongeur Rattus Bandicota genre humain zoonose flavivirus Arenaviridae Picornaviridae hantavirus Orthopoxvirus sérologie virologie épidémiologie transmission des maladies maladie transmise par vecteur santé publique santé animale Enquête pathologique Rattus norvegicus http://aims.fao.org/aos/agrovoc/c_13948 http://aims.fao.org/aos/agrovoc/c_15663 http://aims.fao.org/aos/agrovoc/c_33301 http://aims.fao.org/aos/agrovoc/c_4586 http://aims.fao.org/aos/agrovoc/c_8530 http://aims.fao.org/aos/agrovoc/c_2963 http://aims.fao.org/aos/agrovoc/c_598 http://aims.fao.org/aos/agrovoc/c_5866 http://aims.fao.org/aos/agrovoc/c_35746 http://aims.fao.org/aos/agrovoc/c_5431 http://aims.fao.org/aos/agrovoc/c_27081 http://aims.fao.org/aos/agrovoc/c_8259 http://aims.fao.org/aos/agrovoc/c_2615 http://aims.fao.org/aos/agrovoc/c_2329 http://aims.fao.org/aos/agrovoc/c_34142 http://aims.fao.org/aos/agrovoc/c_6349 http://aims.fao.org/aos/agrovoc/c_431 http://aims.fao.org/aos/agrovoc/c_28665 http://aims.fao.org/aos/agrovoc/c_f9823b8f Viet Nam Mékong http://aims.fao.org/aos/agrovoc/c_8227 http://aims.fao.org/aos/agrovoc/c_29734 In the Mekong Delta in southern Vietnam, rats are commonly traded in wet markets and sold live for food consumption. We investigated seroprevalence to selected groups of rodent-borne viruses among human populations with high levels of animal exposure and among co-located rodent populations. The indirect fluorescence antibody test (IFAT) was used to determine seropositivity to representative reference strains of hantaviruses (Dobrava virus [DOBV], Seoul virus [SEOV]), cowpox virus, arenaviruses (lymphocytic choriomeningitis virus [LCMV]), flaviviruses (tick-borne encephalitis virus [TBEV]), and rodent parechoviruses (Ljungan virus), using sera from 245 humans living in Dong Thap Province and 275 rodents representing the five common rodent species sold in wet markets and present in peridomestic and farm settings. Combined seropositivity to DOBV and SEOV among the rodents and humans was 6.9% (19/275) and 3.7% (9/245), respectively; 1.1% (3/275) and 4.5% (11/245) to cowpox virus; 5.4% (15/275) and 47.3% (116/245) for TBEV; and exposure to Ljungan virus was 18.8% (46/245) in humans, but 0% in rodents. Very little seroreactivity was observed to LCMV in either rodents (1/275, 0.4%) or humans (2/245, 0.8%). Molecular screening of rodent liver tissues using consensus primers for flaviviruses did not yield any amplicons, whereas molecular screening of rodent lung tissues for hantavirus yielded one hantavirus sequence (SEOV). In summary, these results indicate low to moderate levels of endemic hantavirus circulation, possible circulation of a flavivirus in rodent reservoirs, and the first available data on human exposures to parechoviruses in Vietnam. Although the current evidence suggests only limited exposure of humans to known rodent-borne diseases, further research is warranted to assess public health implications of the rodent trade. article info:eu-repo/semantics/article Journal Article info:eu-repo/semantics/publishedVersion http://agritrop.cirad.fr/575482/1/document_575482.pdf application/pdf cc_by info:eu-repo/semantics/openAccess https://creativecommons.org/licenses/by/4.0/ https://doi.org/10.1089/vbz.2014.1603 10.1089/vbz.2014.1603 info:eu-repo/semantics/altIdentifier/doi/10.1089/vbz.2014.1603 info:eu-repo/semantics/altIdentifier/purl/https://doi.org/10.1089/vbz.2014.1603 |