Broad-coverage molecular epidemiology of Orientia tsutsugamushi in Thailand
Orientia tsutsugamushi, an obligate intracellular bacterium closely related to the genus Rickettsia, is the causative agent of scrub typhus, a major cause of febrile illness in rural areas of Asia-Pacific region. Scrub typhus is transmitted by the bite of infected mites of the genus Leptotrombidium. The region of the 56-kDa TSA gene spanning from variable domain I (VDI) to variable domain IV (VDIV) was sequenced and used for genotyping 77 O. tsutsugamushi samples from human patients confirmed with scrub typhus from 2001 to 2003 and 2009 to 2010 in different regions of Thailand. These sequences were also compared to previously published 56-kDa TSA sequences. Only 4 genotypes out of 8 previously reported in Thailand were identified, i.e. Karp, JG-v, TA763 and Kato, respectively. Two strains were not associated with known genotypes but were closely related to Taiwanese strains. The Karp genotype was confirmed as the predominant clade. The JG-v and TA763 genotypes, in contrast to other studies, also were found. The genotype TA716 was not found, except for one strain previously described.
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Subjects: | L73 - Maladies des animaux, S50 - Santé humaine, Rickettsiales, épidémiologie, génotype, identification, antigène, phylogénie, genre humain, variation génétique, http://aims.fao.org/aos/agrovoc/c_6602, http://aims.fao.org/aos/agrovoc/c_2615, http://aims.fao.org/aos/agrovoc/c_3225, http://aims.fao.org/aos/agrovoc/c_3791, http://aims.fao.org/aos/agrovoc/c_504, http://aims.fao.org/aos/agrovoc/c_13325, http://aims.fao.org/aos/agrovoc/c_4586, http://aims.fao.org/aos/agrovoc/c_15975, http://aims.fao.org/aos/agrovoc/c_7701, |
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dig-cirad-fr-5700942024-01-28T21:34:19Z http://agritrop.cirad.fr/570094/ http://agritrop.cirad.fr/570094/ Broad-coverage molecular epidemiology of Orientia tsutsugamushi in Thailand. Wongprompitak Patimaporn, Anukool Wichittra, Wongsawat Ekkarat, Silpasakorn Saowalak, Duong Veasna, Buchy Philippe, Morand Serge, Frutos Roger, Ekpo Pattama, Suputtamongkol Yupin. 2013. Infection, Genetics and Evolution, 15, spec. : 53-58. International Giardia and Cryptosporidium Conference. 4, Wellington, Afrique du Sud, 30 Janvier 2012/3 Février 2012.https://doi.org/10.1016/j.meegid.2011.06.008 <https://doi.org/10.1016/j.meegid.2011.06.008> Broad-coverage molecular epidemiology of Orientia tsutsugamushi in Thailand Wongprompitak, Patimaporn Anukool, Wichittra Wongsawat, Ekkarat Silpasakorn, Saowalak Duong, Veasna Buchy, Philippe Morand, Serge Frutos, Roger Ekpo, Pattama Suputtamongkol, Yupin eng 2013 Infection, Genetics and Evolution L73 - Maladies des animaux S50 - Santé humaine Rickettsiales épidémiologie génotype identification antigène phylogénie genre humain variation génétique http://aims.fao.org/aos/agrovoc/c_6602 http://aims.fao.org/aos/agrovoc/c_2615 http://aims.fao.org/aos/agrovoc/c_3225 http://aims.fao.org/aos/agrovoc/c_3791 http://aims.fao.org/aos/agrovoc/c_504 http://aims.fao.org/aos/agrovoc/c_13325 http://aims.fao.org/aos/agrovoc/c_4586 http://aims.fao.org/aos/agrovoc/c_15975 Thaïlande http://aims.fao.org/aos/agrovoc/c_7701 Orientia tsutsugamushi, an obligate intracellular bacterium closely related to the genus Rickettsia, is the causative agent of scrub typhus, a major cause of febrile illness in rural areas of Asia-Pacific region. Scrub typhus is transmitted by the bite of infected mites of the genus Leptotrombidium. The region of the 56-kDa TSA gene spanning from variable domain I (VDI) to variable domain IV (VDIV) was sequenced and used for genotyping 77 O. tsutsugamushi samples from human patients confirmed with scrub typhus from 2001 to 2003 and 2009 to 2010 in different regions of Thailand. These sequences were also compared to previously published 56-kDa TSA sequences. Only 4 genotypes out of 8 previously reported in Thailand were identified, i.e. Karp, JG-v, TA763 and Kato, respectively. Two strains were not associated with known genotypes but were closely related to Taiwanese strains. The Karp genotype was confirmed as the predominant clade. The JG-v and TA763 genotypes, in contrast to other studies, also were found. The genotype TA716 was not found, except for one strain previously described. article info:eu-repo/semantics/article Journal Article info:eu-repo/semantics/publishedVersion http://agritrop.cirad.fr/570094/1/document_570094.pdf application/pdf Cirad license info:eu-repo/semantics/restrictedAccess https://agritrop.cirad.fr/mention_legale.html https://doi.org/10.1016/j.meegid.2011.06.008 10.1016/j.meegid.2011.06.008 info:eu-repo/semantics/altIdentifier/doi/10.1016/j.meegid.2011.06.008 info:eu-repo/semantics/altIdentifier/purl/https://doi.org/10.1016/j.meegid.2011.06.008 |
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L73 - Maladies des animaux S50 - Santé humaine Rickettsiales épidémiologie génotype identification antigène phylogénie genre humain variation génétique http://aims.fao.org/aos/agrovoc/c_6602 http://aims.fao.org/aos/agrovoc/c_2615 http://aims.fao.org/aos/agrovoc/c_3225 http://aims.fao.org/aos/agrovoc/c_3791 http://aims.fao.org/aos/agrovoc/c_504 http://aims.fao.org/aos/agrovoc/c_13325 http://aims.fao.org/aos/agrovoc/c_4586 http://aims.fao.org/aos/agrovoc/c_15975 http://aims.fao.org/aos/agrovoc/c_7701 L73 - Maladies des animaux S50 - Santé humaine Rickettsiales épidémiologie génotype identification antigène phylogénie genre humain variation génétique http://aims.fao.org/aos/agrovoc/c_6602 http://aims.fao.org/aos/agrovoc/c_2615 http://aims.fao.org/aos/agrovoc/c_3225 http://aims.fao.org/aos/agrovoc/c_3791 http://aims.fao.org/aos/agrovoc/c_504 http://aims.fao.org/aos/agrovoc/c_13325 http://aims.fao.org/aos/agrovoc/c_4586 http://aims.fao.org/aos/agrovoc/c_15975 http://aims.fao.org/aos/agrovoc/c_7701 |
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L73 - Maladies des animaux S50 - Santé humaine Rickettsiales épidémiologie génotype identification antigène phylogénie genre humain variation génétique http://aims.fao.org/aos/agrovoc/c_6602 http://aims.fao.org/aos/agrovoc/c_2615 http://aims.fao.org/aos/agrovoc/c_3225 http://aims.fao.org/aos/agrovoc/c_3791 http://aims.fao.org/aos/agrovoc/c_504 http://aims.fao.org/aos/agrovoc/c_13325 http://aims.fao.org/aos/agrovoc/c_4586 http://aims.fao.org/aos/agrovoc/c_15975 http://aims.fao.org/aos/agrovoc/c_7701 L73 - Maladies des animaux S50 - Santé humaine Rickettsiales épidémiologie génotype identification antigène phylogénie genre humain variation génétique http://aims.fao.org/aos/agrovoc/c_6602 http://aims.fao.org/aos/agrovoc/c_2615 http://aims.fao.org/aos/agrovoc/c_3225 http://aims.fao.org/aos/agrovoc/c_3791 http://aims.fao.org/aos/agrovoc/c_504 http://aims.fao.org/aos/agrovoc/c_13325 http://aims.fao.org/aos/agrovoc/c_4586 http://aims.fao.org/aos/agrovoc/c_15975 http://aims.fao.org/aos/agrovoc/c_7701 Wongprompitak, Patimaporn Anukool, Wichittra Wongsawat, Ekkarat Silpasakorn, Saowalak Duong, Veasna Buchy, Philippe Morand, Serge Frutos, Roger Ekpo, Pattama Suputtamongkol, Yupin Broad-coverage molecular epidemiology of Orientia tsutsugamushi in Thailand |
description |
Orientia tsutsugamushi, an obligate intracellular bacterium closely related to the genus Rickettsia, is the causative agent of scrub typhus, a major cause of febrile illness in rural areas of Asia-Pacific region. Scrub typhus is transmitted by the bite of infected mites of the genus Leptotrombidium. The region of the 56-kDa TSA gene spanning from variable domain I (VDI) to variable domain IV (VDIV) was sequenced and used for genotyping 77 O. tsutsugamushi samples from human patients confirmed with scrub typhus from 2001 to 2003 and 2009 to 2010 in different regions of Thailand. These sequences were also compared to previously published 56-kDa TSA sequences. Only 4 genotypes out of 8 previously reported in Thailand were identified, i.e. Karp, JG-v, TA763 and Kato, respectively. Two strains were not associated with known genotypes but were closely related to Taiwanese strains. The Karp genotype was confirmed as the predominant clade. The JG-v and TA763 genotypes, in contrast to other studies, also were found. The genotype TA716 was not found, except for one strain previously described. |
format |
article |
topic_facet |
L73 - Maladies des animaux S50 - Santé humaine Rickettsiales épidémiologie génotype identification antigène phylogénie genre humain variation génétique http://aims.fao.org/aos/agrovoc/c_6602 http://aims.fao.org/aos/agrovoc/c_2615 http://aims.fao.org/aos/agrovoc/c_3225 http://aims.fao.org/aos/agrovoc/c_3791 http://aims.fao.org/aos/agrovoc/c_504 http://aims.fao.org/aos/agrovoc/c_13325 http://aims.fao.org/aos/agrovoc/c_4586 http://aims.fao.org/aos/agrovoc/c_15975 http://aims.fao.org/aos/agrovoc/c_7701 |
author |
Wongprompitak, Patimaporn Anukool, Wichittra Wongsawat, Ekkarat Silpasakorn, Saowalak Duong, Veasna Buchy, Philippe Morand, Serge Frutos, Roger Ekpo, Pattama Suputtamongkol, Yupin |
author_facet |
Wongprompitak, Patimaporn Anukool, Wichittra Wongsawat, Ekkarat Silpasakorn, Saowalak Duong, Veasna Buchy, Philippe Morand, Serge Frutos, Roger Ekpo, Pattama Suputtamongkol, Yupin |
author_sort |
Wongprompitak, Patimaporn |
title |
Broad-coverage molecular epidemiology of Orientia tsutsugamushi in Thailand |
title_short |
Broad-coverage molecular epidemiology of Orientia tsutsugamushi in Thailand |
title_full |
Broad-coverage molecular epidemiology of Orientia tsutsugamushi in Thailand |
title_fullStr |
Broad-coverage molecular epidemiology of Orientia tsutsugamushi in Thailand |
title_full_unstemmed |
Broad-coverage molecular epidemiology of Orientia tsutsugamushi in Thailand |
title_sort |
broad-coverage molecular epidemiology of orientia tsutsugamushi in thailand |
url |
http://agritrop.cirad.fr/570094/ http://agritrop.cirad.fr/570094/1/document_570094.pdf |
work_keys_str_mv |
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