Assessment of glomerular filtration rate in normally hydrated and dehydrated dromedary camel by plasma exogenous creatinine clearance test
The main objective of this study was to assess glomerular filtration rate (GFR) in the camels (Camelus dromedarius) under free water access and dehydration conditions (after a 34 days-period of water deprivation) using plasma exogenous creatinine clearance without urine collection. Trials were carried out on six nonpregnant, non-lactating and healthy female camels. Creatinine was administered as an IV bolus at a dose of 16 mg/kg body weight. Blood samples were collected at predetermined times over 24 h post-injection. Plasma creatinine concentration was analysed using Jaffé method. Creatinine clearance was calculated by pharmacokinetic analysis using a non-compartmental approach. Water deprivation induced a significant 15%- decrease in body weight but did not affect haematocrit and total plasma proteins. Mean corpuscular volume increased and red blood cells number decreased in dehydrated conditions. Dehydration produced a significant 30%-increase in plasma creatinine and mean residence time and a significant 20%-decrease in GFR. In conclusion, water deprivation decreased glomerular filtration and plasma exogenous creatinine clearance test could be used as a practical method for GFR assessment in dromedary camel in field conditions.
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Subjects: | L51 - Physiologie animale - Nutrition, dromadaire, privation d'eau, déshydratation, filtration, rein, physiologie de la nutrition, physiologie animale, Camelus dromedarius, http://aims.fao.org/aos/agrovoc/c_10467, http://aims.fao.org/aos/agrovoc/c_8317, http://aims.fao.org/aos/agrovoc/c_2162, http://aims.fao.org/aos/agrovoc/c_2900, http://aims.fao.org/aos/agrovoc/c_4099, http://aims.fao.org/aos/agrovoc/c_5275, http://aims.fao.org/aos/agrovoc/c_25187, http://aims.fao.org/aos/agrovoc/c_5a453ce9, http://aims.fao.org/aos/agrovoc/c_4940, |
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dig-cirad-fr-5676082024-01-28T21:11:14Z http://agritrop.cirad.fr/567608/ http://agritrop.cirad.fr/567608/ Assessment of glomerular filtration rate in normally hydrated and dehydrated dromedary camel by plasma exogenous creatinine clearance test. Kamili Asma, Bengoumi Mohammed, Oukessou Mohamed, Faye Bernard, Lefebvre Hervé P.. 2013. Emirates Journal of Food and Agriculture, 25 (4) : 314-319.https://doi.org/10.9755/ejfa.v25i4.15501 <https://doi.org/10.9755/ejfa.v25i4.15501> Assessment of glomerular filtration rate in normally hydrated and dehydrated dromedary camel by plasma exogenous creatinine clearance test Kamili, Asma Bengoumi, Mohammed Oukessou, Mohamed Faye, Bernard Lefebvre, Hervé P. eng 2013 Emirates Journal of Food and Agriculture L51 - Physiologie animale - Nutrition dromadaire privation d'eau déshydratation filtration rein physiologie de la nutrition physiologie animale Camelus dromedarius http://aims.fao.org/aos/agrovoc/c_10467 http://aims.fao.org/aos/agrovoc/c_8317 http://aims.fao.org/aos/agrovoc/c_2162 http://aims.fao.org/aos/agrovoc/c_2900 http://aims.fao.org/aos/agrovoc/c_4099 http://aims.fao.org/aos/agrovoc/c_5275 http://aims.fao.org/aos/agrovoc/c_25187 http://aims.fao.org/aos/agrovoc/c_5a453ce9 Maroc http://aims.fao.org/aos/agrovoc/c_4940 The main objective of this study was to assess glomerular filtration rate (GFR) in the camels (Camelus dromedarius) under free water access and dehydration conditions (after a 34 days-period of water deprivation) using plasma exogenous creatinine clearance without urine collection. Trials were carried out on six nonpregnant, non-lactating and healthy female camels. Creatinine was administered as an IV bolus at a dose of 16 mg/kg body weight. Blood samples were collected at predetermined times over 24 h post-injection. Plasma creatinine concentration was analysed using Jaffé method. Creatinine clearance was calculated by pharmacokinetic analysis using a non-compartmental approach. Water deprivation induced a significant 15%- decrease in body weight but did not affect haematocrit and total plasma proteins. Mean corpuscular volume increased and red blood cells number decreased in dehydrated conditions. Dehydration produced a significant 30%-increase in plasma creatinine and mean residence time and a significant 20%-decrease in GFR. In conclusion, water deprivation decreased glomerular filtration and plasma exogenous creatinine clearance test could be used as a practical method for GFR assessment in dromedary camel in field conditions. article info:eu-repo/semantics/article Journal Article info:eu-repo/semantics/publishedVersion http://agritrop.cirad.fr/567608/1/document_567608.pdf application/pdf Cirad license info:eu-repo/semantics/openAccess https://agritrop.cirad.fr/mention_legale.html https://doi.org/10.9755/ejfa.v25i4.15501 10.9755/ejfa.v25i4.15501 info:eu-repo/semantics/altIdentifier/doi/10.9755/ejfa.v25i4.15501 info:eu-repo/semantics/altIdentifier/purl/https://doi.org/10.9755/ejfa.v25i4.15501 |
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L51 - Physiologie animale - Nutrition dromadaire privation d'eau déshydratation filtration rein physiologie de la nutrition physiologie animale Camelus dromedarius http://aims.fao.org/aos/agrovoc/c_10467 http://aims.fao.org/aos/agrovoc/c_8317 http://aims.fao.org/aos/agrovoc/c_2162 http://aims.fao.org/aos/agrovoc/c_2900 http://aims.fao.org/aos/agrovoc/c_4099 http://aims.fao.org/aos/agrovoc/c_5275 http://aims.fao.org/aos/agrovoc/c_25187 http://aims.fao.org/aos/agrovoc/c_5a453ce9 http://aims.fao.org/aos/agrovoc/c_4940 L51 - Physiologie animale - Nutrition dromadaire privation d'eau déshydratation filtration rein physiologie de la nutrition physiologie animale Camelus dromedarius http://aims.fao.org/aos/agrovoc/c_10467 http://aims.fao.org/aos/agrovoc/c_8317 http://aims.fao.org/aos/agrovoc/c_2162 http://aims.fao.org/aos/agrovoc/c_2900 http://aims.fao.org/aos/agrovoc/c_4099 http://aims.fao.org/aos/agrovoc/c_5275 http://aims.fao.org/aos/agrovoc/c_25187 http://aims.fao.org/aos/agrovoc/c_5a453ce9 http://aims.fao.org/aos/agrovoc/c_4940 |
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L51 - Physiologie animale - Nutrition dromadaire privation d'eau déshydratation filtration rein physiologie de la nutrition physiologie animale Camelus dromedarius http://aims.fao.org/aos/agrovoc/c_10467 http://aims.fao.org/aos/agrovoc/c_8317 http://aims.fao.org/aos/agrovoc/c_2162 http://aims.fao.org/aos/agrovoc/c_2900 http://aims.fao.org/aos/agrovoc/c_4099 http://aims.fao.org/aos/agrovoc/c_5275 http://aims.fao.org/aos/agrovoc/c_25187 http://aims.fao.org/aos/agrovoc/c_5a453ce9 http://aims.fao.org/aos/agrovoc/c_4940 L51 - Physiologie animale - Nutrition dromadaire privation d'eau déshydratation filtration rein physiologie de la nutrition physiologie animale Camelus dromedarius http://aims.fao.org/aos/agrovoc/c_10467 http://aims.fao.org/aos/agrovoc/c_8317 http://aims.fao.org/aos/agrovoc/c_2162 http://aims.fao.org/aos/agrovoc/c_2900 http://aims.fao.org/aos/agrovoc/c_4099 http://aims.fao.org/aos/agrovoc/c_5275 http://aims.fao.org/aos/agrovoc/c_25187 http://aims.fao.org/aos/agrovoc/c_5a453ce9 http://aims.fao.org/aos/agrovoc/c_4940 Kamili, Asma Bengoumi, Mohammed Oukessou, Mohamed Faye, Bernard Lefebvre, Hervé P. Assessment of glomerular filtration rate in normally hydrated and dehydrated dromedary camel by plasma exogenous creatinine clearance test |
description |
The main objective of this study was to assess glomerular filtration rate (GFR) in the camels (Camelus dromedarius) under free water access and dehydration conditions (after a 34 days-period of water deprivation) using plasma exogenous creatinine clearance without urine collection. Trials were carried out on six nonpregnant, non-lactating and healthy female camels. Creatinine was administered as an IV bolus at a dose of 16 mg/kg body weight. Blood samples were collected at predetermined times over 24 h post-injection. Plasma creatinine concentration was analysed using Jaffé method. Creatinine clearance was calculated by pharmacokinetic analysis using a non-compartmental approach. Water deprivation induced a significant 15%- decrease in body weight but did not affect haematocrit and total plasma proteins. Mean corpuscular volume increased and red blood cells number decreased in dehydrated conditions. Dehydration produced a significant 30%-increase in plasma creatinine and mean residence time and a significant 20%-decrease in GFR. In conclusion, water deprivation decreased glomerular filtration and plasma exogenous creatinine clearance test could be used as a practical method for GFR assessment in dromedary camel in field conditions. |
format |
article |
topic_facet |
L51 - Physiologie animale - Nutrition dromadaire privation d'eau déshydratation filtration rein physiologie de la nutrition physiologie animale Camelus dromedarius http://aims.fao.org/aos/agrovoc/c_10467 http://aims.fao.org/aos/agrovoc/c_8317 http://aims.fao.org/aos/agrovoc/c_2162 http://aims.fao.org/aos/agrovoc/c_2900 http://aims.fao.org/aos/agrovoc/c_4099 http://aims.fao.org/aos/agrovoc/c_5275 http://aims.fao.org/aos/agrovoc/c_25187 http://aims.fao.org/aos/agrovoc/c_5a453ce9 http://aims.fao.org/aos/agrovoc/c_4940 |
author |
Kamili, Asma Bengoumi, Mohammed Oukessou, Mohamed Faye, Bernard Lefebvre, Hervé P. |
author_facet |
Kamili, Asma Bengoumi, Mohammed Oukessou, Mohamed Faye, Bernard Lefebvre, Hervé P. |
author_sort |
Kamili, Asma |
title |
Assessment of glomerular filtration rate in normally hydrated and dehydrated dromedary camel by plasma exogenous creatinine clearance test |
title_short |
Assessment of glomerular filtration rate in normally hydrated and dehydrated dromedary camel by plasma exogenous creatinine clearance test |
title_full |
Assessment of glomerular filtration rate in normally hydrated and dehydrated dromedary camel by plasma exogenous creatinine clearance test |
title_fullStr |
Assessment of glomerular filtration rate in normally hydrated and dehydrated dromedary camel by plasma exogenous creatinine clearance test |
title_full_unstemmed |
Assessment of glomerular filtration rate in normally hydrated and dehydrated dromedary camel by plasma exogenous creatinine clearance test |
title_sort |
assessment of glomerular filtration rate in normally hydrated and dehydrated dromedary camel by plasma exogenous creatinine clearance test |
url |
http://agritrop.cirad.fr/567608/ http://agritrop.cirad.fr/567608/1/document_567608.pdf |
work_keys_str_mv |
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