Protection against Cowdria ruminantium infection in mice with gamma interferon produced in animal cells
We report here that y interferon produced in animal cell culture injected intraperitoneally, efficiently protects mice against Cow£iria ruminantium infection. None of the other cytokines tested exerted any effect. Neutralizing antibodies against the cytokines (anti IL6, anti TNF, anti yIFN), did not modify the course of the disease, indicating that these cytokines do not play any crucial role in the pathology. The results conceming the protective effect of interferon pave the way towards the establishment of a rational selection method for protective antigens.
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Kluwer Academic Publishers
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Subjects: | L73 - Maladies des animaux, souris, Ehrlichia ruminantium, immunisation, interféron, maladie bactérienne, http://aims.fao.org/aos/agrovoc/c_4795, http://aims.fao.org/aos/agrovoc/c_34694, http://aims.fao.org/aos/agrovoc/c_3803, http://aims.fao.org/aos/agrovoc/c_3914, http://aims.fao.org/aos/agrovoc/c_770, |
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dig-cirad-fr-3897442024-01-27T23:02:58Z http://agritrop.cirad.fr/389744/ http://agritrop.cirad.fr/389744/ Protection against Cowdria ruminantium infection in mice with gamma interferon produced in animal cells. Totté Philippe, Vachiery Nathalie, Heremans H., Billiau A., Wérenne John. 1994. In : Animal cell technology: basic and applied aspects = [Technologie de la cellule animale : aspects de niveau simple et appliqué]. Kobayashi T. (ed.). Dordrecht : Kluwer Academic Publishers, 595-599. Protection against Cowdria ruminantium infection in mice with gamma interferon produced in animal cells Totté, Philippe Vachiery, Nathalie Heremans, H. Billiau, A. Wérenne, John eng 1994 Kluwer Academic Publishers Animal cell technology: basic and applied aspects = [Technologie de la cellule animale : aspects de niveau simple et appliqué] L73 - Maladies des animaux souris Ehrlichia ruminantium immunisation interféron maladie bactérienne http://aims.fao.org/aos/agrovoc/c_4795 http://aims.fao.org/aos/agrovoc/c_34694 http://aims.fao.org/aos/agrovoc/c_3803 http://aims.fao.org/aos/agrovoc/c_3914 http://aims.fao.org/aos/agrovoc/c_770 We report here that y interferon produced in animal cell culture injected intraperitoneally, efficiently protects mice against Cow£iria ruminantium infection. None of the other cytokines tested exerted any effect. Neutralizing antibodies against the cytokines (anti IL6, anti TNF, anti yIFN), did not modify the course of the disease, indicating that these cytokines do not play any crucial role in the pathology. The results conceming the protective effect of interferon pave the way towards the establishment of a rational selection method for protective antigens. book_section info:eu-repo/semantics/bookPart Chapter info:eu-repo/semantics/closedAccess http://catalogue-bibliotheques.cirad.fr/cgi-bin/koha/opac-detail.pl?biblionumber=89584 |
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L73 - Maladies des animaux souris Ehrlichia ruminantium immunisation interféron maladie bactérienne http://aims.fao.org/aos/agrovoc/c_4795 http://aims.fao.org/aos/agrovoc/c_34694 http://aims.fao.org/aos/agrovoc/c_3803 http://aims.fao.org/aos/agrovoc/c_3914 http://aims.fao.org/aos/agrovoc/c_770 L73 - Maladies des animaux souris Ehrlichia ruminantium immunisation interféron maladie bactérienne http://aims.fao.org/aos/agrovoc/c_4795 http://aims.fao.org/aos/agrovoc/c_34694 http://aims.fao.org/aos/agrovoc/c_3803 http://aims.fao.org/aos/agrovoc/c_3914 http://aims.fao.org/aos/agrovoc/c_770 |
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L73 - Maladies des animaux souris Ehrlichia ruminantium immunisation interféron maladie bactérienne http://aims.fao.org/aos/agrovoc/c_4795 http://aims.fao.org/aos/agrovoc/c_34694 http://aims.fao.org/aos/agrovoc/c_3803 http://aims.fao.org/aos/agrovoc/c_3914 http://aims.fao.org/aos/agrovoc/c_770 L73 - Maladies des animaux souris Ehrlichia ruminantium immunisation interféron maladie bactérienne http://aims.fao.org/aos/agrovoc/c_4795 http://aims.fao.org/aos/agrovoc/c_34694 http://aims.fao.org/aos/agrovoc/c_3803 http://aims.fao.org/aos/agrovoc/c_3914 http://aims.fao.org/aos/agrovoc/c_770 Totté, Philippe Vachiery, Nathalie Heremans, H. Billiau, A. Wérenne, John Protection against Cowdria ruminantium infection in mice with gamma interferon produced in animal cells |
description |
We report here that y interferon produced in animal cell culture injected intraperitoneally, efficiently protects mice against Cow£iria ruminantium infection. None of the other cytokines tested exerted any effect. Neutralizing antibodies against the cytokines (anti IL6, anti TNF, anti yIFN), did not modify the course of the disease, indicating that these cytokines do not play any crucial role in the pathology. The results conceming the protective effect of interferon pave the way towards the establishment of a rational selection method for protective antigens. |
format |
book_section |
topic_facet |
L73 - Maladies des animaux souris Ehrlichia ruminantium immunisation interféron maladie bactérienne http://aims.fao.org/aos/agrovoc/c_4795 http://aims.fao.org/aos/agrovoc/c_34694 http://aims.fao.org/aos/agrovoc/c_3803 http://aims.fao.org/aos/agrovoc/c_3914 http://aims.fao.org/aos/agrovoc/c_770 |
author |
Totté, Philippe Vachiery, Nathalie Heremans, H. Billiau, A. Wérenne, John |
author_facet |
Totté, Philippe Vachiery, Nathalie Heremans, H. Billiau, A. Wérenne, John |
author_sort |
Totté, Philippe |
title |
Protection against Cowdria ruminantium infection in mice with gamma interferon produced in animal cells |
title_short |
Protection against Cowdria ruminantium infection in mice with gamma interferon produced in animal cells |
title_full |
Protection against Cowdria ruminantium infection in mice with gamma interferon produced in animal cells |
title_fullStr |
Protection against Cowdria ruminantium infection in mice with gamma interferon produced in animal cells |
title_full_unstemmed |
Protection against Cowdria ruminantium infection in mice with gamma interferon produced in animal cells |
title_sort |
protection against cowdria ruminantium infection in mice with gamma interferon produced in animal cells |
publisher |
Kluwer Academic Publishers |
url |
http://agritrop.cirad.fr/389744/ |
work_keys_str_mv |
AT tottephilippe protectionagainstcowdriaruminantiuminfectioninmicewithgammainterferonproducedinanimalcells AT vachierynathalie protectionagainstcowdriaruminantiuminfectioninmicewithgammainterferonproducedinanimalcells AT heremansh protectionagainstcowdriaruminantiuminfectioninmicewithgammainterferonproducedinanimalcells AT billiaua protectionagainstcowdriaruminantiuminfectioninmicewithgammainterferonproducedinanimalcells AT werennejohn protectionagainstcowdriaruminantiuminfectioninmicewithgammainterferonproducedinanimalcells |
_version_ |
1792491223946100736 |