Resistance to diminazene aceturate and isometamidium chloride in South American T. vivax and T. evansi: consequences on treatment and chemoprophylaxis
Little information is available on the sensitivity of Latin American isolates livestock of trypanosomes to trypanocides. Resistance to diminazene aceturate and isometamidium chloride was evaluated in sheep and calves for 3 isolates of #T.vivax# from French Guyana, 1 from Venezuela and 1 isolate of #T. evansi# from Venezuela. Whichever treatment was applied, parasites were no longer detectable the day after the treatment. All the isolates were resistant to diminazene at the dose of 7mg/Kg except one isolate from French Guyana; relapses were recorded 12 to 150 days after the treatments. Sheep were shown to be potentially healthy carriers of #T. vivax# and #T. evansi#. Resistance was not recorded to the treatment with 0,5 mg/Kg isometamidium chloride in #T. Vivax# infected sheep; duration of the protection was evaluated in some of the animals by re-inoculation of the same isolates after every 15 days; the animals protected for more than 4.5 monthes. In #T. evansi# infections, although the infections could not be ascertained, either by direct examination of by mice inoculations, the antibody level appredated by indirect-ELISA #T. evansi# had not decrease 4 monthes after the treatment; it is suggested that this isolate of #T.evansi# is resistant to isometamidium chloride. The use of diminazene aceturate and isometamidium in enzootic and epizootic, monospecific or multispecific situations is discussed, and is opposed to the strategy generally applied in Africa. The role of reservoir of ruminant and dogs for #T. evansi# and eventually of horses for #T. vivax# is recalled.
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Subjects: | L72 - Organismes nuisibles des animaux, L73 - Maladies des animaux, Trypanosoma vivax, Trypanosoma evansi, antiprotozoaire, résistance aux produits chimiques, chimioprévention, contrôle de maladies, http://aims.fao.org/aos/agrovoc/c_27408, http://aims.fao.org/aos/agrovoc/c_27404, http://aims.fao.org/aos/agrovoc/c_512, http://aims.fao.org/aos/agrovoc/c_5736, http://aims.fao.org/aos/agrovoc/c_1524, http://aims.fao.org/aos/agrovoc/c_2327, http://aims.fao.org/aos/agrovoc/c_7253, |
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dig-cirad-fr-3897252024-01-27T23:02:21Z http://agritrop.cirad.fr/389725/ http://agritrop.cirad.fr/389725/ Resistance to diminazene aceturate and isometamidium chloride in South American T. vivax and T. evansi: consequences on treatment and chemoprophylaxis. Desquesnes Marc, Tresse Laurent. 1999. In : Proceedings of first symposium on new world trypanosomes = [Actes du 1er symposium sur les trypanosomes d'Amérique]. Vokaty S. (ed.), Desquesnes M. (ed.). Bridgetown : IICA, 128-138. Symposium on New World Trypanosomes. 1, Georgetown, Guyana, 20 Novembre 1996/22 Novembre 1996. Resistance to diminazene aceturate and isometamidium chloride in South American T. vivax and T. evansi: consequences on treatment and chemoprophylaxis Desquesnes, Marc Tresse, Laurent eng 1999 IICA Proceedings of first symposium on new world trypanosomes = [Actes du 1er symposium sur les trypanosomes d'Amérique] L72 - Organismes nuisibles des animaux L73 - Maladies des animaux Trypanosoma vivax Trypanosoma evansi antiprotozoaire résistance aux produits chimiques chimioprévention contrôle de maladies http://aims.fao.org/aos/agrovoc/c_27408 http://aims.fao.org/aos/agrovoc/c_27404 http://aims.fao.org/aos/agrovoc/c_512 http://aims.fao.org/aos/agrovoc/c_5736 http://aims.fao.org/aos/agrovoc/c_1524 http://aims.fao.org/aos/agrovoc/c_2327 Amérique du Sud http://aims.fao.org/aos/agrovoc/c_7253 Little information is available on the sensitivity of Latin American isolates livestock of trypanosomes to trypanocides. Resistance to diminazene aceturate and isometamidium chloride was evaluated in sheep and calves for 3 isolates of #T.vivax# from French Guyana, 1 from Venezuela and 1 isolate of #T. evansi# from Venezuela. Whichever treatment was applied, parasites were no longer detectable the day after the treatment. All the isolates were resistant to diminazene at the dose of 7mg/Kg except one isolate from French Guyana; relapses were recorded 12 to 150 days after the treatments. Sheep were shown to be potentially healthy carriers of #T. vivax# and #T. evansi#. Resistance was not recorded to the treatment with 0,5 mg/Kg isometamidium chloride in #T. Vivax# infected sheep; duration of the protection was evaluated in some of the animals by re-inoculation of the same isolates after every 15 days; the animals protected for more than 4.5 monthes. In #T. evansi# infections, although the infections could not be ascertained, either by direct examination of by mice inoculations, the antibody level appredated by indirect-ELISA #T. evansi# had not decrease 4 monthes after the treatment; it is suggested that this isolate of #T.evansi# is resistant to isometamidium chloride. The use of diminazene aceturate and isometamidium in enzootic and epizootic, monospecific or multispecific situations is discussed, and is opposed to the strategy generally applied in Africa. The role of reservoir of ruminant and dogs for #T. evansi# and eventually of horses for #T. vivax# is recalled. conference_item info:eu-repo/semantics/conferenceObject Conference info:eu-repo/semantics/closedAccess http://catalogue-bibliotheques.cirad.fr/cgi-bin/koha/opac-detail.pl?biblionumber=89657 |
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L72 - Organismes nuisibles des animaux L73 - Maladies des animaux Trypanosoma vivax Trypanosoma evansi antiprotozoaire résistance aux produits chimiques chimioprévention contrôle de maladies http://aims.fao.org/aos/agrovoc/c_27408 http://aims.fao.org/aos/agrovoc/c_27404 http://aims.fao.org/aos/agrovoc/c_512 http://aims.fao.org/aos/agrovoc/c_5736 http://aims.fao.org/aos/agrovoc/c_1524 http://aims.fao.org/aos/agrovoc/c_2327 http://aims.fao.org/aos/agrovoc/c_7253 L72 - Organismes nuisibles des animaux L73 - Maladies des animaux Trypanosoma vivax Trypanosoma evansi antiprotozoaire résistance aux produits chimiques chimioprévention contrôle de maladies http://aims.fao.org/aos/agrovoc/c_27408 http://aims.fao.org/aos/agrovoc/c_27404 http://aims.fao.org/aos/agrovoc/c_512 http://aims.fao.org/aos/agrovoc/c_5736 http://aims.fao.org/aos/agrovoc/c_1524 http://aims.fao.org/aos/agrovoc/c_2327 http://aims.fao.org/aos/agrovoc/c_7253 |
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L72 - Organismes nuisibles des animaux L73 - Maladies des animaux Trypanosoma vivax Trypanosoma evansi antiprotozoaire résistance aux produits chimiques chimioprévention contrôle de maladies http://aims.fao.org/aos/agrovoc/c_27408 http://aims.fao.org/aos/agrovoc/c_27404 http://aims.fao.org/aos/agrovoc/c_512 http://aims.fao.org/aos/agrovoc/c_5736 http://aims.fao.org/aos/agrovoc/c_1524 http://aims.fao.org/aos/agrovoc/c_2327 http://aims.fao.org/aos/agrovoc/c_7253 L72 - Organismes nuisibles des animaux L73 - Maladies des animaux Trypanosoma vivax Trypanosoma evansi antiprotozoaire résistance aux produits chimiques chimioprévention contrôle de maladies http://aims.fao.org/aos/agrovoc/c_27408 http://aims.fao.org/aos/agrovoc/c_27404 http://aims.fao.org/aos/agrovoc/c_512 http://aims.fao.org/aos/agrovoc/c_5736 http://aims.fao.org/aos/agrovoc/c_1524 http://aims.fao.org/aos/agrovoc/c_2327 http://aims.fao.org/aos/agrovoc/c_7253 Desquesnes, Marc Tresse, Laurent Resistance to diminazene aceturate and isometamidium chloride in South American T. vivax and T. evansi: consequences on treatment and chemoprophylaxis |
description |
Little information is available on the sensitivity of Latin American isolates livestock of trypanosomes to trypanocides. Resistance to diminazene aceturate and isometamidium chloride was evaluated in sheep and calves for 3 isolates of #T.vivax# from French Guyana, 1 from Venezuela and 1 isolate of #T. evansi# from Venezuela. Whichever treatment was applied, parasites were no longer detectable the day after the treatment. All the isolates were resistant to diminazene at the dose of 7mg/Kg except one isolate from French Guyana; relapses were recorded 12 to 150 days after the treatments. Sheep were shown to be potentially healthy carriers of #T. vivax# and #T. evansi#. Resistance was not recorded to the treatment with 0,5 mg/Kg isometamidium chloride in #T. Vivax# infected sheep; duration of the protection was evaluated in some of the animals by re-inoculation of the same isolates after every 15 days; the animals protected for more than 4.5 monthes. In #T. evansi# infections, although the infections could not be ascertained, either by direct examination of by mice inoculations, the antibody level appredated by indirect-ELISA #T. evansi# had not decrease 4 monthes after the treatment; it is suggested that this isolate of #T.evansi# is resistant to isometamidium chloride. The use of diminazene aceturate and isometamidium in enzootic and epizootic, monospecific or multispecific situations is discussed, and is opposed to the strategy generally applied in Africa. The role of reservoir of ruminant and dogs for #T. evansi# and eventually of horses for #T. vivax# is recalled. |
format |
conference_item |
topic_facet |
L72 - Organismes nuisibles des animaux L73 - Maladies des animaux Trypanosoma vivax Trypanosoma evansi antiprotozoaire résistance aux produits chimiques chimioprévention contrôle de maladies http://aims.fao.org/aos/agrovoc/c_27408 http://aims.fao.org/aos/agrovoc/c_27404 http://aims.fao.org/aos/agrovoc/c_512 http://aims.fao.org/aos/agrovoc/c_5736 http://aims.fao.org/aos/agrovoc/c_1524 http://aims.fao.org/aos/agrovoc/c_2327 http://aims.fao.org/aos/agrovoc/c_7253 |
author |
Desquesnes, Marc Tresse, Laurent |
author_facet |
Desquesnes, Marc Tresse, Laurent |
author_sort |
Desquesnes, Marc |
title |
Resistance to diminazene aceturate and isometamidium chloride in South American T. vivax and T. evansi: consequences on treatment and chemoprophylaxis |
title_short |
Resistance to diminazene aceturate and isometamidium chloride in South American T. vivax and T. evansi: consequences on treatment and chemoprophylaxis |
title_full |
Resistance to diminazene aceturate and isometamidium chloride in South American T. vivax and T. evansi: consequences on treatment and chemoprophylaxis |
title_fullStr |
Resistance to diminazene aceturate and isometamidium chloride in South American T. vivax and T. evansi: consequences on treatment and chemoprophylaxis |
title_full_unstemmed |
Resistance to diminazene aceturate and isometamidium chloride in South American T. vivax and T. evansi: consequences on treatment and chemoprophylaxis |
title_sort |
resistance to diminazene aceturate and isometamidium chloride in south american t. vivax and t. evansi: consequences on treatment and chemoprophylaxis |
publisher |
IICA |
url |
http://agritrop.cirad.fr/389725/ |
work_keys_str_mv |
AT desquesnesmarc resistancetodiminazeneaceturateandisometamidiumchlorideinsouthamericantvivaxandtevansiconsequencesontreatmentandchemoprophylaxis AT tresselaurent resistancetodiminazeneaceturateandisometamidiumchlorideinsouthamericantvivaxandtevansiconsequencesontreatmentandchemoprophylaxis |
_version_ |
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