BGGE: a new package for genomic-enabled prediction incorporating genotype × environment interaction models

One of the major issues in plant breeding is the occurrence of genotype × environment (GE) interaction. Several models have been created to understand this phenomenon and explore it. In the genomic era, several models were employed to improve selection by using markers and account for GE interaction simultaneously. Some of these models use special genetic covariance matrices. In addition, the scale of multi-environment trials is getting larger, and this increases the computational challenges. In this context, we propose an R package that, in general, allows building GE genomic covariance matrices and fitting linear mixed models, in particular, to a few genomic GE models. Here we propose two functions: one to prepare the genomic kernels accounting for the genomic GE and another to perform genomic prediction using a Bayesian linear mixed model. A specific treatment is given for sparse covariance matrices, in particular, to block diagonal matrices that are present in some GE models in order to decrease the computational demand. In empirical comparisons with Bayesian Genomic Linear Regression (BGLR), accuracies and the mean squared error were similar; however, the computational time was up to five times lower than when using the classic approach. Bayesian Genomic Genotype × Environment Interaction (BGGE) is a fast, efficient option for creating genomic GE kernels and making genomic predictions.

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Main Authors: Granato, I., Cuevas, J., Luna-Vazquez, F.J., Crossa, J., Montesinos-Lopez, O.A., Burgueño, J., Fritsche-Neto, R.
Format: Article biblioteca
Language:English
Published: Genetics Society of America 2018
Subjects:AGRICULTURAL SCIENCES AND BIOTECHNOLOGY, BGGE, Genomic Selection, Bayesian Genomic Linear Regression, GenPred, Shared Data Resources, BGLR, BAYESIAN THEORY, GENOMICS, SELECTION, REGRESSION ANALYSIS, GENOTYPE ENVIRONMENT INTERACTION,
Online Access:https://hdl.handle.net/10883/19625
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spelling dig-cimmyt-10883-196252021-02-09T18:24:50Z BGGE: a new package for genomic-enabled prediction incorporating genotype × environment interaction models Granato, I. Cuevas, J. Luna-Vazquez, F.J. Crossa, J. Montesinos-Lopez, O.A. Burgueño, J. Fritsche-Neto, R. AGRICULTURAL SCIENCES AND BIOTECHNOLOGY BGGE Genomic Selection Bayesian Genomic Linear Regression GenPred Shared Data Resources BGLR BAYESIAN THEORY GENOMICS SELECTION REGRESSION ANALYSIS GENOTYPE ENVIRONMENT INTERACTION One of the major issues in plant breeding is the occurrence of genotype × environment (GE) interaction. Several models have been created to understand this phenomenon and explore it. In the genomic era, several models were employed to improve selection by using markers and account for GE interaction simultaneously. Some of these models use special genetic covariance matrices. In addition, the scale of multi-environment trials is getting larger, and this increases the computational challenges. In this context, we propose an R package that, in general, allows building GE genomic covariance matrices and fitting linear mixed models, in particular, to a few genomic GE models. Here we propose two functions: one to prepare the genomic kernels accounting for the genomic GE and another to perform genomic prediction using a Bayesian linear mixed model. A specific treatment is given for sparse covariance matrices, in particular, to block diagonal matrices that are present in some GE models in order to decrease the computational demand. In empirical comparisons with Bayesian Genomic Linear Regression (BGLR), accuracies and the mean squared error were similar; however, the computational time was up to five times lower than when using the classic approach. Bayesian Genomic Genotype × Environment Interaction (BGGE) is a fast, efficient option for creating genomic GE kernels and making genomic predictions. 3039-3047 2018-10-02T17:41:57Z 2018-10-02T17:41:57Z 2018 Article 2160-1836 https://hdl.handle.net/10883/19625 10.1534/g3.118.200435 English https://hdl.handle.net/11529/10548107 CIMMYT manages Intellectual Assets as International Public Goods. The user is free to download, print, store and share this work. In case you want to translate or create any other derivative work and share or distribute such translation/derivative work, please contact CIMMYT-Knowledge-Center@cgiar.org indicating the work you want to use and the kind of use you intend; CIMMYT will contact you with the suitable license for that purpose. Open Access PDF Bethesda, Md., U.S. Genetics Society of America 9 8 G3: Genes, Genomes, Genetics
institution CIMMYT
collection DSpace
country México
countrycode MX
component Bibliográfico
access En linea
databasecode dig-cimmyt
tag biblioteca
region America del Norte
libraryname CIMMYT Library
language English
topic AGRICULTURAL SCIENCES AND BIOTECHNOLOGY
BGGE
Genomic Selection
Bayesian Genomic Linear Regression
GenPred
Shared Data Resources
BGLR
BAYESIAN THEORY
GENOMICS
SELECTION
REGRESSION ANALYSIS
GENOTYPE ENVIRONMENT INTERACTION
AGRICULTURAL SCIENCES AND BIOTECHNOLOGY
BGGE
Genomic Selection
Bayesian Genomic Linear Regression
GenPred
Shared Data Resources
BGLR
BAYESIAN THEORY
GENOMICS
SELECTION
REGRESSION ANALYSIS
GENOTYPE ENVIRONMENT INTERACTION
spellingShingle AGRICULTURAL SCIENCES AND BIOTECHNOLOGY
BGGE
Genomic Selection
Bayesian Genomic Linear Regression
GenPred
Shared Data Resources
BGLR
BAYESIAN THEORY
GENOMICS
SELECTION
REGRESSION ANALYSIS
GENOTYPE ENVIRONMENT INTERACTION
AGRICULTURAL SCIENCES AND BIOTECHNOLOGY
BGGE
Genomic Selection
Bayesian Genomic Linear Regression
GenPred
Shared Data Resources
BGLR
BAYESIAN THEORY
GENOMICS
SELECTION
REGRESSION ANALYSIS
GENOTYPE ENVIRONMENT INTERACTION
Granato, I.
Cuevas, J.
Luna-Vazquez, F.J.
Crossa, J.
Montesinos-Lopez, O.A.
Burgueño, J.
Fritsche-Neto, R.
BGGE: a new package for genomic-enabled prediction incorporating genotype × environment interaction models
description One of the major issues in plant breeding is the occurrence of genotype × environment (GE) interaction. Several models have been created to understand this phenomenon and explore it. In the genomic era, several models were employed to improve selection by using markers and account for GE interaction simultaneously. Some of these models use special genetic covariance matrices. In addition, the scale of multi-environment trials is getting larger, and this increases the computational challenges. In this context, we propose an R package that, in general, allows building GE genomic covariance matrices and fitting linear mixed models, in particular, to a few genomic GE models. Here we propose two functions: one to prepare the genomic kernels accounting for the genomic GE and another to perform genomic prediction using a Bayesian linear mixed model. A specific treatment is given for sparse covariance matrices, in particular, to block diagonal matrices that are present in some GE models in order to decrease the computational demand. In empirical comparisons with Bayesian Genomic Linear Regression (BGLR), accuracies and the mean squared error were similar; however, the computational time was up to five times lower than when using the classic approach. Bayesian Genomic Genotype × Environment Interaction (BGGE) is a fast, efficient option for creating genomic GE kernels and making genomic predictions.
format Article
topic_facet AGRICULTURAL SCIENCES AND BIOTECHNOLOGY
BGGE
Genomic Selection
Bayesian Genomic Linear Regression
GenPred
Shared Data Resources
BGLR
BAYESIAN THEORY
GENOMICS
SELECTION
REGRESSION ANALYSIS
GENOTYPE ENVIRONMENT INTERACTION
author Granato, I.
Cuevas, J.
Luna-Vazquez, F.J.
Crossa, J.
Montesinos-Lopez, O.A.
Burgueño, J.
Fritsche-Neto, R.
author_facet Granato, I.
Cuevas, J.
Luna-Vazquez, F.J.
Crossa, J.
Montesinos-Lopez, O.A.
Burgueño, J.
Fritsche-Neto, R.
author_sort Granato, I.
title BGGE: a new package for genomic-enabled prediction incorporating genotype × environment interaction models
title_short BGGE: a new package for genomic-enabled prediction incorporating genotype × environment interaction models
title_full BGGE: a new package for genomic-enabled prediction incorporating genotype × environment interaction models
title_fullStr BGGE: a new package for genomic-enabled prediction incorporating genotype × environment interaction models
title_full_unstemmed BGGE: a new package for genomic-enabled prediction incorporating genotype × environment interaction models
title_sort bgge: a new package for genomic-enabled prediction incorporating genotype × environment interaction models
publisher Genetics Society of America
publishDate 2018
url https://hdl.handle.net/10883/19625
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