Determination of Perfluorooctanoic Acid (PFOA) in the Indoor Dust Matter of the Sicily (Italy) Area: Analysis and Exposure Evaluations
Perfluorooctanoic acid (PFOA) in environmental matrices is increasingly being studied due to its environmental persistence, global occurrence, bioaccumulation, and associated human health risks. Some indoor environments can significantly impact the health of occupants due to pollutants in indoor air and household dust. To investigate the potential exposure of individuals to PFOA in specific confined environments, this study reports an analytical method and results concerning the determination of PFOA in household dust, used as a passive sampler. To the best of our knowledge, this paper represents one of the first studies concerning PFOA concentrations in indoor dust collected in the south of Italy, within the European region. A total of twenty-three dust samples were collected from two different areas of Sicily (Palermo and Milena), extracted, and analyzed by an UHPLC-QTOF-MS/MS system. Finally, PFOA exposure was estimated using a new index (Indoor PFOA Exposure Index, IPEX) that incorporates the PFOA levels in dust, exposure time, and the correlation between the PFOA in dust and blood. It was then compared across four different exposure groups, revealing that PFOA exposure for people working in chemistry laboratories was evaluated to be ten times higher than the exposure for homemakers.
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Multidisciplinary Digital Publishing Institute
2024
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Subjects: | UHPLC-QTOF-MS/MS, PFOA quantification, Indoor dust analysis, PFOA Exposure Index, |
Online Access: | http://hdl.handle.net/10261/362409 |
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dig-cide-es-10261-3624092024-07-04T01:45:35Z Determination of Perfluorooctanoic Acid (PFOA) in the Indoor Dust Matter of the Sicily (Italy) Area: Analysis and Exposure Evaluations Barreca, Salvatore Mizio Mancuso, Michele Marco Sacristán Moraga, Daniel Pace, Andrea Savoca, Darío Orecchio, Santino Consejo Superior de Investigaciones Científicas [https://ror.org/02gfc7t72] UHPLC-QTOF-MS/MS PFOA quantification Indoor dust analysis PFOA Exposure Index Perfluorooctanoic acid (PFOA) in environmental matrices is increasingly being studied due to its environmental persistence, global occurrence, bioaccumulation, and associated human health risks. Some indoor environments can significantly impact the health of occupants due to pollutants in indoor air and household dust. To investigate the potential exposure of individuals to PFOA in specific confined environments, this study reports an analytical method and results concerning the determination of PFOA in household dust, used as a passive sampler. To the best of our knowledge, this paper represents one of the first studies concerning PFOA concentrations in indoor dust collected in the south of Italy, within the European region. A total of twenty-three dust samples were collected from two different areas of Sicily (Palermo and Milena), extracted, and analyzed by an UHPLC-QTOF-MS/MS system. Finally, PFOA exposure was estimated using a new index (Indoor PFOA Exposure Index, IPEX) that incorporates the PFOA levels in dust, exposure time, and the correlation between the PFOA in dust and blood. It was then compared across four different exposure groups, revealing that PFOA exposure for people working in chemistry laboratories was evaluated to be ten times higher than the exposure for homemakers. Peer reviewed 2024-07-02T10:22:29Z 2024-07-02T10:22:29Z 2024 artículo http://purl.org/coar/resource_type/c_6501 Toxics 12(1): 28 (2024) http://hdl.handle.net/10261/362409 10.3390/toxics12010028 2305-6304 en Publisher's version https://doi.org/10.3390/toxics12010028 Sí open application/pdf Multidisciplinary Digital Publishing Institute |
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UHPLC-QTOF-MS/MS PFOA quantification Indoor dust analysis PFOA Exposure Index UHPLC-QTOF-MS/MS PFOA quantification Indoor dust analysis PFOA Exposure Index |
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UHPLC-QTOF-MS/MS PFOA quantification Indoor dust analysis PFOA Exposure Index UHPLC-QTOF-MS/MS PFOA quantification Indoor dust analysis PFOA Exposure Index Barreca, Salvatore Mizio Mancuso, Michele Marco Sacristán Moraga, Daniel Pace, Andrea Savoca, Darío Orecchio, Santino Determination of Perfluorooctanoic Acid (PFOA) in the Indoor Dust Matter of the Sicily (Italy) Area: Analysis and Exposure Evaluations |
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Perfluorooctanoic acid (PFOA) in environmental matrices is increasingly being studied due to its environmental persistence, global occurrence, bioaccumulation, and associated human health risks. Some indoor environments can significantly impact the health of occupants due to pollutants in indoor air and household dust. To investigate the potential exposure of individuals to PFOA in specific confined environments, this study reports an analytical method and results concerning the determination of PFOA in household dust, used as a passive sampler. To the best of our knowledge, this paper represents one of the first studies concerning PFOA concentrations in indoor dust collected in the south of Italy, within the European region. A total of twenty-three dust samples were collected from two different areas of Sicily (Palermo and Milena), extracted, and analyzed by an UHPLC-QTOF-MS/MS system. Finally, PFOA exposure was estimated using a new index (Indoor PFOA Exposure Index, IPEX) that incorporates the PFOA levels in dust, exposure time, and the correlation between the PFOA in dust and blood. It was then compared across four different exposure groups, revealing that PFOA exposure for people working in chemistry laboratories was evaluated to be ten times higher than the exposure for homemakers. |
author2 |
Consejo Superior de Investigaciones Científicas [https://ror.org/02gfc7t72] |
author_facet |
Consejo Superior de Investigaciones Científicas [https://ror.org/02gfc7t72] Barreca, Salvatore Mizio Mancuso, Michele Marco Sacristán Moraga, Daniel Pace, Andrea Savoca, Darío Orecchio, Santino |
format |
artículo |
topic_facet |
UHPLC-QTOF-MS/MS PFOA quantification Indoor dust analysis PFOA Exposure Index |
author |
Barreca, Salvatore Mizio Mancuso, Michele Marco Sacristán Moraga, Daniel Pace, Andrea Savoca, Darío Orecchio, Santino |
author_sort |
Barreca, Salvatore |
title |
Determination of Perfluorooctanoic Acid (PFOA) in the Indoor Dust Matter of the Sicily (Italy) Area: Analysis and Exposure Evaluations |
title_short |
Determination of Perfluorooctanoic Acid (PFOA) in the Indoor Dust Matter of the Sicily (Italy) Area: Analysis and Exposure Evaluations |
title_full |
Determination of Perfluorooctanoic Acid (PFOA) in the Indoor Dust Matter of the Sicily (Italy) Area: Analysis and Exposure Evaluations |
title_fullStr |
Determination of Perfluorooctanoic Acid (PFOA) in the Indoor Dust Matter of the Sicily (Italy) Area: Analysis and Exposure Evaluations |
title_full_unstemmed |
Determination of Perfluorooctanoic Acid (PFOA) in the Indoor Dust Matter of the Sicily (Italy) Area: Analysis and Exposure Evaluations |
title_sort |
determination of perfluorooctanoic acid (pfoa) in the indoor dust matter of the sicily (italy) area: analysis and exposure evaluations |
publisher |
Multidisciplinary Digital Publishing Institute |
publishDate |
2024 |
url |
http://hdl.handle.net/10261/362409 |
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