Effect of methylparaben in Artemia franciscana
In this study, the toxicity of methylparaben (MeP) an emerging contaminant, was analysed in the sexual species Artemia franciscana, due to its presence in coastal areas and marine saltworks in the Mediterranean region. The acute toxicity (24 h-LC50) of MeP in nauplii was tested and its chronic effect (9 days) evaluated by measuring survival and growth under two sublethal concentrations (0.0085 and 0.017 mg/L). Also, the effect on several key enzymes involved in: antioxidant defences (catalase (CAT) and gluthathion-S-transferase (GST)), neural activity (cholinesterase (ChE)) and xenobiotic biotransformation (carboxylesterase (CbE), was assessed after 48 h under sublethal exposure. The results of acute exposure indicate that MeP is harmful to A. franciscana (24 h-LC50 = 36.7 mg/L). MeP causes a decrease in CAT activity after 48 h exposure to both concentration tested, that points out at the oxidative stress effect of MeP in A. franciscana. However, no significant effect on ChE, CbE and GST activities was found. In addition, MeP does not affect survival and growth in chronic exposure at the sublethal concentrations tested. The results of this study indicate that MeP is not a threat for A. franciscana under the experimental conditions used. Additional studies should be done considering long-term exposure and reproduction studies to analyse the potential risk of MeP as emerging contaminant in marine and hypersaline environments.
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Language: | English |
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Elsevier
2017-09
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Subjects: | Methylparaben, Artemia franciscana, Toxicity, Biomarkers, Biodiversity, Aquaculture, |
Online Access: | http://hdl.handle.net/10261/190022 http://dx.doi.org/10.13039/501100003359 |
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dig-cide-es-10261-1900222022-10-04T07:54:42Z Effect of methylparaben in Artemia franciscana Comeche Sanz, Amparo Martín-Villamil, M. Picó, Yolanda Varó, Inmaculada Generalitat Valenciana Picó, Yolanda [0000-0002-9545-0965] Varó, Inmaculada [0000-0002-3937-3846] Methylparaben Artemia franciscana Toxicity Biomarkers Biodiversity Aquaculture In this study, the toxicity of methylparaben (MeP) an emerging contaminant, was analysed in the sexual species Artemia franciscana, due to its presence in coastal areas and marine saltworks in the Mediterranean region. The acute toxicity (24 h-LC50) of MeP in nauplii was tested and its chronic effect (9 days) evaluated by measuring survival and growth under two sublethal concentrations (0.0085 and 0.017 mg/L). Also, the effect on several key enzymes involved in: antioxidant defences (catalase (CAT) and gluthathion-S-transferase (GST)), neural activity (cholinesterase (ChE)) and xenobiotic biotransformation (carboxylesterase (CbE), was assessed after 48 h under sublethal exposure. The results of acute exposure indicate that MeP is harmful to A. franciscana (24 h-LC50 = 36.7 mg/L). MeP causes a decrease in CAT activity after 48 h exposure to both concentration tested, that points out at the oxidative stress effect of MeP in A. franciscana. However, no significant effect on ChE, CbE and GST activities was found. In addition, MeP does not affect survival and growth in chronic exposure at the sublethal concentrations tested. The results of this study indicate that MeP is not a threat for A. franciscana under the experimental conditions used. Additional studies should be done considering long-term exposure and reproduction studies to analyse the potential risk of MeP as emerging contaminant in marine and hypersaline environments. Work financed by Generalitat Valenciana (GV-2014/085-PROMETEO-II), and it has been carried out under the frame-work of the Microcluster “AQUACLUSTER” (CSIC-Universitat de València). Peer reviewed 2019-09-06T07:10:33Z 2019-09-06T07:10:33Z 2017-09 artículo http://purl.org/coar/resource_type/c_6501 Comparative Biochemistry and Physiology - C - Toxicology and Pharmacology 199: 98-105 (2017) 0010-406X http://hdl.handle.net/10261/190022 10.1016/j.cbpc.2017.04.004 http://dx.doi.org/10.13039/501100003359 en http://dx.doi.org/10.1016/j.cbpc.2017.04.004 Sí none Elsevier |
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Methylparaben Artemia franciscana Toxicity Biomarkers Biodiversity Aquaculture Methylparaben Artemia franciscana Toxicity Biomarkers Biodiversity Aquaculture |
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Methylparaben Artemia franciscana Toxicity Biomarkers Biodiversity Aquaculture Methylparaben Artemia franciscana Toxicity Biomarkers Biodiversity Aquaculture Comeche Sanz, Amparo Martín-Villamil, M. Picó, Yolanda Varó, Inmaculada Effect of methylparaben in Artemia franciscana |
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In this study, the toxicity of methylparaben (MeP) an emerging contaminant, was analysed in the sexual species Artemia franciscana, due to its presence in coastal areas and marine saltworks in the Mediterranean region. The acute toxicity (24 h-LC50) of MeP in nauplii was tested and its chronic effect (9 days) evaluated by measuring survival and growth under two sublethal concentrations (0.0085 and 0.017 mg/L). Also, the effect on several key enzymes involved in: antioxidant defences (catalase (CAT) and gluthathion-S-transferase (GST)), neural activity (cholinesterase (ChE)) and xenobiotic biotransformation (carboxylesterase (CbE), was assessed after 48 h under sublethal exposure. The results of acute exposure indicate that MeP is harmful to A. franciscana (24 h-LC50 = 36.7 mg/L). MeP causes a decrease in CAT activity after 48 h exposure to both concentration tested, that points out at the oxidative stress effect of MeP in A. franciscana. However, no significant effect on ChE, CbE and GST activities was found.
In addition, MeP does not affect survival and growth in chronic exposure at the sublethal concentrations tested. The results of this study indicate that MeP is not a threat for A. franciscana under the experimental conditions used. Additional studies should be done considering long-term exposure and reproduction studies to analyse the potential risk of MeP as emerging contaminant in marine and hypersaline environments. |
author2 |
Generalitat Valenciana |
author_facet |
Generalitat Valenciana Comeche Sanz, Amparo Martín-Villamil, M. Picó, Yolanda Varó, Inmaculada |
format |
artículo |
topic_facet |
Methylparaben Artemia franciscana Toxicity Biomarkers Biodiversity Aquaculture |
author |
Comeche Sanz, Amparo Martín-Villamil, M. Picó, Yolanda Varó, Inmaculada |
author_sort |
Comeche Sanz, Amparo |
title |
Effect of methylparaben in Artemia franciscana |
title_short |
Effect of methylparaben in Artemia franciscana |
title_full |
Effect of methylparaben in Artemia franciscana |
title_fullStr |
Effect of methylparaben in Artemia franciscana |
title_full_unstemmed |
Effect of methylparaben in Artemia franciscana |
title_sort |
effect of methylparaben in artemia franciscana |
publisher |
Elsevier |
publishDate |
2017-09 |
url |
http://hdl.handle.net/10261/190022 http://dx.doi.org/10.13039/501100003359 |
work_keys_str_mv |
AT comechesanzamparo effectofmethylparabeninartemiafranciscana AT martinvillamilm effectofmethylparabeninartemiafranciscana AT picoyolanda effectofmethylparabeninartemiafranciscana AT varoinmaculada effectofmethylparabeninartemiafranciscana |
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