Ultra-high-pressure liquid chromatography tandem mass spectrometry method for the determination of 9 organophosphate flame retardants in water samples
Few methods are available for comprehensive organophosphate flame retardants (PFRs) detection in water and wastewater. Gas chromatography has been employed previously, but this approach is less selective, not amenable for use with deuterated standards and can suffer unfavorable fragmentation. Ultra-high-pressure liquid chromatography tandem mass spectrometry (UHPLC-QqQ-MS/MS) has become the most promising platform, already applied successfully for analysis of selected PFRs in some environmental matrices like water and wastewater. However, the presence of some interferences from the dissolvent, the equipment and the used materials should be taken into account. The procedure involves: The first determination of PFRs by UHPLC-QqQ-MS/MS using a trap column to distinguish the interferences coming from the instrument and mobile phases.The optimization of the LC separation to distinguish all target compounds and their interferences.This method coupled to a solid-phase extraction (SPE) improve the detection and quantification of PFRs.
Main Authors: | , , |
---|---|
Other Authors: | |
Format: | artículo biblioteca |
Published: |
Elsevier
2016
|
Subjects: | Interferences, LC–MS/MS, Trap column, Water, Organophosphate flame retardants, solid phase extraction, |
Online Access: | http://hdl.handle.net/10261/141196 http://dx.doi.org/10.13039/501100003329 http://dx.doi.org/10.13039/501100010805 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
id |
dig-cide-es-10261-141196 |
---|---|
record_format |
koha |
spelling |
dig-cide-es-10261-1411962021-12-27T15:54:01Z Ultra-high-pressure liquid chromatography tandem mass spectrometry method for the determination of 9 organophosphate flame retardants in water samples Lorenzo, María Campo, Julián Picó, Yolanda Ministerio de Economía y Competitividad (España) Universidad de Valencia Fundación Tatiana Pérez de Guzmán el Bueno Interferences LC–MS/MS Trap column Water Organophosphate flame retardants solid phase extraction Few methods are available for comprehensive organophosphate flame retardants (PFRs) detection in water and wastewater. Gas chromatography has been employed previously, but this approach is less selective, not amenable for use with deuterated standards and can suffer unfavorable fragmentation. Ultra-high-pressure liquid chromatography tandem mass spectrometry (UHPLC-QqQ-MS/MS) has become the most promising platform, already applied successfully for analysis of selected PFRs in some environmental matrices like water and wastewater. However, the presence of some interferences from the dissolvent, the equipment and the used materials should be taken into account. The procedure involves: The first determination of PFRs by UHPLC-QqQ-MS/MS using a trap column to distinguish the interferences coming from the instrument and mobile phases.The optimization of the LC separation to distinguish all target compounds and their interferences.This method coupled to a solid-phase extraction (SPE) improve the detection and quantification of PFRs. This work has been supported by the Spanish Ministry of Economy and Competitiveness through the projects GCL2011-29703-C02-02 (http://mefturia.es) and GCL2015-64454-C2-1-R (ECO2risk-dds) and the University of Valencia through the project (UV-INV-AE15-348995). María Lorenzo also acknowledges to the Foundation “Tatiana Pérez de Guzmán el Bueno” for the grant to get the PhD. Peer Reviewed 2016-12-07T10:37:54Z 2016-12-07T10:37:54Z 2016 2016-12-07T10:37:55Z artículo http://purl.org/coar/resource_type/c_6501 issn: 2215-0161 MethodsX 3: 343-349 (2016) http://hdl.handle.net/10261/141196 10.1016/j.mex.2016.04.006 http://dx.doi.org/10.13039/501100003329 http://dx.doi.org/10.13039/501100010805 27222824 Postprint https://doi.org/10.1016/j.mex.2016.04.006 Sí open Elsevier |
institution |
CIDE ES |
collection |
DSpace |
country |
España |
countrycode |
ES |
component |
Bibliográfico |
access |
En linea |
databasecode |
dig-cide-es |
tag |
biblioteca |
region |
Europa del Sur |
libraryname |
Biblioteca del CIDE España |
topic |
Interferences LC–MS/MS Trap column Water Organophosphate flame retardants solid phase extraction Interferences LC–MS/MS Trap column Water Organophosphate flame retardants solid phase extraction |
spellingShingle |
Interferences LC–MS/MS Trap column Water Organophosphate flame retardants solid phase extraction Interferences LC–MS/MS Trap column Water Organophosphate flame retardants solid phase extraction Lorenzo, María Campo, Julián Picó, Yolanda Ultra-high-pressure liquid chromatography tandem mass spectrometry method for the determination of 9 organophosphate flame retardants in water samples |
description |
Few methods are available for comprehensive organophosphate flame retardants (PFRs) detection in water and wastewater. Gas chromatography has been employed previously, but this approach is less selective, not amenable for use with deuterated standards and can suffer unfavorable fragmentation. Ultra-high-pressure liquid chromatography tandem mass spectrometry (UHPLC-QqQ-MS/MS) has become the most promising platform, already applied successfully for analysis of selected PFRs in some environmental matrices like water and wastewater. However, the presence of some interferences from the dissolvent, the equipment and the used materials should be taken into account. The procedure involves: The first determination of PFRs by UHPLC-QqQ-MS/MS using a trap column to distinguish the interferences coming from the instrument and mobile phases.The optimization of the LC separation to distinguish all target compounds and their interferences.This method coupled to a solid-phase extraction (SPE) improve the detection and quantification of PFRs. |
author2 |
Ministerio de Economía y Competitividad (España) |
author_facet |
Ministerio de Economía y Competitividad (España) Lorenzo, María Campo, Julián Picó, Yolanda |
format |
artículo |
topic_facet |
Interferences LC–MS/MS Trap column Water Organophosphate flame retardants solid phase extraction |
author |
Lorenzo, María Campo, Julián Picó, Yolanda |
author_sort |
Lorenzo, María |
title |
Ultra-high-pressure liquid chromatography tandem mass spectrometry method for the determination of 9 organophosphate flame retardants in water samples |
title_short |
Ultra-high-pressure liquid chromatography tandem mass spectrometry method for the determination of 9 organophosphate flame retardants in water samples |
title_full |
Ultra-high-pressure liquid chromatography tandem mass spectrometry method for the determination of 9 organophosphate flame retardants in water samples |
title_fullStr |
Ultra-high-pressure liquid chromatography tandem mass spectrometry method for the determination of 9 organophosphate flame retardants in water samples |
title_full_unstemmed |
Ultra-high-pressure liquid chromatography tandem mass spectrometry method for the determination of 9 organophosphate flame retardants in water samples |
title_sort |
ultra-high-pressure liquid chromatography tandem mass spectrometry method for the determination of 9 organophosphate flame retardants in water samples |
publisher |
Elsevier |
publishDate |
2016 |
url |
http://hdl.handle.net/10261/141196 http://dx.doi.org/10.13039/501100003329 http://dx.doi.org/10.13039/501100010805 |
work_keys_str_mv |
AT lorenzomaria ultrahighpressureliquidchromatographytandemmassspectrometrymethodforthedeterminationof9organophosphateflameretardantsinwatersamples AT campojulian ultrahighpressureliquidchromatographytandemmassspectrometrymethodforthedeterminationof9organophosphateflameretardantsinwatersamples AT picoyolanda ultrahighpressureliquidchromatographytandemmassspectrometrymethodforthedeterminationof9organophosphateflameretardantsinwatersamples |
_version_ |
1777665539191078912 |