Mushrooms do not contain flavonoids

A literature and database review and several experiments were carried out because of the perturbing increase and exponential spreading of a major mistake thought scientific publications. Up to October 2015, more than 136 reports ensured that mushrooms contain flavonoids. However, 91% of the publications used an unspecific colorimetric method that was developed to quantify them in plants. However, no sequences encoding chalcone synthase or chalcone isomerase (key enzymes involved in the flavonoid biosynthetic pathway) were found in genomic databases even in completely sequenced mushrooms indicating that they do not have the enzymes needed for their production. Fruiting bodies obtained from substrates containing onion wastes and mycelia grown on media supplemented with specific flavonoids showed no flavonoid content after HPLC DAD/MS determinations indicating that they were also unable of absorbing them.

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Bibliographic Details
Main Authors: Gil-Ramírez, Alicia, Pavo-Caballero, Cristina, Baeza, Esther, Baenas, Nieves, García-Viguera, Cristina, Marin, Francisco R., Soler-Rivas, Cristina
Other Authors: Comunidad de Madrid
Format: artículo biblioteca
Published: Elsevier 2016
Subjects:Phenylalanine ammonia-lyase, Chalcone synthase, Chalcone isomerase, Flavonoids, Mushrooms,
Online Access:http://hdl.handle.net/10261/150532
http://dx.doi.org/10.13039/501100003329
http://dx.doi.org/10.13039/100012818
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spelling dig-cial-es-10261-1505322024-04-30T12:49:40Z Mushrooms do not contain flavonoids Gil-Ramírez, Alicia Pavo-Caballero, Cristina Baeza, Esther Baenas, Nieves García-Viguera, Cristina Marin, Francisco R. Soler-Rivas, Cristina Comunidad de Madrid Ministerio de Economía y Competitividad (España) Phenylalanine ammonia-lyase Chalcone synthase Chalcone isomerase Flavonoids Mushrooms A literature and database review and several experiments were carried out because of the perturbing increase and exponential spreading of a major mistake thought scientific publications. Up to October 2015, more than 136 reports ensured that mushrooms contain flavonoids. However, 91% of the publications used an unspecific colorimetric method that was developed to quantify them in plants. However, no sequences encoding chalcone synthase or chalcone isomerase (key enzymes involved in the flavonoid biosynthetic pathway) were found in genomic databases even in completely sequenced mushrooms indicating that they do not have the enzymes needed for their production. Fruiting bodies obtained from substrates containing onion wastes and mycelia grown on media supplemented with specific flavonoids showed no flavonoid content after HPLC DAD/MS determinations indicating that they were also unable of absorbing them. This review was supported by AGL2010-21537 and AGL2014-56211-R projects financed by the national R + D program from the Spanish Ministry of Science and Innovation and ALIBIRD-C M S2009/AGR-1469 regional program from the Community of Madrid (Spain). Peer Reviewed 2017-05-29T07:26:33Z 2017-05-29T07:26:33Z 2016 2017-05-29T07:26:33Z artículo http://purl.org/coar/resource_type/c_6501 doi: 10.1016/j.jff.2016.05.005 issn: 1756-4646 e-issn: 2214-9414 Journal of Functional Foods 25: 1-13 (2016) http://hdl.handle.net/10261/150532 10.1016/j.jff.2016.05.005 http://dx.doi.org/10.13039/501100003329 http://dx.doi.org/10.13039/100012818 #PLACEHOLDER_PARENT_METADATA_VALUE# #PLACEHOLDER_PARENT_METADATA_VALUE# info:eu-repo/grantAgreement/MINECO/Plan Estatal de Investigación Científica y Técnica y de Innovación 2013-2016/AGL2014-56211-R S2009/AGR-1469/ALIBIRD Postprint https://doi.org/10.1016/j.jff.2016.05.005 Sí open Elsevier
institution CIAL ES
collection DSpace
country España
countrycode ES
component Bibliográfico
access En linea
databasecode dig-cial-es
tag biblioteca
region Europa del Sur
libraryname Biblioteca del CIAL España
topic Phenylalanine ammonia-lyase
Chalcone synthase
Chalcone isomerase
Flavonoids
Mushrooms
Phenylalanine ammonia-lyase
Chalcone synthase
Chalcone isomerase
Flavonoids
Mushrooms
spellingShingle Phenylalanine ammonia-lyase
Chalcone synthase
Chalcone isomerase
Flavonoids
Mushrooms
Phenylalanine ammonia-lyase
Chalcone synthase
Chalcone isomerase
Flavonoids
Mushrooms
Gil-Ramírez, Alicia
Pavo-Caballero, Cristina
Baeza, Esther
Baenas, Nieves
García-Viguera, Cristina
Marin, Francisco R.
Soler-Rivas, Cristina
Mushrooms do not contain flavonoids
description A literature and database review and several experiments were carried out because of the perturbing increase and exponential spreading of a major mistake thought scientific publications. Up to October 2015, more than 136 reports ensured that mushrooms contain flavonoids. However, 91% of the publications used an unspecific colorimetric method that was developed to quantify them in plants. However, no sequences encoding chalcone synthase or chalcone isomerase (key enzymes involved in the flavonoid biosynthetic pathway) were found in genomic databases even in completely sequenced mushrooms indicating that they do not have the enzymes needed for their production. Fruiting bodies obtained from substrates containing onion wastes and mycelia grown on media supplemented with specific flavonoids showed no flavonoid content after HPLC DAD/MS determinations indicating that they were also unable of absorbing them.
author2 Comunidad de Madrid
author_facet Comunidad de Madrid
Gil-Ramírez, Alicia
Pavo-Caballero, Cristina
Baeza, Esther
Baenas, Nieves
García-Viguera, Cristina
Marin, Francisco R.
Soler-Rivas, Cristina
format artículo
topic_facet Phenylalanine ammonia-lyase
Chalcone synthase
Chalcone isomerase
Flavonoids
Mushrooms
author Gil-Ramírez, Alicia
Pavo-Caballero, Cristina
Baeza, Esther
Baenas, Nieves
García-Viguera, Cristina
Marin, Francisco R.
Soler-Rivas, Cristina
author_sort Gil-Ramírez, Alicia
title Mushrooms do not contain flavonoids
title_short Mushrooms do not contain flavonoids
title_full Mushrooms do not contain flavonoids
title_fullStr Mushrooms do not contain flavonoids
title_full_unstemmed Mushrooms do not contain flavonoids
title_sort mushrooms do not contain flavonoids
publisher Elsevier
publishDate 2016
url http://hdl.handle.net/10261/150532
http://dx.doi.org/10.13039/501100003329
http://dx.doi.org/10.13039/100012818
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AT garciavigueracristina mushroomsdonotcontainflavonoids
AT marinfranciscor mushroomsdonotcontainflavonoids
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