Mushrooms do not contain flavonoids
A literature and database review and several experiments were carried out because of the perturbing increase and exponential spreading of a major mistake thought scientific publications. Up to October 2015, more than 136 reports ensured that mushrooms contain flavonoids. However, 91% of the publications used an unspecific colorimetric method that was developed to quantify them in plants. However, no sequences encoding chalcone synthase or chalcone isomerase (key enzymes involved in the flavonoid biosynthetic pathway) were found in genomic databases even in completely sequenced mushrooms indicating that they do not have the enzymes needed for their production. Fruiting bodies obtained from substrates containing onion wastes and mycelia grown on media supplemented with specific flavonoids showed no flavonoid content after HPLC DAD/MS determinations indicating that they were also unable of absorbing them.
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Format: | artículo biblioteca |
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Elsevier
2016
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Subjects: | Phenylalanine ammonia-lyase, Chalcone synthase, Chalcone isomerase, Flavonoids, Mushrooms, |
Online Access: | http://hdl.handle.net/10261/150532 http://dx.doi.org/10.13039/501100003329 http://dx.doi.org/10.13039/100012818 |
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dig-cial-es-10261-1505322024-04-30T12:49:40Z Mushrooms do not contain flavonoids Gil-Ramírez, Alicia Pavo-Caballero, Cristina Baeza, Esther Baenas, Nieves García-Viguera, Cristina Marin, Francisco R. Soler-Rivas, Cristina Comunidad de Madrid Ministerio de Economía y Competitividad (España) Phenylalanine ammonia-lyase Chalcone synthase Chalcone isomerase Flavonoids Mushrooms A literature and database review and several experiments were carried out because of the perturbing increase and exponential spreading of a major mistake thought scientific publications. Up to October 2015, more than 136 reports ensured that mushrooms contain flavonoids. However, 91% of the publications used an unspecific colorimetric method that was developed to quantify them in plants. However, no sequences encoding chalcone synthase or chalcone isomerase (key enzymes involved in the flavonoid biosynthetic pathway) were found in genomic databases even in completely sequenced mushrooms indicating that they do not have the enzymes needed for their production. Fruiting bodies obtained from substrates containing onion wastes and mycelia grown on media supplemented with specific flavonoids showed no flavonoid content after HPLC DAD/MS determinations indicating that they were also unable of absorbing them. This review was supported by AGL2010-21537 and AGL2014-56211-R projects financed by the national R + D program from the Spanish Ministry of Science and Innovation and ALIBIRD-C M S2009/AGR-1469 regional program from the Community of Madrid (Spain). Peer Reviewed 2017-05-29T07:26:33Z 2017-05-29T07:26:33Z 2016 2017-05-29T07:26:33Z artículo http://purl.org/coar/resource_type/c_6501 doi: 10.1016/j.jff.2016.05.005 issn: 1756-4646 e-issn: 2214-9414 Journal of Functional Foods 25: 1-13 (2016) http://hdl.handle.net/10261/150532 10.1016/j.jff.2016.05.005 http://dx.doi.org/10.13039/501100003329 http://dx.doi.org/10.13039/100012818 #PLACEHOLDER_PARENT_METADATA_VALUE# #PLACEHOLDER_PARENT_METADATA_VALUE# info:eu-repo/grantAgreement/MINECO/Plan Estatal de Investigación Científica y Técnica y de Innovación 2013-2016/AGL2014-56211-R S2009/AGR-1469/ALIBIRD Postprint https://doi.org/10.1016/j.jff.2016.05.005 Sí open Elsevier |
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Phenylalanine ammonia-lyase Chalcone synthase Chalcone isomerase Flavonoids Mushrooms Phenylalanine ammonia-lyase Chalcone synthase Chalcone isomerase Flavonoids Mushrooms |
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Phenylalanine ammonia-lyase Chalcone synthase Chalcone isomerase Flavonoids Mushrooms Phenylalanine ammonia-lyase Chalcone synthase Chalcone isomerase Flavonoids Mushrooms Gil-Ramírez, Alicia Pavo-Caballero, Cristina Baeza, Esther Baenas, Nieves García-Viguera, Cristina Marin, Francisco R. Soler-Rivas, Cristina Mushrooms do not contain flavonoids |
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A literature and database review and several experiments were carried out because of the perturbing increase and exponential spreading of a major mistake thought scientific publications. Up to October 2015, more than 136 reports ensured that mushrooms contain flavonoids. However, 91% of the publications used an unspecific colorimetric method that was developed to quantify them in plants. However, no sequences encoding chalcone synthase or chalcone isomerase (key enzymes involved in the flavonoid biosynthetic pathway) were found in genomic databases even in completely sequenced mushrooms indicating that they do not have the enzymes needed for their production. Fruiting bodies obtained from substrates containing onion wastes and mycelia grown on media supplemented with specific flavonoids showed no flavonoid content after HPLC DAD/MS determinations indicating that they were also unable of absorbing them. |
author2 |
Comunidad de Madrid |
author_facet |
Comunidad de Madrid Gil-Ramírez, Alicia Pavo-Caballero, Cristina Baeza, Esther Baenas, Nieves García-Viguera, Cristina Marin, Francisco R. Soler-Rivas, Cristina |
format |
artículo |
topic_facet |
Phenylalanine ammonia-lyase Chalcone synthase Chalcone isomerase Flavonoids Mushrooms |
author |
Gil-Ramírez, Alicia Pavo-Caballero, Cristina Baeza, Esther Baenas, Nieves García-Viguera, Cristina Marin, Francisco R. Soler-Rivas, Cristina |
author_sort |
Gil-Ramírez, Alicia |
title |
Mushrooms do not contain flavonoids |
title_short |
Mushrooms do not contain flavonoids |
title_full |
Mushrooms do not contain flavonoids |
title_fullStr |
Mushrooms do not contain flavonoids |
title_full_unstemmed |
Mushrooms do not contain flavonoids |
title_sort |
mushrooms do not contain flavonoids |
publisher |
Elsevier |
publishDate |
2016 |
url |
http://hdl.handle.net/10261/150532 http://dx.doi.org/10.13039/501100003329 http://dx.doi.org/10.13039/100012818 |
work_keys_str_mv |
AT gilramirezalicia mushroomsdonotcontainflavonoids AT pavocaballerocristina mushroomsdonotcontainflavonoids AT baezaesther mushroomsdonotcontainflavonoids AT baenasnieves mushroomsdonotcontainflavonoids AT garciavigueracristina mushroomsdonotcontainflavonoids AT marinfranciscor mushroomsdonotcontainflavonoids AT solerrivascristina mushroomsdonotcontainflavonoids |
_version_ |
1802820616572633088 |