Cytogenetic Mapping of 35 New Markers in the Alpaca (Vicugna pacos)
Universidad Nacional Agraria La Molina. Escuela de Posgrado. Maestría en Producción Animal
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| Language: | eng |
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MDPI
2020
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| Subjects: | Alpaca, Código genético, Mapas genéticos, Marcadores genéticos, Biotecnología animal, Técnicas analíticas, Evaluación, Perú, https://purl.org/pe-repo/ocde/ford#4.02.01, |
| Online Access: | https://hdl.handle.net/20.500.12996/5012 https://doi.org/10.3390/genes11050522 |
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dig-ban-20.500.12996-50122024-07-09T14:23:07Z Cytogenetic Mapping of 35 New Markers in the Alpaca (Vicugna pacos) Mendoza, Mayra N. Raudsepp, Terje More, Manuel J. Gutiérrez, Gustavo A. Ponce de León, F. Abel Alpaca Código genético Mapas genéticos Marcadores genéticos Biotecnología animal Técnicas analíticas Evaluación Evaluación Perú https://purl.org/pe-repo/ocde/ford#4.02.01 Universidad Nacional Agraria La Molina. Escuela de Posgrado. Maestría en Producción Animal Alpaca is a camelid species of broad economic, biological and biomedical interest, and an essential part of the cultural and historical heritage of Peru. Recently, efforts have been made to improve knowledge of the alpaca genome, and its genetics and cytogenetics, to develop molecular tools for selection and breeding. Here, we report cytogenetic mapping of 35 new markers to 19 alpaca autosomes and the X chromosome. Twenty-eight markers represent alpaca SNPs, of which 17 are located inside or near protein-coding genes, two are in ncRNA genes and nine are intergenic. The remaining seven markers correspond to candidate genes for fiber characteristics (BMP4, COL1A2, GLI1, SFRP4), coat color (TYR) and development (CHD7, PAX7). The results take the tally of cytogenetically mapped markers in alpaca to 281, covering all 36 autosomes and the sex chromosomes. The new map assignments overall agree with human–camelid conserved synteny data, except for mapping BMP4 to VPA3, suggesting a hitherto unknown homology with HSA14. The findings validate, refine and correct the current alpaca assembly VicPac3.1 by anchoring unassigned sequence scaffolds, and ordering and orienting assigned scaffolds. The study contributes to the improvement in the alpaca reference genome and advances camelid molecular cytogenetics. View Full-Text 2021-11-05T19:33:44Z 2021-11-05T19:33:44Z 2020 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Mendoza, Mayra N., Terje Raudsepp, Manuel J. More, Gustavo A. Gutiérrez, and F. A. Ponce de León 2020. "Cytogenetic Mapping of 35 New Markers in the Alpaca (Vicugna pacos)" Genes 11, no. 5: 522. https://doi.org/10.3390/genes11050522 https://hdl.handle.net/20.500.12996/5012 https://doi.org/10.3390/genes11050522 eng info:eu-repo/semantics/openAccess application/pdf application/pdf MDPI CH https://www.mdpi.com/2073-4425/11/5/522 |
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| country |
Perú |
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PE |
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| tag |
biblioteca |
| region |
America del Sur |
| libraryname |
Biblioteca Agrícola Nacional de la Molina |
| language |
eng |
| topic |
Alpaca Código genético Mapas genéticos Marcadores genéticos Biotecnología animal Técnicas analíticas Evaluación Evaluación Perú https://purl.org/pe-repo/ocde/ford#4.02.01 Alpaca Código genético Mapas genéticos Marcadores genéticos Biotecnología animal Técnicas analíticas Evaluación Evaluación Perú https://purl.org/pe-repo/ocde/ford#4.02.01 |
| spellingShingle |
Alpaca Código genético Mapas genéticos Marcadores genéticos Biotecnología animal Técnicas analíticas Evaluación Evaluación Perú https://purl.org/pe-repo/ocde/ford#4.02.01 Alpaca Código genético Mapas genéticos Marcadores genéticos Biotecnología animal Técnicas analíticas Evaluación Evaluación Perú https://purl.org/pe-repo/ocde/ford#4.02.01 Mendoza, Mayra N. Raudsepp, Terje More, Manuel J. Gutiérrez, Gustavo A. Ponce de León, F. Abel Cytogenetic Mapping of 35 New Markers in the Alpaca (Vicugna pacos) |
| description |
Universidad Nacional Agraria La Molina. Escuela de Posgrado. Maestría en Producción Animal |
| format |
info:eu-repo/semantics/article |
| topic_facet |
Alpaca Código genético Mapas genéticos Marcadores genéticos Biotecnología animal Técnicas analíticas Evaluación Evaluación Perú https://purl.org/pe-repo/ocde/ford#4.02.01 |
| author |
Mendoza, Mayra N. Raudsepp, Terje More, Manuel J. Gutiérrez, Gustavo A. Ponce de León, F. Abel |
| author_facet |
Mendoza, Mayra N. Raudsepp, Terje More, Manuel J. Gutiérrez, Gustavo A. Ponce de León, F. Abel |
| author_sort |
Mendoza, Mayra N. |
| title |
Cytogenetic Mapping of 35 New Markers in the Alpaca (Vicugna pacos) |
| title_short |
Cytogenetic Mapping of 35 New Markers in the Alpaca (Vicugna pacos) |
| title_full |
Cytogenetic Mapping of 35 New Markers in the Alpaca (Vicugna pacos) |
| title_fullStr |
Cytogenetic Mapping of 35 New Markers in the Alpaca (Vicugna pacos) |
| title_full_unstemmed |
Cytogenetic Mapping of 35 New Markers in the Alpaca (Vicugna pacos) |
| title_sort |
cytogenetic mapping of 35 new markers in the alpaca (vicugna pacos) |
| publisher |
MDPI |
| publishDate |
2020 |
| url |
https://hdl.handle.net/20.500.12996/5012 https://doi.org/10.3390/genes11050522 |
| work_keys_str_mv |
AT mendozamayran cytogeneticmappingof35newmarkersinthealpacavicugnapacos AT raudseppterje cytogeneticmappingof35newmarkersinthealpacavicugnapacos AT moremanuelj cytogeneticmappingof35newmarkersinthealpacavicugnapacos AT gutierrezgustavoa cytogeneticmappingof35newmarkersinthealpacavicugnapacos AT poncedeleonfabel cytogeneticmappingof35newmarkersinthealpacavicugnapacos |
| _version_ |
1806039424604045312 |