Neuropharmacological effects of essential oil from the leaves of Croton conduplicatus Kunth and possible mechanisms of action involved.
Ethnopharmacological relevance: Croton conduplicatus Kunth (Euphorbiaceae) is a Brazilian aromatic medicinal plant, widely known as ?quebra-faca?. In folk medicine, its leaves and stem-barks are used as a natural analgesic for the treatment of headaches. Aim of the study: In this study, we describe for the first time the neuropharmacological potential of the essential oil obtained from the leaves of Croton conduplicatus (EO) in experimental models of pain, anxiety and insomnia. The mechanisms of action involved in these activities were also investigated.
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| Format: | Artigo de periódico biblioteca |
| Language: | English eng |
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2018-04-26
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| Subjects: | Ansiedade, Dor, Insônia, Bioma Caatinga, Planta nativa, Quebra faca, Essential oil, Insomnia, Óleo essencial, Planta medicinal, Recurso natural, Anxiety, Pain, Medicinal plants, |
| Online Access: | http://www.alice.cnptia.embrapa.br/alice/handle/doc/1090904 |
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dig-alice-doc-10909042018-04-27T00:38:04Z Neuropharmacological effects of essential oil from the leaves of Croton conduplicatus Kunth and possible mechanisms of action involved. OLIVEIRA JÚNIOR, R. G. de FERRAZ, C. A. A. SILVA, J. C. TELES. R. B. de A. SILVA, M. G. DINIZ, T. C. SANTOS, U. S. dos SOUZA, A. V. de NUNES, C. E. P. SALVADOR, M. J. LORENZO, V. P. QUINTANS JÚNIOR, L. J. ALMEIDA, J. R. G. da S. RAIMUNDO GONÇALVES DE OLIVEIRA JÚNIOR, Núcleo de Estudos e Pesquisas de Plantas Medicinais (NEPLAME), Universidade Federal do Vale do São Francisco (UNIVASF), Petrolina, PE; CHRISTIANE ADRIELLY ALVES FERRAZ, Núcleo de Estudos e Pesquisas de Plantas Medicinais (NEPLAME), Universidade Federal do Vale do São Francisco (UNIVASF), Petrolina, PE; JULIANE CABRAL SILVA, Núcleo de Estudos e Pesquisas de Plantas Medicinais (NEPLAME), Universidade Federal do Vale do São Francisco (UNIVASF), Petrolina, PE; ROXANA BRAGA DE ANDRADE TELES, Núcleo de Estudos e Pesquisas de Plantas Medicinais (NEPLAME), Universidade Federal do Vale do São Francisco (UNIVASF), Petrolina, PE; MARIANA GAMA SILVA, Núcleo de Estudos e Pesquisas de Plantas Medicinais (NEPLAME), Universidade Federal do Vale do São Francisco (UNIVASF), Petrolina, PE; TÂMARA COIMBRA DINIZ, Núcleo de Estudos e Pesquisas de Plantas Medicinais (NEPLAME), Universidade Federal do Vale do São Francisco (UNIVASF), Petrolina, PE; UILIANE SOARES DOS SANTOS; ANA VALERIA VIEIRA DE SOUZA, CPATSA; CARLOS EDUARDO PEREIRA NUNES, Instituto de Biologia, Universidade Estadual de Campinas (UNICAMP), Campinas, SP; MARCOS JOSÉ SALVADOR, Instituto de Biologia, Universidade Estadual de Campinas (UNICAMP), Campinas, SP; VITOR PRATES LORENZO, Instituto Federal de Educação, Ciência e Tecnologia Sertão Pernambucano, Petrolina, PE; LUCINDO JOSÉ QUINTANS JÚNIOR, Departamento de Fisiologia, Universidade Federal de Sergipe (UFS), São Cristóvão, Sergipe; JACKSON ROBERTO GUEDES DA SILVA ALMEIDA, Núcleo de Estudos e Pesquisas de Plantas Medicinais (NEPLAME), Universidade Federal do Vale do São Francisco (UNIVASF), Petrolina, PE. Ansiedade Dor Insônia Bioma Caatinga Planta nativa Quebra faca Essential oil Insomnia Óleo essencial Planta medicinal Recurso natural Anxiety Pain Medicinal plants Ethnopharmacological relevance: Croton conduplicatus Kunth (Euphorbiaceae) is a Brazilian aromatic medicinal plant, widely known as ?quebra-faca?. In folk medicine, its leaves and stem-barks are used as a natural analgesic for the treatment of headaches. Aim of the study: In this study, we describe for the first time the neuropharmacological potential of the essential oil obtained from the leaves of Croton conduplicatus (EO) in experimental models of pain, anxiety and insomnia. The mechanisms of action involved in these activities were also investigated. 2018-04-27T00:37:57Z 2018-04-27T00:37:57Z 2018-04-26 2018 2018-05-02T11:11:11Z Artigo de periódico Journal of Ethnopharmacology, v. 221, p. 65–76, 2018. http://www.alice.cnptia.embrapa.br/alice/handle/doc/1090904 10.1016/j.jep.2018.04.009 en eng openAccess |
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| language |
English eng |
| topic |
Ansiedade Dor Insônia Bioma Caatinga Planta nativa Quebra faca Essential oil Insomnia Óleo essencial Planta medicinal Recurso natural Anxiety Pain Medicinal plants Ansiedade Dor Insônia Bioma Caatinga Planta nativa Quebra faca Essential oil Insomnia Óleo essencial Planta medicinal Recurso natural Anxiety Pain Medicinal plants |
| spellingShingle |
Ansiedade Dor Insônia Bioma Caatinga Planta nativa Quebra faca Essential oil Insomnia Óleo essencial Planta medicinal Recurso natural Anxiety Pain Medicinal plants Ansiedade Dor Insônia Bioma Caatinga Planta nativa Quebra faca Essential oil Insomnia Óleo essencial Planta medicinal Recurso natural Anxiety Pain Medicinal plants OLIVEIRA JÚNIOR, R. G. de FERRAZ, C. A. A. SILVA, J. C. TELES. R. B. de A. SILVA, M. G. DINIZ, T. C. SANTOS, U. S. dos SOUZA, A. V. de NUNES, C. E. P. SALVADOR, M. J. LORENZO, V. P. QUINTANS JÚNIOR, L. J. ALMEIDA, J. R. G. da S. Neuropharmacological effects of essential oil from the leaves of Croton conduplicatus Kunth and possible mechanisms of action involved. |
| description |
Ethnopharmacological relevance: Croton conduplicatus Kunth (Euphorbiaceae) is a Brazilian aromatic medicinal plant, widely known as ?quebra-faca?. In folk medicine, its leaves and stem-barks are used as a natural analgesic for the treatment of headaches. Aim of the study: In this study, we describe for the first time the neuropharmacological potential of the essential oil obtained from the leaves of Croton conduplicatus (EO) in experimental models of pain, anxiety and insomnia. The mechanisms of action involved in these activities were also investigated. |
| author2 |
RAIMUNDO GONÇALVES DE OLIVEIRA JÚNIOR, Núcleo de Estudos e Pesquisas de Plantas Medicinais (NEPLAME), Universidade Federal do Vale do São Francisco (UNIVASF), Petrolina, PE; CHRISTIANE ADRIELLY ALVES FERRAZ, Núcleo de Estudos e Pesquisas de Plantas Medicinais (NEPLAME), Universidade Federal do Vale do São Francisco (UNIVASF), Petrolina, PE; JULIANE CABRAL SILVA, Núcleo de Estudos e Pesquisas de Plantas Medicinais (NEPLAME), Universidade Federal do Vale do São Francisco (UNIVASF), Petrolina, PE; ROXANA BRAGA DE ANDRADE TELES, Núcleo de Estudos e Pesquisas de Plantas Medicinais (NEPLAME), Universidade Federal do Vale do São Francisco (UNIVASF), Petrolina, PE; MARIANA GAMA SILVA, Núcleo de Estudos e Pesquisas de Plantas Medicinais (NEPLAME), Universidade Federal do Vale do São Francisco (UNIVASF), Petrolina, PE; TÂMARA COIMBRA DINIZ, Núcleo de Estudos e Pesquisas de Plantas Medicinais (NEPLAME), Universidade Federal do Vale do São Francisco (UNIVASF), Petrolina, PE; UILIANE SOARES DOS SANTOS; ANA VALERIA VIEIRA DE SOUZA, CPATSA; CARLOS EDUARDO PEREIRA NUNES, Instituto de Biologia, Universidade Estadual de Campinas (UNICAMP), Campinas, SP; MARCOS JOSÉ SALVADOR, Instituto de Biologia, Universidade Estadual de Campinas (UNICAMP), Campinas, SP; VITOR PRATES LORENZO, Instituto Federal de Educação, Ciência e Tecnologia Sertão Pernambucano, Petrolina, PE; LUCINDO JOSÉ QUINTANS JÚNIOR, Departamento de Fisiologia, Universidade Federal de Sergipe (UFS), São Cristóvão, Sergipe; JACKSON ROBERTO GUEDES DA SILVA ALMEIDA, Núcleo de Estudos e Pesquisas de Plantas Medicinais (NEPLAME), Universidade Federal do Vale do São Francisco (UNIVASF), Petrolina, PE. |
| author_facet |
RAIMUNDO GONÇALVES DE OLIVEIRA JÚNIOR, Núcleo de Estudos e Pesquisas de Plantas Medicinais (NEPLAME), Universidade Federal do Vale do São Francisco (UNIVASF), Petrolina, PE; CHRISTIANE ADRIELLY ALVES FERRAZ, Núcleo de Estudos e Pesquisas de Plantas Medicinais (NEPLAME), Universidade Federal do Vale do São Francisco (UNIVASF), Petrolina, PE; JULIANE CABRAL SILVA, Núcleo de Estudos e Pesquisas de Plantas Medicinais (NEPLAME), Universidade Federal do Vale do São Francisco (UNIVASF), Petrolina, PE; ROXANA BRAGA DE ANDRADE TELES, Núcleo de Estudos e Pesquisas de Plantas Medicinais (NEPLAME), Universidade Federal do Vale do São Francisco (UNIVASF), Petrolina, PE; MARIANA GAMA SILVA, Núcleo de Estudos e Pesquisas de Plantas Medicinais (NEPLAME), Universidade Federal do Vale do São Francisco (UNIVASF), Petrolina, PE; TÂMARA COIMBRA DINIZ, Núcleo de Estudos e Pesquisas de Plantas Medicinais (NEPLAME), Universidade Federal do Vale do São Francisco (UNIVASF), Petrolina, PE; UILIANE SOARES DOS SANTOS; ANA VALERIA VIEIRA DE SOUZA, CPATSA; CARLOS EDUARDO PEREIRA NUNES, Instituto de Biologia, Universidade Estadual de Campinas (UNICAMP), Campinas, SP; MARCOS JOSÉ SALVADOR, Instituto de Biologia, Universidade Estadual de Campinas (UNICAMP), Campinas, SP; VITOR PRATES LORENZO, Instituto Federal de Educação, Ciência e Tecnologia Sertão Pernambucano, Petrolina, PE; LUCINDO JOSÉ QUINTANS JÚNIOR, Departamento de Fisiologia, Universidade Federal de Sergipe (UFS), São Cristóvão, Sergipe; JACKSON ROBERTO GUEDES DA SILVA ALMEIDA, Núcleo de Estudos e Pesquisas de Plantas Medicinais (NEPLAME), Universidade Federal do Vale do São Francisco (UNIVASF), Petrolina, PE. OLIVEIRA JÚNIOR, R. G. de FERRAZ, C. A. A. SILVA, J. C. TELES. R. B. de A. SILVA, M. G. DINIZ, T. C. SANTOS, U. S. dos SOUZA, A. V. de NUNES, C. E. P. SALVADOR, M. J. LORENZO, V. P. QUINTANS JÚNIOR, L. J. ALMEIDA, J. R. G. da S. |
| format |
Artigo de periódico |
| topic_facet |
Ansiedade Dor Insônia Bioma Caatinga Planta nativa Quebra faca Essential oil Insomnia Óleo essencial Planta medicinal Recurso natural Anxiety Pain Medicinal plants |
| author |
OLIVEIRA JÚNIOR, R. G. de FERRAZ, C. A. A. SILVA, J. C. TELES. R. B. de A. SILVA, M. G. DINIZ, T. C. SANTOS, U. S. dos SOUZA, A. V. de NUNES, C. E. P. SALVADOR, M. J. LORENZO, V. P. QUINTANS JÚNIOR, L. J. ALMEIDA, J. R. G. da S. |
| author_sort |
OLIVEIRA JÚNIOR, R. G. de |
| title |
Neuropharmacological effects of essential oil from the leaves of Croton conduplicatus Kunth and possible mechanisms of action involved. |
| title_short |
Neuropharmacological effects of essential oil from the leaves of Croton conduplicatus Kunth and possible mechanisms of action involved. |
| title_full |
Neuropharmacological effects of essential oil from the leaves of Croton conduplicatus Kunth and possible mechanisms of action involved. |
| title_fullStr |
Neuropharmacological effects of essential oil from the leaves of Croton conduplicatus Kunth and possible mechanisms of action involved. |
| title_full_unstemmed |
Neuropharmacological effects of essential oil from the leaves of Croton conduplicatus Kunth and possible mechanisms of action involved. |
| title_sort |
neuropharmacological effects of essential oil from the leaves of croton conduplicatus kunth and possible mechanisms of action involved. |
| publishDate |
2018-04-26 |
| url |
http://www.alice.cnptia.embrapa.br/alice/handle/doc/1090904 |
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