Bos taurus breed:Holstein Transcriptome or Gene expression
Johne’s disease is a chronic infection of the intestinal mucosa caused by Mycobacterium avium subspecies paratuberculosis (MAP). The events of pathogen survival, inflammation and progression to the clinical stages of infection are poorly understood. This study examines gene expression in the ileoceocal valve (ICV) of Holstein dairy cows at different stages of MAP infection. The ICV is known to be a primary site of MAP colonization and provides an ideal location to identify genes that are relevant to the progression of this disease. RNA was prepared from ICV tissues and RNA-Seq was used to compare gene transcription between clinical, subclinical, and negative control animals.
Saved in:
| Main Author: | |
|---|---|
| Format: | Dataset biblioteca |
| Published: |
2015
|
| Subjects: | Genetics, Bos taurus, eEukaryotes, transcriptome, |
| Online Access: | https://figshare.com/articles/dataset/Bos_taurus_breed_Holstein_Transcriptome_or_Gene_expression/25155023 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| id |
dat-usda-us-article25155023 |
|---|---|
| record_format |
figshare |
| spelling |
dat-usda-us-article251550232015-07-20T00:00:00Z Bos taurus breed:Holstein Transcriptome or Gene expression USDA-ARS-NADC (17912930) Genetics Bos taurus eEukaryotes transcriptome Johne’s disease is a chronic infection of the intestinal mucosa caused by Mycobacterium avium subspecies paratuberculosis (MAP). The events of pathogen survival, inflammation and progression to the clinical stages of infection are poorly understood. This study examines gene expression in the ileoceocal valve (ICV) of Holstein dairy cows at different stages of MAP infection. The ICV is known to be a primary site of MAP colonization and provides an ideal location to identify genes that are relevant to the progression of this disease. RNA was prepared from ICV tissues and RNA-Seq was used to compare gene transcription between clinical, subclinical, and negative control animals. 2015-07-20T00:00:00Z Dataset Dataset 10113/AF25155023 https://figshare.com/articles/dataset/Bos_taurus_breed_Holstein_Transcriptome_or_Gene_expression/25155023 Copyright Undetermined |
| institution |
USDA US |
| collection |
Figshare |
| country |
Estados Unidos |
| countrycode |
US |
| component |
Datos de investigación |
| access |
En linea |
| databasecode |
dat-usda-us |
| tag |
biblioteca |
| region |
America del Norte |
| libraryname |
National Agricultural Library of USDA |
| topic |
Genetics Bos taurus eEukaryotes transcriptome |
| spellingShingle |
Genetics Bos taurus eEukaryotes transcriptome USDA-ARS-NADC (17912930) Bos taurus breed:Holstein Transcriptome or Gene expression |
| description |
Johne’s disease is a chronic infection of the intestinal mucosa caused by Mycobacterium avium subspecies paratuberculosis (MAP). The events of pathogen survival, inflammation and progression to the clinical stages of infection are poorly understood. This study examines gene expression in the ileoceocal valve (ICV) of Holstein dairy cows at different stages of MAP infection. The ICV is known to be a primary site of MAP colonization and provides an ideal location to identify genes that are relevant to the progression of this disease. RNA was prepared from ICV tissues and RNA-Seq was used to compare gene transcription between clinical, subclinical, and negative control animals. |
| format |
Dataset |
| author |
USDA-ARS-NADC (17912930) |
| author_facet |
USDA-ARS-NADC (17912930) |
| author_sort |
USDA-ARS-NADC (17912930) |
| title |
Bos taurus breed:Holstein Transcriptome or Gene expression |
| title_short |
Bos taurus breed:Holstein Transcriptome or Gene expression |
| title_full |
Bos taurus breed:Holstein Transcriptome or Gene expression |
| title_fullStr |
Bos taurus breed:Holstein Transcriptome or Gene expression |
| title_full_unstemmed |
Bos taurus breed:Holstein Transcriptome or Gene expression |
| title_sort |
bos taurus breed:holstein transcriptome or gene expression |
| publishDate |
2015 |
| url |
https://figshare.com/articles/dataset/Bos_taurus_breed_Holstein_Transcriptome_or_Gene_expression/25155023 |
| work_keys_str_mv |
AT usdaarsnadc17912930 bostaurusbreedholsteintranscriptomeorgeneexpression |
| _version_ |
1813294675523534848 |