RNAseq analysis of Campylobacter jejuni sRNA CjNC140 mutants

RNAseq analysis of Campylobacter jejuni sRNA CjNC140 mutants

Campylobacter jejuni is an important zoonotic pathogen that possesses the ability to cause gastroenteritis in humans and abortion in ruminants. To study the molecular mechanisms that affect the virulence of various strains, we utilized knockout mutants of small RNA CjNC140 and CjNC110, and harvested RNA during exponential and stationary growth to examine the transcriptomes of these mutants compared to wild-type of the sheep abortion clone (IA3902). The results from this study were used to inform phenotypic studies assessing the role of these genes in the pathogenesis of disease of C. jejuni.

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Bibliographic Details
Main Author: Iowa State University College of Veterinary Medicine (18797518)
Format: Dataset biblioteca
Published: 2022
Subjects:Genetics, raw sequence reads,
Online Access:https://figshare.com/articles/dataset/RNAseq_analysis_of_Campylobacter_jejuni_sRNA_CjNC140_mutants/25090742
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id dat-usda-us-article25090742
record_format figshare
spelling dat-usda-us-article250907422022-12-01T00:00:00Z RNAseq analysis of Campylobacter jejuni sRNA CjNC140 mutants Iowa State University College of Veterinary Medicine (18797518) Genetics raw sequence reads Campylobacter jejuni is an important zoonotic pathogen that possesses the ability to cause gastroenteritis in humans and abortion in ruminants. To study the molecular mechanisms that affect the virulence of various strains, we utilized knockout mutants of small RNA CjNC140 and CjNC110, and harvested RNA during exponential and stationary growth to examine the transcriptomes of these mutants compared to wild-type of the sheep abortion clone (IA3902). The results from this study were used to inform phenotypic studies assessing the role of these genes in the pathogenesis of disease of C. jejuni. 2022-12-01T00:00:00Z Dataset Dataset 10113/AF25090742 https://figshare.com/articles/dataset/RNAseq_analysis_of_Campylobacter_jejuni_sRNA_CjNC140_mutants/25090742 Copyright Undetermined
institution USDA US
collection Figshare
country Estados Unidos
countrycode US
component Datos de investigación
access En linea
databasecode dat-usda-us
tag biblioteca
region America del Norte
libraryname National Agricultural Library of USDA
topic Genetics
raw sequence reads
spellingShingle Genetics
raw sequence reads
Iowa State University College of Veterinary Medicine (18797518)
RNAseq analysis of Campylobacter jejuni sRNA CjNC140 mutants
description Campylobacter jejuni is an important zoonotic pathogen that possesses the ability to cause gastroenteritis in humans and abortion in ruminants. To study the molecular mechanisms that affect the virulence of various strains, we utilized knockout mutants of small RNA CjNC140 and CjNC110, and harvested RNA during exponential and stationary growth to examine the transcriptomes of these mutants compared to wild-type of the sheep abortion clone (IA3902). The results from this study were used to inform phenotypic studies assessing the role of these genes in the pathogenesis of disease of C. jejuni.
format Dataset
author Iowa State University College of Veterinary Medicine (18797518)
author_facet Iowa State University College of Veterinary Medicine (18797518)
author_sort Iowa State University College of Veterinary Medicine (18797518)
title RNAseq analysis of Campylobacter jejuni sRNA CjNC140 mutants
title_short RNAseq analysis of Campylobacter jejuni sRNA CjNC140 mutants
title_full RNAseq analysis of Campylobacter jejuni sRNA CjNC140 mutants
title_fullStr RNAseq analysis of Campylobacter jejuni sRNA CjNC140 mutants
title_full_unstemmed RNAseq analysis of Campylobacter jejuni sRNA CjNC140 mutants
title_sort rnaseq analysis of campylobacter jejuni srna cjnc140 mutants
publishDate 2022
url https://figshare.com/articles/dataset/RNAseq_analysis_of_Campylobacter_jejuni_sRNA_CjNC140_mutants/25090742
work_keys_str_mv AT iowastateuniversitycollegeofveterinarymedicine18797518 rnaseqanalysisofcampylobacterjejunisrnacjnc140mutants
_version_ 1808944494026948608

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