Giardia intestinalis strain:Be-2 Genome sequencing

Giardia lamblia, a single-celled eukaryotic parasite, is a major cause of waterborne infection throughout the world. G. lamblia infects a wide range of mammalian hosts and is subdivided into eight genetically well-defined assemblages; named A through H. Previously, molecular studies have revealed that most of the assemblages are associated with animal infection, whereas only AI, AII, and B are responsible for human infection. However, fragmented genomes and lack of comparative analysis within and between the assemblages impede the understanding of the molecular mechanisms of host specificity, and differential diseases outcome due to giardiasis. Thus, in the current study, we are conducting comparative genomics using assemblage A and assemblage B isolates derived by axenic culture utilizing a hybrid Nanopore/Illumina sequencing approach.

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Bibliographic Details
Main Author: Contact; Asis Khan, USDA-ARS Animal Parasitic Diseases Lab (18797476)
Format: Dataset biblioteca
Published: 2022
Subjects:Genetics, Giardia intestinalis, Be-2, eEukaryotes, genome sequencing,
Online Access:https://figshare.com/articles/dataset/Giardia_intestinalis_strain_Be-2_Genome_sequencing/25090685
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record_format figshare
spelling dat-usda-us-article250906852022-11-21T00:00:00Z Giardia intestinalis strain:Be-2 Genome sequencing Contact; Asis Khan, USDA-ARS Animal Parasitic Diseases Lab (18797476) Genetics Giardia intestinalis Be-2 eEukaryotes genome sequencing Giardia lamblia, a single-celled eukaryotic parasite, is a major cause of waterborne infection throughout the world. G. lamblia infects a wide range of mammalian hosts and is subdivided into eight genetically well-defined assemblages; named A through H. Previously, molecular studies have revealed that most of the assemblages are associated with animal infection, whereas only AI, AII, and B are responsible for human infection. However, fragmented genomes and lack of comparative analysis within and between the assemblages impede the understanding of the molecular mechanisms of host specificity, and differential diseases outcome due to giardiasis. Thus, in the current study, we are conducting comparative genomics using assemblage A and assemblage B isolates derived by axenic culture utilizing a hybrid Nanopore/Illumina sequencing approach. 2022-11-21T00:00:00Z Dataset Dataset 10113/AF25090685 https://figshare.com/articles/dataset/Giardia_intestinalis_strain_Be-2_Genome_sequencing/25090685 Copyright Undetermined
institution USDA US
collection Figshare
country Estados Unidos
countrycode US
component Datos de investigación
access En linea
databasecode dat-usda-us
tag biblioteca
region America del Norte
libraryname National Agricultural Library of USDA
topic Genetics
Giardia intestinalis
Be-2
eEukaryotes
genome sequencing
spellingShingle Genetics
Giardia intestinalis
Be-2
eEukaryotes
genome sequencing
Contact; Asis Khan, USDA-ARS Animal Parasitic Diseases Lab (18797476)
Giardia intestinalis strain:Be-2 Genome sequencing
description Giardia lamblia, a single-celled eukaryotic parasite, is a major cause of waterborne infection throughout the world. G. lamblia infects a wide range of mammalian hosts and is subdivided into eight genetically well-defined assemblages; named A through H. Previously, molecular studies have revealed that most of the assemblages are associated with animal infection, whereas only AI, AII, and B are responsible for human infection. However, fragmented genomes and lack of comparative analysis within and between the assemblages impede the understanding of the molecular mechanisms of host specificity, and differential diseases outcome due to giardiasis. Thus, in the current study, we are conducting comparative genomics using assemblage A and assemblage B isolates derived by axenic culture utilizing a hybrid Nanopore/Illumina sequencing approach.
format Dataset
author Contact; Asis Khan, USDA-ARS Animal Parasitic Diseases Lab (18797476)
author_facet Contact; Asis Khan, USDA-ARS Animal Parasitic Diseases Lab (18797476)
author_sort Contact; Asis Khan, USDA-ARS Animal Parasitic Diseases Lab (18797476)
title Giardia intestinalis strain:Be-2 Genome sequencing
title_short Giardia intestinalis strain:Be-2 Genome sequencing
title_full Giardia intestinalis strain:Be-2 Genome sequencing
title_fullStr Giardia intestinalis strain:Be-2 Genome sequencing
title_full_unstemmed Giardia intestinalis strain:Be-2 Genome sequencing
title_sort giardia intestinalis strain:be-2 genome sequencing
publishDate 2022
url https://figshare.com/articles/dataset/Giardia_intestinalis_strain_Be-2_Genome_sequencing/25090685
work_keys_str_mv AT contactasiskhanusdaarsanimalparasiticdiseaseslab18797476 giardiaintestinalisstrainbe2genomesequencing
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