Data from: Lacticaseibacillus rhamnosus Strain GG (LGG) Regulate Gut Microbial Metabolites, an In Vitro Study Using Three Mature Human Gut Microbial Cultures in a Simulator of Human Intestinal Microbial Ecosystem (SHIME)

<p>Using the SHIME (an in vitro simulator of the human gut microbiome) we studied changes in the gut metabolome that occurred in response to the administration of the Laticaseibacillus rhamnosus strain GG (LGG). Using fecal inoculum from three healthy human donors, reactors were established representing three colonic regions and both the luminal and mucosal microbiome in those regions. Samples were collected before, during, and after inoculation of the reactors with LGG. </p> <p>This dataset includes untargeted metabolomics data. Shallow shotgun metagenomic sequencing data can be found in the NCBI Sequence Read Archive associated with BioProject PRJNA893635 : <a href="https://www.ncbi.nlm.nih.gov/bioproject/PRJNA893635">https://www.ncbi.nlm.nih.gov/bioproject/PRJNA893635</a>. </p> <p>Resources in this dataset:</p> <ul> <li> <p>Resource Title: Batch normalized metabolite peak area data File Name: metabolites_individual_samples_batch_norm_non_imputed.csv</p> </li> <li> <p>Resource Title: Sample metadata File Name: LGG2_metadata.csv</p> </li> </ul>

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Bibliographic Details
Main Authors: Karley K. Mahalak (17484798), Jenni Firrman (17484801), Jamshed T. Bobokalonov (17484804), LinShu Liu (17484807)
Format: Dataset biblioteca
Published: 2023
Subjects:Food sciences, Food nutritional balance, Ecology, Genetics, probiotics, metabolomics, NP306, data.gov, ARS,
Online Access:https://figshare.com/articles/dataset/Data_from_Lacticaseibacillus_rhamnosus_Strain_GG_LGG_Regulate_Gut_Microbial_Metabolites_an_In_Vitro_Study_Using_Three_Mature_Human_Gut_Microbial_Cultures_in_a_Simulator_of_Human_Intestinal_Microbial_Ecosystem_SHIME_/24857073
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spelling dat-usda-us-article248570732023-06-12T00:00:00Z Data from: Lacticaseibacillus rhamnosus Strain GG (LGG) Regulate Gut Microbial Metabolites, an In Vitro Study Using Three Mature Human Gut Microbial Cultures in a Simulator of Human Intestinal Microbial Ecosystem (SHIME) Karley K. Mahalak (17484798) Jenni Firrman (17484801) Jamshed T. Bobokalonov (17484804) LinShu Liu (17484807) Food sciences Food nutritional balance Ecology Genetics probiotics metabolomics NP306 data.gov ARS <p>Using the SHIME (an in vitro simulator of the human gut microbiome) we studied changes in the gut metabolome that occurred in response to the administration of the Laticaseibacillus rhamnosus strain GG (LGG). Using fecal inoculum from three healthy human donors, reactors were established representing three colonic regions and both the luminal and mucosal microbiome in those regions. Samples were collected before, during, and after inoculation of the reactors with LGG. </p> <p>This dataset includes untargeted metabolomics data. Shallow shotgun metagenomic sequencing data can be found in the NCBI Sequence Read Archive associated with BioProject PRJNA893635 : <a href="https://www.ncbi.nlm.nih.gov/bioproject/PRJNA893635">https://www.ncbi.nlm.nih.gov/bioproject/PRJNA893635</a>. </p> <p>Resources in this dataset:</p> <ul> <li> <p>Resource Title: Batch normalized metabolite peak area data File Name: metabolites_individual_samples_batch_norm_non_imputed.csv</p> </li> <li> <p>Resource Title: Sample metadata File Name: LGG2_metadata.csv</p> </li> </ul> 2023-06-12T00:00:00Z Dataset Dataset 10.15482/usda.adc/1529131 https://figshare.com/articles/dataset/Data_from_Lacticaseibacillus_rhamnosus_Strain_GG_LGG_Regulate_Gut_Microbial_Metabolites_an_In_Vitro_Study_Using_Three_Mature_Human_Gut_Microbial_Cultures_in_a_Simulator_of_Human_Intestinal_Microbial_Ecosystem_SHIME_/24857073 CC BY 4.0
institution USDA US
collection Figshare
country Estados Unidos
countrycode US
component Datos de investigación
access En linea
databasecode dat-usda-us
tag biblioteca
region America del Norte
libraryname National Agricultural Library of USDA
topic Food sciences
Food nutritional balance
Ecology
Genetics
probiotics
metabolomics
NP306
data.gov
ARS
spellingShingle Food sciences
Food nutritional balance
Ecology
Genetics
probiotics
metabolomics
NP306
data.gov
ARS
Karley K. Mahalak (17484798)
Jenni Firrman (17484801)
Jamshed T. Bobokalonov (17484804)
LinShu Liu (17484807)
Data from: Lacticaseibacillus rhamnosus Strain GG (LGG) Regulate Gut Microbial Metabolites, an In Vitro Study Using Three Mature Human Gut Microbial Cultures in a Simulator of Human Intestinal Microbial Ecosystem (SHIME)
description <p>Using the SHIME (an in vitro simulator of the human gut microbiome) we studied changes in the gut metabolome that occurred in response to the administration of the Laticaseibacillus rhamnosus strain GG (LGG). Using fecal inoculum from three healthy human donors, reactors were established representing three colonic regions and both the luminal and mucosal microbiome in those regions. Samples were collected before, during, and after inoculation of the reactors with LGG. </p> <p>This dataset includes untargeted metabolomics data. Shallow shotgun metagenomic sequencing data can be found in the NCBI Sequence Read Archive associated with BioProject PRJNA893635 : <a href="https://www.ncbi.nlm.nih.gov/bioproject/PRJNA893635">https://www.ncbi.nlm.nih.gov/bioproject/PRJNA893635</a>. </p> <p>Resources in this dataset:</p> <ul> <li> <p>Resource Title: Batch normalized metabolite peak area data File Name: metabolites_individual_samples_batch_norm_non_imputed.csv</p> </li> <li> <p>Resource Title: Sample metadata File Name: LGG2_metadata.csv</p> </li> </ul>
format Dataset
author Karley K. Mahalak (17484798)
Jenni Firrman (17484801)
Jamshed T. Bobokalonov (17484804)
LinShu Liu (17484807)
author_facet Karley K. Mahalak (17484798)
Jenni Firrman (17484801)
Jamshed T. Bobokalonov (17484804)
LinShu Liu (17484807)
author_sort Karley K. Mahalak (17484798)
title Data from: Lacticaseibacillus rhamnosus Strain GG (LGG) Regulate Gut Microbial Metabolites, an In Vitro Study Using Three Mature Human Gut Microbial Cultures in a Simulator of Human Intestinal Microbial Ecosystem (SHIME)
title_short Data from: Lacticaseibacillus rhamnosus Strain GG (LGG) Regulate Gut Microbial Metabolites, an In Vitro Study Using Three Mature Human Gut Microbial Cultures in a Simulator of Human Intestinal Microbial Ecosystem (SHIME)
title_full Data from: Lacticaseibacillus rhamnosus Strain GG (LGG) Regulate Gut Microbial Metabolites, an In Vitro Study Using Three Mature Human Gut Microbial Cultures in a Simulator of Human Intestinal Microbial Ecosystem (SHIME)
title_fullStr Data from: Lacticaseibacillus rhamnosus Strain GG (LGG) Regulate Gut Microbial Metabolites, an In Vitro Study Using Three Mature Human Gut Microbial Cultures in a Simulator of Human Intestinal Microbial Ecosystem (SHIME)
title_full_unstemmed Data from: Lacticaseibacillus rhamnosus Strain GG (LGG) Regulate Gut Microbial Metabolites, an In Vitro Study Using Three Mature Human Gut Microbial Cultures in a Simulator of Human Intestinal Microbial Ecosystem (SHIME)
title_sort data from: lacticaseibacillus rhamnosus strain gg (lgg) regulate gut microbial metabolites, an in vitro study using three mature human gut microbial cultures in a simulator of human intestinal microbial ecosystem (shime)
publishDate 2023
url https://figshare.com/articles/dataset/Data_from_Lacticaseibacillus_rhamnosus_Strain_GG_LGG_Regulate_Gut_Microbial_Metabolites_an_In_Vitro_Study_Using_Three_Mature_Human_Gut_Microbial_Cultures_in_a_Simulator_of_Human_Intestinal_Microbial_Ecosystem_SHIME_/24857073
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