Studies on the use of fractions from palm oil and palm kernel oil as suppository base materials.
In vitro studies were made of fractions from palm oil and cocoa butter substitute derived from palm kernel oil as suppository base materials. The dissolution of Sulphatizol and salicylic acid from suppositories made with fractions from palm oil and palm kernel oil was investigaged and compared with their dissiolution from suppositories made of cocoa gbutter and Witepsol, the two commonly used base materials. It was observed that the dissolution rates of Sulphatizol and salicylic acid from cocoa butter substitute and from a mixture on non-lauric cocoa butter substitute and hydrogenated palm kernel oil were faster than that of the same drugs from cocoa butter and Witepsol. The dissolution rates were increased by t he addition of 1% (w/w) Tween 80 to cocoa butter substitute. On storage, the dissolution rate of 1% Sulphatizol from cocoa butter substitute decreased, while that of salicylic acid remained constant.
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Subjects: | Aceite de palma, Aceite de palmiste, Ácido salicílico., fracciones de palma, Manteca de cacao., sulfatisol, |
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cat-fedepalma-221482022-08-05T00:04:22ZStudies on the use of fractions from palm oil and palm kernel oil as suppository base materials. Ooi, T.L, autor. aut 38699 Asma, D. 56063 Ch'ng, H.S. 54471 Leong, W.L. 49006 textS dIn vitro studies were made of fractions from palm oil and cocoa butter substitute derived from palm kernel oil as suppository base materials. The dissolution of Sulphatizol and salicylic acid from suppositories made with fractions from palm oil and palm kernel oil was investigaged and compared with their dissiolution from suppositories made of cocoa gbutter and Witepsol, the two commonly used base materials. It was observed that the dissolution rates of Sulphatizol and salicylic acid from cocoa butter substitute and from a mixture on non-lauric cocoa butter substitute and hydrogenated palm kernel oil were faster than that of the same drugs from cocoa butter and Witepsol. The dissolution rates were increased by t he addition of 1% (w/w) Tween 80 to cocoa butter substitute. On storage, the dissolution rate of 1% Sulphatizol from cocoa butter substitute decreased, while that of salicylic acid remained constant.2 referencias.In vitro studies were made of fractions from palm oil and cocoa butter substitute derived from palm kernel oil as suppository base materials. The dissolution of Sulphatizol and salicylic acid from suppositories made with fractions from palm oil and palm kernel oil was investigaged and compared with their dissiolution from suppositories made of cocoa gbutter and Witepsol, the two commonly used base materials. It was observed that the dissolution rates of Sulphatizol and salicylic acid from cocoa butter substitute and from a mixture on non-lauric cocoa butter substitute and hydrogenated palm kernel oil were faster than that of the same drugs from cocoa butter and Witepsol. The dissolution rates were increased by t he addition of 1% (w/w) Tween 80 to cocoa butter substitute. On storage, the dissolution rate of 1% Sulphatizol from cocoa butter substitute decreased, while that of salicylic acid remained constant.Aceite de palmaAceite de palmisteÁcido salicílico.fracciones de palmaManteca de cacao.sulfatisol |
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Aceite de palma Aceite de palmiste Ácido salicílico. fracciones de palma Manteca de cacao. sulfatisol Aceite de palma Aceite de palmiste Ácido salicílico. fracciones de palma Manteca de cacao. sulfatisol |
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Aceite de palma Aceite de palmiste Ácido salicílico. fracciones de palma Manteca de cacao. sulfatisol Aceite de palma Aceite de palmiste Ácido salicílico. fracciones de palma Manteca de cacao. sulfatisol Ooi, T.L, autor. aut 38699 Asma, D. 56063 Ch'ng, H.S. 54471 Leong, W.L. 49006 Studies on the use of fractions from palm oil and palm kernel oil as suppository base materials. |
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In vitro studies were made of fractions from palm oil and cocoa butter substitute derived from palm kernel oil as suppository base materials. The dissolution of Sulphatizol and salicylic acid from suppositories made with fractions from palm oil and palm kernel oil was investigaged and compared with their dissiolution from suppositories made of cocoa gbutter and Witepsol, the two commonly used base materials. It was observed that the dissolution rates of Sulphatizol and salicylic acid from cocoa butter substitute and from a mixture on non-lauric cocoa butter substitute and hydrogenated palm kernel oil were faster than that of the same drugs from cocoa butter and Witepsol. The dissolution rates were increased by t he addition of 1% (w/w) Tween 80 to cocoa butter substitute. On storage, the dissolution rate of 1% Sulphatizol from cocoa butter substitute decreased, while that of salicylic acid remained constant. |
format |
Texto |
topic_facet |
Aceite de palma Aceite de palmiste Ácido salicílico. fracciones de palma Manteca de cacao. sulfatisol |
author |
Ooi, T.L, autor. aut 38699 Asma, D. 56063 Ch'ng, H.S. 54471 Leong, W.L. 49006 |
author_facet |
Ooi, T.L, autor. aut 38699 Asma, D. 56063 Ch'ng, H.S. 54471 Leong, W.L. 49006 |
author_sort |
Ooi, T.L, autor. aut 38699 |
title |
Studies on the use of fractions from palm oil and palm kernel oil as suppository base materials. |
title_short |
Studies on the use of fractions from palm oil and palm kernel oil as suppository base materials. |
title_full |
Studies on the use of fractions from palm oil and palm kernel oil as suppository base materials. |
title_fullStr |
Studies on the use of fractions from palm oil and palm kernel oil as suppository base materials. |
title_full_unstemmed |
Studies on the use of fractions from palm oil and palm kernel oil as suppository base materials. |
title_sort |
studies on the use of fractions from palm oil and palm kernel oil as suppository base materials. |
work_keys_str_mv |
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