Intracellular Antibodies [electronic resource] : Development and Applications /
Recent advances in the field of recombinant antibodies have permitted the manipulation of genes encoding specific antibodies, thus allowing their ectopic expression in a wide variety of non-lymphoid cells. This volume describes how the ectopic expression of antibodies, as secreted or as intracellularly retargeted molecules, can be exploited to block biological functions or to confer new phenotypic traits (e.g. resistance to a virus). This is the first book describing this emerging technology, which is receiving increasing attention for application in many different fields and biological systems - from human gene therapy to plant biotechnology.
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Format: | Texto biblioteca |
Language: | eng |
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Berlin, Heidelberg : Springer Berlin Heidelberg : Imprint: Springer,
1997
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Subjects: | Life sciences., Immunology., Molecular biology., Biotechnology., Cell biology., Life Sciences., Cell Biology., Molecular Medicine., |
Online Access: | http://dx.doi.org/10.1007/978-3-662-07992-8 |
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KOHA-OAI-TEST:2261982018-07-31T00:06:57ZIntracellular Antibodies [electronic resource] : Development and Applications / Cattaneo, Antonino. editor. Biocca, Silvia. editor. SpringerLink (Online service) textBerlin, Heidelberg : Springer Berlin Heidelberg : Imprint: Springer,1997.engRecent advances in the field of recombinant antibodies have permitted the manipulation of genes encoding specific antibodies, thus allowing their ectopic expression in a wide variety of non-lymphoid cells. This volume describes how the ectopic expression of antibodies, as secreted or as intracellularly retargeted molecules, can be exploited to block biological functions or to confer new phenotypic traits (e.g. resistance to a virus). This is the first book describing this emerging technology, which is receiving increasing attention for application in many different fields and biological systems - from human gene therapy to plant biotechnology.1. Intracellular and Intercellular Immunization -- 2. Current Methods for Genotypic and Phenotypic Knock-Outs in Mammalian Cells -- 3. Recombinant Antibodies for Ectopic Expression -- 4. Assembly and Folding of Antibodies in Natural and Artificial Environments -- 5. Protein Sequence Motifs Involved in Intracellular Trafficking -- 6. Intercellular Immunization -- 7. Intracellular Immunization -- 8. Gene Therapy and Research Applications of Intrabodies for Human Infectious Diseases -- 9. Plantibodies: Immunomodulation and Immunotherapeutic Potential -- 10. From Phage Libraries to Intracellular Immunization -- 11. Perspectives and Conclusions.Recent advances in the field of recombinant antibodies have permitted the manipulation of genes encoding specific antibodies, thus allowing their ectopic expression in a wide variety of non-lymphoid cells. This volume describes how the ectopic expression of antibodies, as secreted or as intracellularly retargeted molecules, can be exploited to block biological functions or to confer new phenotypic traits (e.g. resistance to a virus). This is the first book describing this emerging technology, which is receiving increasing attention for application in many different fields and biological systems - from human gene therapy to plant biotechnology.Life sciences.Immunology.Molecular biology.Biotechnology.Cell biology.Life Sciences.Cell Biology.Immunology.Biotechnology.Molecular Medicine.Springer eBookshttp://dx.doi.org/10.1007/978-3-662-07992-8URN:ISBN:9783662079928 |
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Life sciences. Immunology. Molecular biology. Biotechnology. Cell biology. Life Sciences. Cell Biology. Immunology. Biotechnology. Molecular Medicine. Life sciences. Immunology. Molecular biology. Biotechnology. Cell biology. Life Sciences. Cell Biology. Immunology. Biotechnology. Molecular Medicine. |
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Life sciences. Immunology. Molecular biology. Biotechnology. Cell biology. Life Sciences. Cell Biology. Immunology. Biotechnology. Molecular Medicine. Life sciences. Immunology. Molecular biology. Biotechnology. Cell biology. Life Sciences. Cell Biology. Immunology. Biotechnology. Molecular Medicine. Cattaneo, Antonino. editor. Biocca, Silvia. editor. SpringerLink (Online service) Intracellular Antibodies [electronic resource] : Development and Applications / |
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Recent advances in the field of recombinant antibodies have permitted the manipulation of genes encoding specific antibodies, thus allowing their ectopic expression in a wide variety of non-lymphoid cells. This volume describes how the ectopic expression of antibodies, as secreted or as intracellularly retargeted molecules, can be exploited to block biological functions or to confer new phenotypic traits (e.g. resistance to a virus). This is the first book describing this emerging technology, which is receiving increasing attention for application in many different fields and biological systems - from human gene therapy to plant biotechnology. |
format |
Texto |
topic_facet |
Life sciences. Immunology. Molecular biology. Biotechnology. Cell biology. Life Sciences. Cell Biology. Immunology. Biotechnology. Molecular Medicine. |
author |
Cattaneo, Antonino. editor. Biocca, Silvia. editor. SpringerLink (Online service) |
author_facet |
Cattaneo, Antonino. editor. Biocca, Silvia. editor. SpringerLink (Online service) |
author_sort |
Cattaneo, Antonino. editor. |
title |
Intracellular Antibodies [electronic resource] : Development and Applications / |
title_short |
Intracellular Antibodies [electronic resource] : Development and Applications / |
title_full |
Intracellular Antibodies [electronic resource] : Development and Applications / |
title_fullStr |
Intracellular Antibodies [electronic resource] : Development and Applications / |
title_full_unstemmed |
Intracellular Antibodies [electronic resource] : Development and Applications / |
title_sort |
intracellular antibodies [electronic resource] : development and applications / |
publisher |
Berlin, Heidelberg : Springer Berlin Heidelberg : Imprint: Springer, |
publishDate |
1997 |
url |
http://dx.doi.org/10.1007/978-3-662-07992-8 |
work_keys_str_mv |
AT cattaneoantoninoeditor intracellularantibodieselectronicresourcedevelopmentandapplications AT bioccasilviaeditor intracellularantibodieselectronicresourcedevelopmentandapplications AT springerlinkonlineservice intracellularantibodieselectronicresourcedevelopmentandapplications |
_version_ |
1756270951648985088 |