Intracellular Antibodies [electronic resource] : Development and Applications /

Recent advances in the field of recombinant antibodies have permitted the manipulation of genes encoding specific antibodies, thus allowing their ectopic expression in a wide variety of non-lymphoid cells. This volume describes how the ectopic expression of antibodies, as secreted or as intracellularly retargeted molecules, can be exploited to block biological functions or to confer new phenotypic traits (e.g. resistance to a virus). This is the first book describing this emerging technology, which is receiving increasing attention for application in many different fields and biological systems - from human gene therapy to plant biotechnology.

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Bibliographic Details
Main Authors: Cattaneo, Antonino. editor., Biocca, Silvia. editor., SpringerLink (Online service)
Format: Texto biblioteca
Language:eng
Published: Berlin, Heidelberg : Springer Berlin Heidelberg : Imprint: Springer, 1997
Subjects:Life sciences., Immunology., Molecular biology., Biotechnology., Cell biology., Life Sciences., Cell Biology., Molecular Medicine.,
Online Access:http://dx.doi.org/10.1007/978-3-662-07992-8
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spelling KOHA-OAI-TEST:2261982018-07-31T00:06:57ZIntracellular Antibodies [electronic resource] : Development and Applications / Cattaneo, Antonino. editor. Biocca, Silvia. editor. SpringerLink (Online service) textBerlin, Heidelberg : Springer Berlin Heidelberg : Imprint: Springer,1997.engRecent advances in the field of recombinant antibodies have permitted the manipulation of genes encoding specific antibodies, thus allowing their ectopic expression in a wide variety of non-lymphoid cells. This volume describes how the ectopic expression of antibodies, as secreted or as intracellularly retargeted molecules, can be exploited to block biological functions or to confer new phenotypic traits (e.g. resistance to a virus). This is the first book describing this emerging technology, which is receiving increasing attention for application in many different fields and biological systems - from human gene therapy to plant biotechnology.1. Intracellular and Intercellular Immunization -- 2. Current Methods for Genotypic and Phenotypic Knock-Outs in Mammalian Cells -- 3. Recombinant Antibodies for Ectopic Expression -- 4. Assembly and Folding of Antibodies in Natural and Artificial Environments -- 5. Protein Sequence Motifs Involved in Intracellular Trafficking -- 6. Intercellular Immunization -- 7. Intracellular Immunization -- 8. Gene Therapy and Research Applications of Intrabodies for Human Infectious Diseases -- 9. Plantibodies: Immunomodulation and Immunotherapeutic Potential -- 10. From Phage Libraries to Intracellular Immunization -- 11. Perspectives and Conclusions.Recent advances in the field of recombinant antibodies have permitted the manipulation of genes encoding specific antibodies, thus allowing their ectopic expression in a wide variety of non-lymphoid cells. This volume describes how the ectopic expression of antibodies, as secreted or as intracellularly retargeted molecules, can be exploited to block biological functions or to confer new phenotypic traits (e.g. resistance to a virus). This is the first book describing this emerging technology, which is receiving increasing attention for application in many different fields and biological systems - from human gene therapy to plant biotechnology.Life sciences.Immunology.Molecular biology.Biotechnology.Cell biology.Life Sciences.Cell Biology.Immunology.Biotechnology.Molecular Medicine.Springer eBookshttp://dx.doi.org/10.1007/978-3-662-07992-8URN:ISBN:9783662079928
institution COLPOS
collection Koha
country México
countrycode MX
component Bibliográfico
access En linea
En linea
databasecode cat-colpos
tag biblioteca
region America del Norte
libraryname Departamento de documentación y biblioteca de COLPOS
language eng
topic Life sciences.
Immunology.
Molecular biology.
Biotechnology.
Cell biology.
Life Sciences.
Cell Biology.
Immunology.
Biotechnology.
Molecular Medicine.
Life sciences.
Immunology.
Molecular biology.
Biotechnology.
Cell biology.
Life Sciences.
Cell Biology.
Immunology.
Biotechnology.
Molecular Medicine.
spellingShingle Life sciences.
Immunology.
Molecular biology.
Biotechnology.
Cell biology.
Life Sciences.
Cell Biology.
Immunology.
Biotechnology.
Molecular Medicine.
Life sciences.
Immunology.
Molecular biology.
Biotechnology.
Cell biology.
Life Sciences.
Cell Biology.
Immunology.
Biotechnology.
Molecular Medicine.
Cattaneo, Antonino. editor.
Biocca, Silvia. editor.
SpringerLink (Online service)
Intracellular Antibodies [electronic resource] : Development and Applications /
description Recent advances in the field of recombinant antibodies have permitted the manipulation of genes encoding specific antibodies, thus allowing their ectopic expression in a wide variety of non-lymphoid cells. This volume describes how the ectopic expression of antibodies, as secreted or as intracellularly retargeted molecules, can be exploited to block biological functions or to confer new phenotypic traits (e.g. resistance to a virus). This is the first book describing this emerging technology, which is receiving increasing attention for application in many different fields and biological systems - from human gene therapy to plant biotechnology.
format Texto
topic_facet Life sciences.
Immunology.
Molecular biology.
Biotechnology.
Cell biology.
Life Sciences.
Cell Biology.
Immunology.
Biotechnology.
Molecular Medicine.
author Cattaneo, Antonino. editor.
Biocca, Silvia. editor.
SpringerLink (Online service)
author_facet Cattaneo, Antonino. editor.
Biocca, Silvia. editor.
SpringerLink (Online service)
author_sort Cattaneo, Antonino. editor.
title Intracellular Antibodies [electronic resource] : Development and Applications /
title_short Intracellular Antibodies [electronic resource] : Development and Applications /
title_full Intracellular Antibodies [electronic resource] : Development and Applications /
title_fullStr Intracellular Antibodies [electronic resource] : Development and Applications /
title_full_unstemmed Intracellular Antibodies [electronic resource] : Development and Applications /
title_sort intracellular antibodies [electronic resource] : development and applications /
publisher Berlin, Heidelberg : Springer Berlin Heidelberg : Imprint: Springer,
publishDate 1997
url http://dx.doi.org/10.1007/978-3-662-07992-8
work_keys_str_mv AT cattaneoantoninoeditor intracellularantibodieselectronicresourcedevelopmentandapplications
AT bioccasilviaeditor intracellularantibodieselectronicresourcedevelopmentandapplications
AT springerlinkonlineservice intracellularantibodieselectronicresourcedevelopmentandapplications
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