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Molecular Targeting and Signal Transduction [electronic resource] /
Our limited understanding of cellular regulatory signal-transduction-networks has been a barrier to progress in improving the overall cure-rate of human cancers. Delineation of the physiologic roles of the specific regulatory signaling components, with known association with metastatic phenotypes, is a highly promising area which will likely provide the next generation of targeted strategies in the future of molecular cancer medicine. These signaling components are likely to be used in diagnosis, prognosis, and as novel targets for therapeutic development. This book brings together up-to-date summaries by leading cancer researchers on the major principles of cancer cell biology: survival, apoptosis, adhesion, and cell cycle deregulation. It is directed at clinicians and scientists working in the areas of experimental and molecular therapeutics, molecular medicine, translational cancer research, and bio-medical sciences in general.
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| Main Authors: | , |
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| Format: | Texto biblioteca |
| Language: | eng |
| Published: |
Boston, MA : Springer US,
2004
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| Subjects: | Medicine., Cancer research., Oncology., Medicine & Public Health., Cancer Research., |
| Online Access: | http://dx.doi.org/10.1007/b105352 |
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KOHA-OAI-TEST:2075742018-07-30T23:37:48ZMolecular Targeting and Signal Transduction [electronic resource] / Kumar, Rakesh. editor. SpringerLink (Online service) textBoston, MA : Springer US,2004.engOur limited understanding of cellular regulatory signal-transduction-networks has been a barrier to progress in improving the overall cure-rate of human cancers. Delineation of the physiologic roles of the specific regulatory signaling components, with known association with metastatic phenotypes, is a highly promising area which will likely provide the next generation of targeted strategies in the future of molecular cancer medicine. These signaling components are likely to be used in diagnosis, prognosis, and as novel targets for therapeutic development. This book brings together up-to-date summaries by leading cancer researchers on the major principles of cancer cell biology: survival, apoptosis, adhesion, and cell cycle deregulation. It is directed at clinicians and scientists working in the areas of experimental and molecular therapeutics, molecular medicine, translational cancer research, and bio-medical sciences in general.Biology of the Epidermal Growth Factor Receptor Family -- Integrin Signaling in Cancer -- Regulators of Vascular Endothelial Growth Factor Expression in Cancer -- Integrin-Linked Kinase (ILK) in Combination Molecular Targeting -- P21-Activated Kinase 1: An Emerging Therapeutic Target -- Basis and Importance of SRC as a Target in Cancer -- Therapeutic Targeting of the Receptor Tyrosine Kinase Met -- Nuclear Factor-?B Activation Mediates Cellular Transformation, Proliferation, Invasion Angiogenesis and Metastasis of Cancer -- The P53 Pathway: Targets for the Development of Novel Cancer Therapeutics -- Runx Protein Signaling in Human Cancers -- Signal Transduction Mediated by Cyclin D1: from Mitogens to Cell Proliferation: A Molecular Target with Therapeutic Potential -- Signal Transduction Pathways in BCR-ABL Transformed Cells -- Estrogen Receptors and Anti-Estrogen Therapies -- Targeting Endothelin Axis in Cancer -- km23: A Novel TGF? Signaling Target Altered in Ovarian Cancer.Our limited understanding of cellular regulatory signal-transduction-networks has been a barrier to progress in improving the overall cure-rate of human cancers. Delineation of the physiologic roles of the specific regulatory signaling components, with known association with metastatic phenotypes, is a highly promising area which will likely provide the next generation of targeted strategies in the future of molecular cancer medicine. These signaling components are likely to be used in diagnosis, prognosis, and as novel targets for therapeutic development. This book brings together up-to-date summaries by leading cancer researchers on the major principles of cancer cell biology: survival, apoptosis, adhesion, and cell cycle deregulation. It is directed at clinicians and scientists working in the areas of experimental and molecular therapeutics, molecular medicine, translational cancer research, and bio-medical sciences in general.Medicine.Cancer research.Oncology.Medicine & Public Health.Oncology.Cancer Research.Springer eBookshttp://dx.doi.org/10.1007/b105352URN:ISBN:9781402078477 |
| institution |
COLPOS |
| collection |
Koha |
| country |
México |
| countrycode |
MX |
| component |
Bibliográfico |
| access |
En linea En linea |
| databasecode |
cat-colpos |
| tag |
biblioteca |
| region |
America del Norte |
| libraryname |
Departamento de documentación y biblioteca de COLPOS |
| language |
eng |
| topic |
Medicine. Cancer research. Oncology. Medicine & Public Health. Oncology. Cancer Research. Medicine. Cancer research. Oncology. Medicine & Public Health. Oncology. Cancer Research. |
| spellingShingle |
Medicine. Cancer research. Oncology. Medicine & Public Health. Oncology. Cancer Research. Medicine. Cancer research. Oncology. Medicine & Public Health. Oncology. Cancer Research. Kumar, Rakesh. editor. SpringerLink (Online service) Molecular Targeting and Signal Transduction [electronic resource] / |
| description |
Our limited understanding of cellular regulatory signal-transduction-networks has been a barrier to progress in improving the overall cure-rate of human cancers. Delineation of the physiologic roles of the specific regulatory signaling components, with known association with metastatic phenotypes, is a highly promising area which will likely provide the next generation of targeted strategies in the future of molecular cancer medicine. These signaling components are likely to be used in diagnosis, prognosis, and as novel targets for therapeutic development. This book brings together up-to-date summaries by leading cancer researchers on the major principles of cancer cell biology: survival, apoptosis, adhesion, and cell cycle deregulation. It is directed at clinicians and scientists working in the areas of experimental and molecular therapeutics, molecular medicine, translational cancer research, and bio-medical sciences in general. |
| format |
Texto |
| topic_facet |
Medicine. Cancer research. Oncology. Medicine & Public Health. Oncology. Cancer Research. |
| author |
Kumar, Rakesh. editor. SpringerLink (Online service) |
| author_facet |
Kumar, Rakesh. editor. SpringerLink (Online service) |
| author_sort |
Kumar, Rakesh. editor. |
| title |
Molecular Targeting and Signal Transduction [electronic resource] / |
| title_short |
Molecular Targeting and Signal Transduction [electronic resource] / |
| title_full |
Molecular Targeting and Signal Transduction [electronic resource] / |
| title_fullStr |
Molecular Targeting and Signal Transduction [electronic resource] / |
| title_full_unstemmed |
Molecular Targeting and Signal Transduction [electronic resource] / |
| title_sort |
molecular targeting and signal transduction [electronic resource] / |
| publisher |
Boston, MA : Springer US, |
| publishDate |
2004 |
| url |
http://dx.doi.org/10.1007/b105352 |
| work_keys_str_mv |
AT kumarrakesheditor moleculartargetingandsignaltransductionelectronicresource AT springerlinkonlineservice moleculartargetingandsignaltransductionelectronicresource |
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1756268403907100672 |