Molecular Mechanisms of Desensitization to Signal Molecules [electronic resource] /

Chemotaxis and Chemosensing -- Behavioral adaptation in prokaryotes -- Surface receptor mediated activation and adaptation of adenylate cyclase in Dictyostelium discoideum -- Adaptation of Dictyostelium discoideum cells to chemotactic signals -- Adaptation, periodic signalling, and receptor modification -- Adenylate Cyclase-Coupled Systems -- Glucagon desensitization of adenylate cyclase in hepatocytes: an action mediated by a distinct population of glucagon receptors coupled to stimulate inositol phospholipid metabolism -- Cellular adaptation to signal molecules: activation and interaction of different signal transduction systems -- Desensitization of the ?-adrenergic coupled adenylate cyclase. The ?-adrenergic receptor kinase phosphorylates agonist-occupied cyclase-coupled receptors -- Structural microheterogeneity of ß1-adrenoceptors in turkey erythrocytes and their functional consequences -- Adaptive response of beta-adrenergic sensitive adenylate cyclase system -- Hormone specific desensitization of Sertoli cell adenylate cyclase in a cell-free system -- Inositol Phospholipid-Coupled Systems -- Adaptations of receptor-dependent phosphatidylinositol 4,5-bisphosphate breakdown -- Cell responses to phosphoinositide-hydrolysing receptors: some potential sites of modulation -- The kinase C substrate protein B-50 and feedback control of synaptic signal transduction -- Retroinhibition of the calcium-phosphatidylinositol cascade by diacylglycerol in thyroid -- Visual Transduction -- Fast termination and adaptation processes in the cGMP cascade of visual transduction -- Phosphorylation of rhodopsin involved in terminating the visual response -- Ion Conductance -- Permeability control and desensitization by nicotinic acetylcholine receptors -- Cellular Systems -- Regulation of leukocyte responses to chemoattractants: role of receptors, guanine nucleotide regulatory (N) proteins and phospholipase C -- Modulation of macrophage oxygen metabolism. Evidence for desensitization and activation of the cell response to environmental stimuli -- Antibody induced down regulation of membrane receptors in human diseases -- Concluding Remarks.

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Bibliographic Details
Main Authors: Konijn, T. M. editor., Wel, H. Van der. editor., Haastert, P. J. M. Van. editor., Houslay, M. D. editor., Starre, H. Van der. editor., SpringerLink (Online service)
Format: Texto biblioteca
Language:eng
Published: Berlin, Heidelberg : Springer Berlin Heidelberg, 1987
Subjects:Life sciences., Pharmacology., Biochemistry., Cell biology., Life Sciences., Biochemistry, general., Cell Biology., Pharmacology/Toxicology.,
Online Access:http://dx.doi.org/10.1007/978-3-642-71782-6
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Summary:Chemotaxis and Chemosensing -- Behavioral adaptation in prokaryotes -- Surface receptor mediated activation and adaptation of adenylate cyclase in Dictyostelium discoideum -- Adaptation of Dictyostelium discoideum cells to chemotactic signals -- Adaptation, periodic signalling, and receptor modification -- Adenylate Cyclase-Coupled Systems -- Glucagon desensitization of adenylate cyclase in hepatocytes: an action mediated by a distinct population of glucagon receptors coupled to stimulate inositol phospholipid metabolism -- Cellular adaptation to signal molecules: activation and interaction of different signal transduction systems -- Desensitization of the ?-adrenergic coupled adenylate cyclase. The ?-adrenergic receptor kinase phosphorylates agonist-occupied cyclase-coupled receptors -- Structural microheterogeneity of ß1-adrenoceptors in turkey erythrocytes and their functional consequences -- Adaptive response of beta-adrenergic sensitive adenylate cyclase system -- Hormone specific desensitization of Sertoli cell adenylate cyclase in a cell-free system -- Inositol Phospholipid-Coupled Systems -- Adaptations of receptor-dependent phosphatidylinositol 4,5-bisphosphate breakdown -- Cell responses to phosphoinositide-hydrolysing receptors: some potential sites of modulation -- The kinase C substrate protein B-50 and feedback control of synaptic signal transduction -- Retroinhibition of the calcium-phosphatidylinositol cascade by diacylglycerol in thyroid -- Visual Transduction -- Fast termination and adaptation processes in the cGMP cascade of visual transduction -- Phosphorylation of rhodopsin involved in terminating the visual response -- Ion Conductance -- Permeability control and desensitization by nicotinic acetylcholine receptors -- Cellular Systems -- Regulation of leukocyte responses to chemoattractants: role of receptors, guanine nucleotide regulatory (N) proteins and phospholipase C -- Modulation of macrophage oxygen metabolism. Evidence for desensitization and activation of the cell response to environmental stimuli -- Antibody induced down regulation of membrane receptors in human diseases -- Concluding Remarks.