The Molecular Immunology of Complex Carbohydrates —2 [electronic resource] /

SECTION I Carbohydrate-Protein Interactions: Plant and Animal Lectins -- I-1 The Structural Basis for Carbohydrate Recognition by Lectins -- I-2 Lectin Cross-linking Interactions with Multivalent Carbohydrates -- I-3 Classification of Plant Lectins in Families of Structurally and Evolutionary Related Proteins -- I-4 Expression of Binding Properties of Gal/Ga1NAc Reactive Lectins by Mammalian Glycotopes -- I-5 ‘Glyco-Epitope’ Assignments for the Selectins: Advances Enabled by the Neoglycolipid Technology in Conjunction with Synthetic Carbohydrate Chemistry -- I-6 Animal Lectins: From Initial Description to Elaborated Structural and Functional Classification -- I-7 Galectins and Other Endogenous Carbohydrate-Binding Proteins of Animal Bladder -- I-8 Binding Properties and Applications of Aplysia Gonad Lectin -- I-9 Lectin and Anti-carbohydrate Antibody Assays Using Chemically Modified Ligands -- SECTION II Structure and Antigenicity of Glycoconjugates -- II-1 Intramolecular Carbohydrate-Protein Interaction -- II-2 Red Blood Cell Antigens Responsible for Inherited Types of Polyagglutination -- II-3 Antigenic Properties of Human Glycophorins—An Update -- II-4 KDN-Containing Glycoprotein from Loach Skin Mucus -- II-5 Glycoconjugates from Parasitic Helminths: Structure Diversity and Immunobiological Implications -- II-6 Glycosyl Phosphatidylinositol-Linked Glycoconjugates: Structure, Biosynthesis, and Function -- II-7 Enzymatic and Chemical Approaches for the Synthesis of Sialyl Glycoconjugates -- SECTION III Glycotopes Expression, Metabolism, and Functions -- III-1 The Genetic Regulation of Fucosylated and Sialylated Antigens on Developing Myeloid Cells -- III-2 Transcriptional Regulation of Expression of Carbohydrate Ligands for Cell Adhesion Molecules in the Selectin Family -- III-3 Biosynthesis and Function of ?1,6 Branched Mucin-Type Glycans -- III-4 Differentiation-Associated Expression of ß-N-acetylgalactosaminylated N-linked Oligosaccharides in Mammary Epithelial Cells -- III-5 Metabolism and Role of O-Acetylated Sialic Acids -- III-6 Contradictory Functions of the Sulfatide in the Blood Coagulation System -- III-7 Interaction of GM2 Activator Protein with Glycosphingolipids -- SECTION IV Complex Carbohydrates in Development and Treatment of Cancer -- IV-1 Tumor-Associated Carbohydrate Antigens Defining Tumor Malignancy: Basis for Development of Anti-cancer Vaccines -- IV-2 Carbohydrate-Mediated Adhesion of Human Colon Carcinoma Cells to Human Liver Sections -- IV-3 O-Linked N-Acetylglucosamine and Cancer: Messages from the Glycosylation of c-Myc -- IV-4 Analysis of a Murine Anti-Ganglioside GD2 Monoclonal Antibody Expressing Both IgG2a and IgG3 Isotypes: Monoclonality, Apoptosis Triggering, and Activation of Cellular Cytotoxicity on Human Melanoma Cells -- SECTION V Complex Carbohydrates in Microbial and Viral Infections and Vaccine Design -- V-1 Pathogen-Host Protein-Carbohydrate Interactions as the Basis of Important Infections -- V-2 Host Mediated Variation and Receptor Binding Specificity of Influenza Viruses -- V-3 Bacterial Polysaccharides as Vaccines — Immunity and Chemical Characterization -- V-4 The Conformational Epitope of Type III Group B Streptococcus Capsular Polysaccharide -- V-5 T-independent IgA Responses to Microbial Polysaccharides -- V-6 Protective Immunity and Gene Expression Related to Pneumococcal Glycoconjugates -- V-7 Structure and Functional Genomics of Lipopolysaccharide Expression in Haemophilus influenzae -- V-8 Molecular Mimicry of Host Structures by Lipooligosaccharides of Neisseria meningitidis: Characterization of Sialylated and Nonsialylated Lacto-N-Neotetraose (Gal?1-4G1cNAc?1-3Gal?1-4Glc) Structures in Lipooligosaccharides using Monoclonal Antibodies and Specific Lectins -- V-9 NMR and Molecular Modeling of Complex Carbohydrates and Carbohydrate-Protein Interactions: Applications to Anti-bacteria Vaccines -- Append -- A-I A Guide to the Carbohydrate Specificities of Applied Lectins-2 (Updated in 2000) -- A-II A Guide to Monoclonal Antibodies Directed to Glycotopes.

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Bibliographic Details
Main Authors: Wu, Albert M. editor., SpringerLink (Online service)
Format: Texto biblioteca
Language:eng
Published: Boston, MA : Springer US : Imprint: Springer, 2001
Subjects:Life sciences., Cancer research., Immunology., Biochemistry., Life Sciences., Biochemistry, general., Cancer Research.,
Online Access:http://dx.doi.org/10.1007/978-1-4615-1267-7
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Summary:SECTION I Carbohydrate-Protein Interactions: Plant and Animal Lectins -- I-1 The Structural Basis for Carbohydrate Recognition by Lectins -- I-2 Lectin Cross-linking Interactions with Multivalent Carbohydrates -- I-3 Classification of Plant Lectins in Families of Structurally and Evolutionary Related Proteins -- I-4 Expression of Binding Properties of Gal/Ga1NAc Reactive Lectins by Mammalian Glycotopes -- I-5 ‘Glyco-Epitope’ Assignments for the Selectins: Advances Enabled by the Neoglycolipid Technology in Conjunction with Synthetic Carbohydrate Chemistry -- I-6 Animal Lectins: From Initial Description to Elaborated Structural and Functional Classification -- I-7 Galectins and Other Endogenous Carbohydrate-Binding Proteins of Animal Bladder -- I-8 Binding Properties and Applications of Aplysia Gonad Lectin -- I-9 Lectin and Anti-carbohydrate Antibody Assays Using Chemically Modified Ligands -- SECTION II Structure and Antigenicity of Glycoconjugates -- II-1 Intramolecular Carbohydrate-Protein Interaction -- II-2 Red Blood Cell Antigens Responsible for Inherited Types of Polyagglutination -- II-3 Antigenic Properties of Human Glycophorins—An Update -- II-4 KDN-Containing Glycoprotein from Loach Skin Mucus -- II-5 Glycoconjugates from Parasitic Helminths: Structure Diversity and Immunobiological Implications -- II-6 Glycosyl Phosphatidylinositol-Linked Glycoconjugates: Structure, Biosynthesis, and Function -- II-7 Enzymatic and Chemical Approaches for the Synthesis of Sialyl Glycoconjugates -- SECTION III Glycotopes Expression, Metabolism, and Functions -- III-1 The Genetic Regulation of Fucosylated and Sialylated Antigens on Developing Myeloid Cells -- III-2 Transcriptional Regulation of Expression of Carbohydrate Ligands for Cell Adhesion Molecules in the Selectin Family -- III-3 Biosynthesis and Function of ?1,6 Branched Mucin-Type Glycans -- III-4 Differentiation-Associated Expression of ß-N-acetylgalactosaminylated N-linked Oligosaccharides in Mammary Epithelial Cells -- III-5 Metabolism and Role of O-Acetylated Sialic Acids -- III-6 Contradictory Functions of the Sulfatide in the Blood Coagulation System -- III-7 Interaction of GM2 Activator Protein with Glycosphingolipids -- SECTION IV Complex Carbohydrates in Development and Treatment of Cancer -- IV-1 Tumor-Associated Carbohydrate Antigens Defining Tumor Malignancy: Basis for Development of Anti-cancer Vaccines -- IV-2 Carbohydrate-Mediated Adhesion of Human Colon Carcinoma Cells to Human Liver Sections -- IV-3 O-Linked N-Acetylglucosamine and Cancer: Messages from the Glycosylation of c-Myc -- IV-4 Analysis of a Murine Anti-Ganglioside GD2 Monoclonal Antibody Expressing Both IgG2a and IgG3 Isotypes: Monoclonality, Apoptosis Triggering, and Activation of Cellular Cytotoxicity on Human Melanoma Cells -- SECTION V Complex Carbohydrates in Microbial and Viral Infections and Vaccine Design -- V-1 Pathogen-Host Protein-Carbohydrate Interactions as the Basis of Important Infections -- V-2 Host Mediated Variation and Receptor Binding Specificity of Influenza Viruses -- V-3 Bacterial Polysaccharides as Vaccines — Immunity and Chemical Characterization -- V-4 The Conformational Epitope of Type III Group B Streptococcus Capsular Polysaccharide -- V-5 T-independent IgA Responses to Microbial Polysaccharides -- V-6 Protective Immunity and Gene Expression Related to Pneumococcal Glycoconjugates -- V-7 Structure and Functional Genomics of Lipopolysaccharide Expression in Haemophilus influenzae -- V-8 Molecular Mimicry of Host Structures by Lipooligosaccharides of Neisseria meningitidis: Characterization of Sialylated and Nonsialylated Lacto-N-Neotetraose (Gal?1-4G1cNAc?1-3Gal?1-4Glc) Structures in Lipooligosaccharides using Monoclonal Antibodies and Specific Lectins -- V-9 NMR and Molecular Modeling of Complex Carbohydrates and Carbohydrate-Protein Interactions: Applications to Anti-bacteria Vaccines -- Append -- A-I A Guide to the Carbohydrate Specificities of Applied Lectins-2 (Updated in 2000) -- A-II A Guide to Monoclonal Antibodies Directed to Glycotopes.