Contemporary Nephrology [electronic resource] : Volume 5 /

1:Water Transport across ADH-Sensitive Epithelia -- 1. Introduction -- 2. A Working Hypothesis -- 3. Biochemical Aspects of the Mechanism of Action of ADH -- 4. Biophysics of Osmotic Water Flow -- 5. Experimental Bases for the Pore Hypothesis of Water Permeation -- 6. Role of the Cytoskeleton and Modulation of the Hydrosmotic Effect of ADH -- 7. Other Barriers to Osmotic Water Flow -- 8. Remaining Questions and Future Directions -- References -- 2:Renal Hemodynamics and Sodium Chloride Excretion -- 1. Renal Hemodynamics -- 2. Sodium Chloride Excretion and Regulation -- 3. Function of Discrete Nephron Segments -- 3:Renal Metabolism -- 1. Introduction -- 2. Renal Substrate Utilization -- 3. Effects of Acidosis on Renal Gene Expression -- 4. Adenosine in the Kidney -- 4:Acid-Base Physiology and Pathophysiology -- 1. Introduction -- 2. The Proximal Tubule -- 3. Bicarbonate Reabsorption in the Proximal Tubule -- 4. LoopofHenle -- 5. The Distal Nephron -- 6. Respiratory Acidosis -- 7. Effects of Acidosis -- 8. Ammonia and Urea -- 9. Lactic Acidosis -- 10. Miscellaneous or Global Studies of Acidification -- 11. Clinical Acid-Base Physiology -- 5:Mineral Metabolism -- 1. Inorganic Phosphate -- 2. Calcium -- 3. Vitamin D -- 4. Magnesium -- References -- 6:Sodium, Calcium, and Neurogenic Factors in the Pathogenesis of Essential Hypertension -- 1. Introduction -- 2. Salt and Hypertension -- 3. Calcium and Hypertension -- 4. Relation between Abnormalities of Sodium and Calcium Metabolism in Hypertension -- References -- 7:Immunologic Aspects of Renal Disease -- 1. Introduction -- 2. Mechanisms of Immune Glomerular Injury -- 3. Clinical Aspects of Immune Renal Disease -- 4. Diseases That Commonly Present as Nephrotic Syndrome -- 5. Glomerular Involvement in Systemic Diseases -- 8:Acute Renal Failure and Toxic Nephropathy -- 1. General Aspects -- 2. Cyclosporine -- 3. Aminoglycosides -- 4. Radiocontrast Agent Nephrotoxicity -- 5. Ischemic Acute Renal Failure -- 6. Role of Reactive Oxygen Species in Postischemic Renal Injury -- References -- 9:The Kidney in Systemic Disease -- 1. Introduction -- 2. Disorders of the Renal Microvasculature -- 3. Renal Consequences of Tumors -- References -- 10:Congenital Disorders of the Kidneys and Tumors: Alport’s Syndrome and Electrolyte and Metabolism Disorders in Apudomas -- 1. Alport’s Syndrome -- 2. Electrolyte and Metabolic Disorders in Apudomas -- 11:The Uremic Syndrome -- 1. Introduction -- 2. Uremic Toxins -- 3. Progression of Renal Dysfunction -- 4. The Skin -- 5. The Muscles and Joints -- 6. The Gastrointestinal System -- 7. Pulmonary System -- 8. The Cardiovascular System -- 9. The Hematopoietic System -- 10. The Immune System -- 11. The Nervous System -- 12. The Endocrine System -- 12:Nutrition in Renal Disease -- 1. Introduction -- 2. Progression of Renal Disease -- 3. Metabolism in Chronic Renal Failure -- 4. Nutritional Management of CRF Patients -- 5. Nephrotic Syndrome -- 6. Vitamins and Trace Elements -- 7. Nutrition and Renal Transplantation -- 8. Acute Renal Failure -- References -- 13:Dialysis -- 1. Erythropoietin -- 2. New Middle Molecules -- 3. Biocompatibility of Synthetic Membranes -- 4. Peritoneal Dialysis -- 5. Hemodynamic Response to Dialysis -- 6. Shortening Treatment Time -- 7. Filtration Modalities -- 8. Access -- References -- 14:Renal Transplantation -- 1. Introduction -- 2. Immunosuppression -- 3. Cellular Basis of Allograft Rejection -- 4. Tomorrow’s Shangri-la? -- References -- 15:Drugs and the Kidney -- 1. Introduction -- 2. Pharmacologic Principles and the Effects of Renal Disease -- 3. Drug Effects on Renal Function -- 4. Prescribing for Patients with Renal Dysfunction -- 5. Removal of Drugs by Extracorporeal Means and Peritoneal Dialysis -- 6. Aspects of Specific Drugs in Patients with Renal Disease -- 7. Drug Nephrotoxicity.