Immunobiology of Bacterial CpG-DNA [electronic resource] /

Bacterial CpG-DNA sequences not only serve for genetic information but act as "danger" signal to alert immune cells such as macrophages and dendritic cells. CpG-DNA directly causes activation of these members of the innate immune system yielding in up-regulation of co-stimulatory molecules and pro-inflammatory cytokines. As such they act as "natural" adjuvants to promote protective Th1 polarized T cell immune responses. This book is the first comprehensive review of the data emerging in this field.

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Bibliographic Details
Main Authors: Wagner, Hermann. editor., SpringerLink (Online service)
Format: Texto biblioteca
Language:eng
Published: Berlin, Heidelberg : Springer Berlin Heidelberg, 2000
Subjects:Medicine., Cancer research., Immunology., Microbiology., Biomedicine., Cancer Research.,
Online Access:http://dx.doi.org/10.1007/978-3-642-59672-8
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