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Immunobiology of Bacterial CpG-DNA [electronic resource] /
Bacterial CpG-DNA sequences not only serve for genetic information but act as "danger" signal to alert immune cells such as macrophages and dendritic cells. CpG-DNA directly causes activation of these members of the innate immune system yielding in up-regulation of co-stimulatory molecules and pro-inflammatory cytokines. As such they act as "natural" adjuvants to promote protective Th1 polarized T cell immune responses. This book is the first comprehensive review of the data emerging in this field.
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| Format: | Texto biblioteca |
| Language: | eng |
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Berlin, Heidelberg : Springer Berlin Heidelberg,
2000
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| Subjects: | Medicine., Cancer research., Immunology., Microbiology., Biomedicine., Cancer Research., |
| Online Access: | http://dx.doi.org/10.1007/978-3-642-59672-8 |
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KOHA-OAI-TEST:1779642018-07-30T22:56:45ZImmunobiology of Bacterial CpG-DNA [electronic resource] / Wagner, Hermann. editor. SpringerLink (Online service) textBerlin, Heidelberg : Springer Berlin Heidelberg,2000.engBacterial CpG-DNA sequences not only serve for genetic information but act as "danger" signal to alert immune cells such as macrophages and dendritic cells. CpG-DNA directly causes activation of these members of the innate immune system yielding in up-regulation of co-stimulatory molecules and pro-inflammatory cytokines. As such they act as "natural" adjuvants to promote protective Th1 polarized T cell immune responses. This book is the first comprehensive review of the data emerging in this field.List of Contents -- Mechanism of Action of CpG DNA -- Oligodeoxyribonucleotides with 5’-ACGT-3’ or 5’-TCGA-3’ Sequence Induce Production of Interferons -- Macrophage Activation by Immunostimulatory DNA -- Consequences of Bacterial CpG DNA-Driven Activation of Antigen-Presenting Cells -- Signal Transduction Pathways Activated by CpG-DNA -- CpG DNA Co-Stimulates Antigen-Reactive T Cells -- Role of Type I Interferons in T Cell Activation Induced by CpG DNA -- Hematopoietic Remodeling Triggered by CpG DNA -- CpG DNA Augments the Immunogenicity of Plasmid DNA Vaccines -- The Role of Bacterial DNA in Autoantibody Induction -- CpG DNA in Cancer Immunotherapy -- Use of CpG DNA for Enhancing Specific Immune Responses -- Immunostimulatory-Sequence DNA is an Effective Mucosal Adjuvant -- CpG DNA Switches on Th1 Immunity and Modulates Antigen-Presenting Cell Function -- Effects of CpG DNA on Th1/Th2 Balance in Asthma -- Responses of Human B Cells to DNA and Phosphorothioate Oligodeoxynucleotides.Bacterial CpG-DNA sequences not only serve for genetic information but act as "danger" signal to alert immune cells such as macrophages and dendritic cells. CpG-DNA directly causes activation of these members of the innate immune system yielding in up-regulation of co-stimulatory molecules and pro-inflammatory cytokines. As such they act as "natural" adjuvants to promote protective Th1 polarized T cell immune responses. This book is the first comprehensive review of the data emerging in this field.Medicine.Cancer research.Immunology.Microbiology.Biomedicine.Immunology.Microbiology.Cancer Research.Springer eBookshttp://dx.doi.org/10.1007/978-3-642-59672-8URN:ISBN:9783642596728 |
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Koha |
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México |
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biblioteca |
| region |
America del Norte |
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Departamento de documentación y biblioteca de COLPOS |
| language |
eng |
| topic |
Medicine. Cancer research. Immunology. Microbiology. Biomedicine. Immunology. Microbiology. Cancer Research. Medicine. Cancer research. Immunology. Microbiology. Biomedicine. Immunology. Microbiology. Cancer Research. |
| spellingShingle |
Medicine. Cancer research. Immunology. Microbiology. Biomedicine. Immunology. Microbiology. Cancer Research. Medicine. Cancer research. Immunology. Microbiology. Biomedicine. Immunology. Microbiology. Cancer Research. Wagner, Hermann. editor. SpringerLink (Online service) Immunobiology of Bacterial CpG-DNA [electronic resource] / |
| description |
Bacterial CpG-DNA sequences not only serve for genetic information but act as "danger" signal to alert immune cells such as macrophages and dendritic cells. CpG-DNA directly causes activation of these members of the innate immune system yielding in up-regulation of co-stimulatory molecules and pro-inflammatory cytokines. As such they act as "natural" adjuvants to promote protective Th1 polarized T cell immune responses. This book is the first comprehensive review of the data emerging in this field. |
| format |
Texto |
| topic_facet |
Medicine. Cancer research. Immunology. Microbiology. Biomedicine. Immunology. Microbiology. Cancer Research. |
| author |
Wagner, Hermann. editor. SpringerLink (Online service) |
| author_facet |
Wagner, Hermann. editor. SpringerLink (Online service) |
| author_sort |
Wagner, Hermann. editor. |
| title |
Immunobiology of Bacterial CpG-DNA [electronic resource] / |
| title_short |
Immunobiology of Bacterial CpG-DNA [electronic resource] / |
| title_full |
Immunobiology of Bacterial CpG-DNA [electronic resource] / |
| title_fullStr |
Immunobiology of Bacterial CpG-DNA [electronic resource] / |
| title_full_unstemmed |
Immunobiology of Bacterial CpG-DNA [electronic resource] / |
| title_sort |
immunobiology of bacterial cpg-dna [electronic resource] / |
| publisher |
Berlin, Heidelberg : Springer Berlin Heidelberg, |
| publishDate |
2000 |
| url |
http://dx.doi.org/10.1007/978-3-642-59672-8 |
| work_keys_str_mv |
AT wagnerhermanneditor immunobiologyofbacterialcpgdnaelectronicresource AT springerlinkonlineservice immunobiologyofbacterialcpgdnaelectronicresource |
| _version_ |
1756264346708606976 |