Multidrug-resistant pulmonary tuberculosis in Los Altos, Selva and Norte regions, Chiapas, Mexico

OBJECTIVES: To analyse the proportion of multidrugresistant tuberculosis (MDR-TB) in cultures performed during the period 2000-2002 in Los Altos, Selva and Norte regions, Chiapas, Mexico, and to analyse MDRTB in terms of clinical and sociodemographic indicators. METHODS: Cross-sectional study of patients with pulmonary tuberculosis (PTB) from the above regions. Drug susceptibility testing results from two research projects were analysed, as were those of routine sputum samples sent in by health personnel for processing (n = 114). MDR-TB was analysed in terms of the various variables of interest using bivariate tests of association and logistic regression. RESULTS: The proportion of primary MDR-TB was 4.6% (2 of 43), that of secondary MDR-TB was 29.2% (7/24), while among those whose history of treatment was unknown the proportion was 14.3% (3/21). According to the logistic regression model, the variables most highly associated with MDR-TB were as follows: having received anti-tuberculosis treatment previously, cough of >3 years' duration and not being indigenous. CONCLUSIONS: The high proportion of MDR cases found in the regions studied shows that it is necessary to signifi cantly improve the control and surveillance of PTB.

Bibliographic Details

Main Authors:	Sánchez Pérez, Héctor Javier 1960- Doctor 5453, Díaz Vázquez, A. autor/a, Nájera Ortíz, Juan Carlos autor/a 13779, Balandrano de Spindola, Susana autor/a, Martín Mateo, Miguel Luis autor/a 15127
Format:	Texto biblioteca
Language:	eng
Subjects:	Tuberculosis pulmonar, Resistencia a los medicamentos, Indicadores demográficos, Diagnóstico clínico, Artfrosur,
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