Real - rheumatoid arthritis in real life -study cohort: a sociodemographic profile of rheumatoid arthritis in Brazil
Abstract Background: In Brazil, socioeconomic differences in the incidence of rheumatoid arthritis (RA) have been demonstrated, which are important in the formulation of hypotheses regarding the association between environmental factors, lifestyle and the risk of disease development. This study examines how the socioeconomic condition of the patient with RA in Brazil, assessed according to social class, educational level, employment situation and use of caregivers, affects the times between the beginning of symptoms and diagnosis and the beginning of the use of disease-modifying antirheumatic drugs, as well as the presence of erosive disease and functional status. Methods: This work is part of a multicentric study called REAL - Rheumatoid Arthritis in Real Life in Brazil, which is a prospective observational cohort study. Results: As described in the REAL study, we included a total of 1115 patients. It was noted that patients with an educational classification of up to second grade incomplete presented with erosion percentages above those with a higher grade complete. Patients with caregivers presented a higher percentage of erosion than patients without caregivers. We verified that patients from economic classes above B2 presented fewer occurrences of erosion than those from classes C2, D-E. We also analyzed the average time differences from the beginning of symptoms and diagnosis and the beginning of treatment, according to academic level, erosion and economic classification. Patients with first grade complete showed an HAQ-DI averages higher than those with second grade complete. The patients who had employment showed lower HAQ-DI averages than patients who were not employed. The patients with erosion showed an HAQ-DI value higher than those without erosion. Patients with caregivers showed an HAQ-DI average higher than that of without caregivers. Conclusion: This study showed that the therapeutic window of RA is not being reached, and therefore we should have a policy to expand and ensure access to public health for all patients, especially those with lower levels of education and income. Trial registration: This study was approved by the National Commission of Ethics in Research.
Main Authors: | , , , , , , , , , , , , , |
---|---|
Format: | Digital revista |
Language: | English |
Published: |
Sociedade Brasileira de Reumatologia
2020
|
Online Access: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S2523-31062020000100215 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
id |
oai:scielo:S2523-31062020000100215 |
---|---|
record_format |
ojs |
spelling |
oai:scielo:S2523-310620200001002152020-03-23Real - rheumatoid arthritis in real life -study cohort: a sociodemographic profile of rheumatoid arthritis in BrazilSacilotto,Nathália de CarvalhoGiorgi,Rina Dalva NeubarthVargas-Santos,Ana BeatrizAlbuquerque,Cleandro Pires deRadominski,Sebastião CezarPereira,Ivânio AlvesGuimarães,Maria Fernanda Brandão ResendeBértolo,Manoel BarrosLouzada Jr,PauloSauma,Maria de Fátima Lobato da CunhaBonfiglioli,Karina RossiBrenol,Claiton ViegasMota,Licia Maria Henrique daCastelar-Pinheiro,Geraldo da Rocha Rheumatoid arthritis Demographic profile Public health Abstract Background: In Brazil, socioeconomic differences in the incidence of rheumatoid arthritis (RA) have been demonstrated, which are important in the formulation of hypotheses regarding the association between environmental factors, lifestyle and the risk of disease development. This study examines how the socioeconomic condition of the patient with RA in Brazil, assessed according to social class, educational level, employment situation and use of caregivers, affects the times between the beginning of symptoms and diagnosis and the beginning of the use of disease-modifying antirheumatic drugs, as well as the presence of erosive disease and functional status. Methods: This work is part of a multicentric study called REAL - Rheumatoid Arthritis in Real Life in Brazil, which is a prospective observational cohort study. Results: As described in the REAL study, we included a total of 1115 patients. It was noted that patients with an educational classification of up to second grade incomplete presented with erosion percentages above those with a higher grade complete. Patients with caregivers presented a higher percentage of erosion than patients without caregivers. We verified that patients from economic classes above B2 presented fewer occurrences of erosion than those from classes C2, D-E. We also analyzed the average time differences from the beginning of symptoms and diagnosis and the beginning of treatment, according to academic level, erosion and economic classification. Patients with first grade complete showed an HAQ-DI averages higher than those with second grade complete. The patients who had employment showed lower HAQ-DI averages than patients who were not employed. The patients with erosion showed an HAQ-DI value higher than those without erosion. Patients with caregivers showed an HAQ-DI average higher than that of without caregivers. Conclusion: This study showed that the therapeutic window of RA is not being reached, and therefore we should have a policy to expand and ensure access to public health for all patients, especially those with lower levels of education and income. Trial registration: This study was approved by the National Commission of Ethics in Research.info:eu-repo/semantics/openAccessSociedade Brasileira de ReumatologiaAdvances in Rheumatology v.60 20202020-01-01info:eu-repo/semantics/articletext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S2523-31062020000100215en10.1186/s42358-020-0121-5 |
institution |
SCIELO |
collection |
OJS |
country |
Brasil |
countrycode |
BR |
component |
Revista |
access |
En linea |
databasecode |
rev-scielo-br |
tag |
revista |
region |
America del Sur |
libraryname |
SciELO |
language |
English |
format |
Digital |
author |
Sacilotto,Nathália de Carvalho Giorgi,Rina Dalva Neubarth Vargas-Santos,Ana Beatriz Albuquerque,Cleandro Pires de Radominski,Sebastião Cezar Pereira,Ivânio Alves Guimarães,Maria Fernanda Brandão Resende Bértolo,Manoel Barros Louzada Jr,Paulo Sauma,Maria de Fátima Lobato da Cunha Bonfiglioli,Karina Rossi Brenol,Claiton Viegas Mota,Licia Maria Henrique da Castelar-Pinheiro,Geraldo da Rocha |
spellingShingle |
Sacilotto,Nathália de Carvalho Giorgi,Rina Dalva Neubarth Vargas-Santos,Ana Beatriz Albuquerque,Cleandro Pires de Radominski,Sebastião Cezar Pereira,Ivânio Alves Guimarães,Maria Fernanda Brandão Resende Bértolo,Manoel Barros Louzada Jr,Paulo Sauma,Maria de Fátima Lobato da Cunha Bonfiglioli,Karina Rossi Brenol,Claiton Viegas Mota,Licia Maria Henrique da Castelar-Pinheiro,Geraldo da Rocha Real - rheumatoid arthritis in real life -study cohort: a sociodemographic profile of rheumatoid arthritis in Brazil |
author_facet |
Sacilotto,Nathália de Carvalho Giorgi,Rina Dalva Neubarth Vargas-Santos,Ana Beatriz Albuquerque,Cleandro Pires de Radominski,Sebastião Cezar Pereira,Ivânio Alves Guimarães,Maria Fernanda Brandão Resende Bértolo,Manoel Barros Louzada Jr,Paulo Sauma,Maria de Fátima Lobato da Cunha Bonfiglioli,Karina Rossi Brenol,Claiton Viegas Mota,Licia Maria Henrique da Castelar-Pinheiro,Geraldo da Rocha |
author_sort |
Sacilotto,Nathália de Carvalho |
title |
Real - rheumatoid arthritis in real life -study cohort: a sociodemographic profile of rheumatoid arthritis in Brazil |
title_short |
Real - rheumatoid arthritis in real life -study cohort: a sociodemographic profile of rheumatoid arthritis in Brazil |
title_full |
Real - rheumatoid arthritis in real life -study cohort: a sociodemographic profile of rheumatoid arthritis in Brazil |
title_fullStr |
Real - rheumatoid arthritis in real life -study cohort: a sociodemographic profile of rheumatoid arthritis in Brazil |
title_full_unstemmed |
Real - rheumatoid arthritis in real life -study cohort: a sociodemographic profile of rheumatoid arthritis in Brazil |
title_sort |
real - rheumatoid arthritis in real life -study cohort: a sociodemographic profile of rheumatoid arthritis in brazil |
description |
Abstract Background: In Brazil, socioeconomic differences in the incidence of rheumatoid arthritis (RA) have been demonstrated, which are important in the formulation of hypotheses regarding the association between environmental factors, lifestyle and the risk of disease development. This study examines how the socioeconomic condition of the patient with RA in Brazil, assessed according to social class, educational level, employment situation and use of caregivers, affects the times between the beginning of symptoms and diagnosis and the beginning of the use of disease-modifying antirheumatic drugs, as well as the presence of erosive disease and functional status. Methods: This work is part of a multicentric study called REAL - Rheumatoid Arthritis in Real Life in Brazil, which is a prospective observational cohort study. Results: As described in the REAL study, we included a total of 1115 patients. It was noted that patients with an educational classification of up to second grade incomplete presented with erosion percentages above those with a higher grade complete. Patients with caregivers presented a higher percentage of erosion than patients without caregivers. We verified that patients from economic classes above B2 presented fewer occurrences of erosion than those from classes C2, D-E. We also analyzed the average time differences from the beginning of symptoms and diagnosis and the beginning of treatment, according to academic level, erosion and economic classification. Patients with first grade complete showed an HAQ-DI averages higher than those with second grade complete. The patients who had employment showed lower HAQ-DI averages than patients who were not employed. The patients with erosion showed an HAQ-DI value higher than those without erosion. Patients with caregivers showed an HAQ-DI average higher than that of without caregivers. Conclusion: This study showed that the therapeutic window of RA is not being reached, and therefore we should have a policy to expand and ensure access to public health for all patients, especially those with lower levels of education and income. Trial registration: This study was approved by the National Commission of Ethics in Research. |
publisher |
Sociedade Brasileira de Reumatologia |
publishDate |
2020 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S2523-31062020000100215 |
work_keys_str_mv |
AT sacilottonathaliadecarvalho realrheumatoidarthritisinreallifestudycohortasociodemographicprofileofrheumatoidarthritisinbrazil AT giorgirinadalvaneubarth realrheumatoidarthritisinreallifestudycohortasociodemographicprofileofrheumatoidarthritisinbrazil AT vargassantosanabeatriz realrheumatoidarthritisinreallifestudycohortasociodemographicprofileofrheumatoidarthritisinbrazil AT albuquerquecleandropiresde realrheumatoidarthritisinreallifestudycohortasociodemographicprofileofrheumatoidarthritisinbrazil AT radominskisebastiaocezar realrheumatoidarthritisinreallifestudycohortasociodemographicprofileofrheumatoidarthritisinbrazil AT pereiraivanioalves realrheumatoidarthritisinreallifestudycohortasociodemographicprofileofrheumatoidarthritisinbrazil AT guimaraesmariafernandabrandaoresende realrheumatoidarthritisinreallifestudycohortasociodemographicprofileofrheumatoidarthritisinbrazil AT bertolomanoelbarros realrheumatoidarthritisinreallifestudycohortasociodemographicprofileofrheumatoidarthritisinbrazil AT louzadajrpaulo realrheumatoidarthritisinreallifestudycohortasociodemographicprofileofrheumatoidarthritisinbrazil AT saumamariadefatimalobatodacunha realrheumatoidarthritisinreallifestudycohortasociodemographicprofileofrheumatoidarthritisinbrazil AT bonfigliolikarinarossi realrheumatoidarthritisinreallifestudycohortasociodemographicprofileofrheumatoidarthritisinbrazil AT brenolclaitonviegas realrheumatoidarthritisinreallifestudycohortasociodemographicprofileofrheumatoidarthritisinbrazil AT motaliciamariahenriqueda realrheumatoidarthritisinreallifestudycohortasociodemographicprofileofrheumatoidarthritisinbrazil AT castelarpinheirogeraldodarocha realrheumatoidarthritisinreallifestudycohortasociodemographicprofileofrheumatoidarthritisinbrazil |
_version_ |
1756441904933765120 |