Oral lichen planus and HCV infection

ABSTRACT Chronic infection by hepatitis C virus (HCV) can lead not only to the development of hepatic cirrhosis, but also to the emergence of extra-hepatic manifestations (EHMs), such as oral lichen planus (OLP). Here, we describe a clinical presentation of massive, erosive OLP in an HCV-positive patient whose clinical management was difficult. Full remission was achieved after sustained virological response by using direct-acting anti-retrovirals. This case report demonstrates not only the importance of diagnosing EHMs for identification of HCV infection, but also the importance of controlling it for management of OLP and EHMs.

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Bibliographic Details
Main Authors: Tenório,Jefferson R., Camargo,Alessandra Rodrigues de, Lemos,Celso, Ortega,Karem L.
Format: Digital revista
Language:English
Published: Hospital Universitário da Universidade de São Paulo 2020
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S2236-19602020000401101
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Description
Summary:ABSTRACT Chronic infection by hepatitis C virus (HCV) can lead not only to the development of hepatic cirrhosis, but also to the emergence of extra-hepatic manifestations (EHMs), such as oral lichen planus (OLP). Here, we describe a clinical presentation of massive, erosive OLP in an HCV-positive patient whose clinical management was difficult. Full remission was achieved after sustained virological response by using direct-acting anti-retrovirals. This case report demonstrates not only the importance of diagnosing EHMs for identification of HCV infection, but also the importance of controlling it for management of OLP and EHMs.