General aspects of the COVID-19 pandemic

General aspects of the COVID-19 pandemic

Abstract Objectives: to review the available literature on the general aspects of SARS-CoV-2 infec-tion. Methods: this is a narrative literature review carried out from March to September 2020. Results: COVID-19 caused by the new coronavirus or SARS-CoV-2, grows with devas-tating effects worldwide. The literature describes epidemiological data and mortality risk groups of the disease, which presents a high rate of transmission. Prevention is the most effective way to fight the disease, persisting the absence of strong evidence on the treatment. Vaccines are not yet available. Dexamethasone is effective in reducing mortality in severe forms. Conclusions: despite great efforts, as the number of confirmed cases increases, evidence on transmission, incidence, disease progression, lethality, effects and outcomes remain limited and without any high levels of evidence. Studies are still necessary for all aspects of the disease.

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Bibliographic Details
Main Authors: Souza,Alex Sandro Rolland, Amorim,Melania Maria Ramos, Melo,Adriana Suely de Oliveira, Delgado,Alexandre Magno, Florêncio,Anna Catharina Magliano Carneiro da Cunha, Oliveira,Thaise Villarim de, Lira,Lara Caline Santos, Sales,Lucas Martins dos Santos, Souza,Gabriela Albuquerque, Melo,Brena Carvalho Pinto de, Morais,Ítalo, Katz,Leila
Format: Digital revista
Language:English
Published: Instituto de Medicina Integral Prof. Fernando Figueira 2021
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1519-38292021000100029
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Summary:Abstract Objectives: to review the available literature on the general aspects of SARS-CoV-2 infec-tion. Methods: this is a narrative literature review carried out from March to September 2020. Results: COVID-19 caused by the new coronavirus or SARS-CoV-2, grows with devas-tating effects worldwide. The literature describes epidemiological data and mortality risk groups of the disease, which presents a high rate of transmission. Prevention is the most effective way to fight the disease, persisting the absence of strong evidence on the treatment. Vaccines are not yet available. Dexamethasone is effective in reducing mortality in severe forms. Conclusions: despite great efforts, as the number of confirmed cases increases, evidence on transmission, incidence, disease progression, lethality, effects and outcomes remain limited and without any high levels of evidence. Studies are still necessary for all aspects of the disease.

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