Mycobacterium tuberculosis belonging to family LAM and sublineage RD Rio: common strains in Southern Brazil for over 10 years
A sublineage of Mycobacterium tuberculosis called RD Rio was described in 2007. Although only recently described, this strain may have been present previously in the population, and its identification in clinical isolates will elucidate bacterial transmission dynamics and host-pathogen interactions. This study evaluated the clonal diversity of the RD Rio sublineage in clinical isolates from Rio Grande-RS obtained between 1998 and 2001. Among the 45 samples analyzed by the MIRU-VNTR method, there were six clusters with two samples each and 33 orphan strains with unique pattern. The strains were distributed across several different lineages including LAM (34.04%), X (14.89%), Haarlem (12.77%), UgandaI (10.64%), S (4.26%), NEW-1 (2.13%) and Cameroon (2.13%); 14.89% of the strains matched to multiple lineages. RD Rio strains were present in 28.9% of the samples and 81.25% of the identified strains belonged to the LAM family. The high clonal diversity observed in this study is a constant feature in this region. The RD Rio sublineage has been in Rio Grande-RS since 1998. The continued monitoring of RD Rio in clinical isolates will enhance the understanding of its epidemiological significance.
Main Authors: | Soares,Renata Oliveira, Macedo,Maíra Bidart de, von Groll,Andrea, Silva,Pedro Eduardo Almeida da |
---|---|
Format: | Digital revista |
Language: | English |
Published: |
Sociedade Brasileira de Microbiologia
2013
|
Online Access: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822013000400032 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Simultaneous Detection of Mycobacterium tuberculosis and Mycobacterium avium Complex by a Multiplex PCR
by: Souza,Mariana Quaresma de, et al.
Published: (2023) -
Genomic analysis of Latin American-Mediterranean family of Mycobacterium tuberculosis clinical strains from Kazakhstan
by: Tarlykov,Pavel, et al.
Published: (2020) -
Drug resistance of Mycobacterium tuberculosis strains in southern Brazil
by: Grutzmacher,Laynara Katize, et al.
Published: (2012) -
Assessing and screening for T-cell epitopes from Mycobacterium tuberculosis RD2 proteins for the diagnosis of active tuberculosis
by: Chen,Jiazhen, et al.
Published: (2018) -
Mycobacterium tuberculosis strains of the Beijing genotype are rarely observed in tuberculosis patients in South America
by: Ritacco,Viviana, et al.
Published: (2008)