Decellularized Wharton’s Jelly: Biomaterial Potential for Regenerative Medicine Applications - A Mini-Review

Decellularized Wharton’s Jelly: Biomaterial Potential for Regenerative Medicine Applications - A Mini-Review

Abstract The use of Wharton's Jelly (WJ) as a biomaterial is currently undergoing an appearance in the regenerative medicine field. The biomaterials applications focus on the aspects of cellular growth or delivery of proteins capable of stimulating cellular response. However, the basic knowledge about Wharton jelly and decellularization processing technology combined with understanding the physical-chemical properties of this biomaterial is necessary for proper application in regenerative medicine. This mini-review article summarizes information on the composition of WJ, application of drug delivery, in medicine and discusses recent developments with a special focus on its use for regenerative medicine. The most successful and stimulating applications are studies in regenerative medicine and tissue engineering, for wound healing to treat burns, tumor treatment, nanoparticle carriers, and drug delivery systems.

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Main Authors: Gamba,Luize Kremer, Ribeiro,Victoria Stadler Tasca, Simeoni,Rossana Baggio, Gamba,Laiza Kremer, Graf,Elis Cristine Bevian, Denk,Marcos Antônio, Almeida,Meila Bastos de, Simeoni,Paulo Ricardo Baggio, Barbosa,Carlos de Almeida, Francisco,Julio Cesar, Guarita-Souza,Luiz Cesar
Format: Digital revista
Language:English
Published: Instituto de Tecnologia do Paraná - Tecpar 2023
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132023000100303
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spelling oai:scielo:S1516-891320230001003032022-09-13Decellularized Wharton’s Jelly: Biomaterial Potential for Regenerative Medicine Applications - A Mini-ReviewGamba,Luize KremerRibeiro,Victoria Stadler TascaSimeoni,Rossana BaggioGamba,Laiza KremerGraf,Elis Cristine BevianDenk,Marcos AntônioAlmeida,Meila Bastos deSimeoni,Paulo Ricardo BaggioBarbosa,Carlos de AlmeidaFrancisco,Julio CesarGuarita-Souza,Luiz Cesar cell seeding decellularized Wharton's jelly matrix natural scaffolds tissue decellularization Wharton's jelly matrix. Abstract The use of Wharton's Jelly (WJ) as a biomaterial is currently undergoing an appearance in the regenerative medicine field. The biomaterials applications focus on the aspects of cellular growth or delivery of proteins capable of stimulating cellular response. However, the basic knowledge about Wharton jelly and decellularization processing technology combined with understanding the physical-chemical properties of this biomaterial is necessary for proper application in regenerative medicine. This mini-review article summarizes information on the composition of WJ, application of drug delivery, in medicine and discusses recent developments with a special focus on its use for regenerative medicine. The most successful and stimulating applications are studies in regenerative medicine and tissue engineering, for wound healing to treat burns, tumor treatment, nanoparticle carriers, and drug delivery systems.info:eu-repo/semantics/openAccessInstituto de Tecnologia do Paraná - TecparBrazilian Archives of Biology and Technology v.66 20232023-01-01info:eu-repo/semantics/articletext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132023000100303en10.1590/1678-4324-2023220292
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libraryname SciELO
language English
format Digital
author Gamba,Luize Kremer
Ribeiro,Victoria Stadler Tasca
Simeoni,Rossana Baggio
Gamba,Laiza Kremer
Graf,Elis Cristine Bevian
Denk,Marcos Antônio
Almeida,Meila Bastos de
Simeoni,Paulo Ricardo Baggio
Barbosa,Carlos de Almeida
Francisco,Julio Cesar
Guarita-Souza,Luiz Cesar
spellingShingle Gamba,Luize Kremer
Ribeiro,Victoria Stadler Tasca
Simeoni,Rossana Baggio
Gamba,Laiza Kremer
Graf,Elis Cristine Bevian
Denk,Marcos Antônio
Almeida,Meila Bastos de
Simeoni,Paulo Ricardo Baggio
Barbosa,Carlos de Almeida
Francisco,Julio Cesar
Guarita-Souza,Luiz Cesar
Decellularized Wharton’s Jelly: Biomaterial Potential for Regenerative Medicine Applications - A Mini-Review
author_facet Gamba,Luize Kremer
Ribeiro,Victoria Stadler Tasca
Simeoni,Rossana Baggio
Gamba,Laiza Kremer
Graf,Elis Cristine Bevian
Denk,Marcos Antônio
Almeida,Meila Bastos de
Simeoni,Paulo Ricardo Baggio
Barbosa,Carlos de Almeida
Francisco,Julio Cesar
Guarita-Souza,Luiz Cesar
author_sort Gamba,Luize Kremer
title Decellularized Wharton’s Jelly: Biomaterial Potential for Regenerative Medicine Applications - A Mini-Review
title_short Decellularized Wharton’s Jelly: Biomaterial Potential for Regenerative Medicine Applications - A Mini-Review
title_full Decellularized Wharton’s Jelly: Biomaterial Potential for Regenerative Medicine Applications - A Mini-Review
title_fullStr Decellularized Wharton’s Jelly: Biomaterial Potential for Regenerative Medicine Applications - A Mini-Review
title_full_unstemmed Decellularized Wharton’s Jelly: Biomaterial Potential for Regenerative Medicine Applications - A Mini-Review
title_sort decellularized wharton’s jelly: biomaterial potential for regenerative medicine applications - a mini-review
description Abstract The use of Wharton's Jelly (WJ) as a biomaterial is currently undergoing an appearance in the regenerative medicine field. The biomaterials applications focus on the aspects of cellular growth or delivery of proteins capable of stimulating cellular response. However, the basic knowledge about Wharton jelly and decellularization processing technology combined with understanding the physical-chemical properties of this biomaterial is necessary for proper application in regenerative medicine. This mini-review article summarizes information on the composition of WJ, application of drug delivery, in medicine and discusses recent developments with a special focus on its use for regenerative medicine. The most successful and stimulating applications are studies in regenerative medicine and tissue engineering, for wound healing to treat burns, tumor treatment, nanoparticle carriers, and drug delivery systems.
publisher Instituto de Tecnologia do Paraná - Tecpar
publishDate 2023
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132023000100303
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